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[ Up ] [ Hypoglycemia ] [ Diabetic Foot ] [ Diabetic Eye complications ] [ Diabetes and Kidney damage ] [ Diabetic Neuropathy ] [ Macrovascular complications ] [ Lipid disorder in diabetics ] [ Hypertension in diabetics ] [ Diabetic Ketoacidosis ]
Macro vascular
disease in diabetics.
Atherosclerotic changes in blood vessel Diabetes
melitus is a major risk factor for disability and increased death rate through
premature and accelerated Atherosclerosis. (deposits in blood vessels leading to
their narrowing).
  
heart
attacks
stroke high blood pressure
(narrowing of
arteries of
heart) (narrowing of brain
arteries) (generalized narrowing of
arteries)
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Coronary
artery disease leading to angina and heart attacks is 2-4 times as common in
a diabetic. (sudden heart attack can occur without much pain)
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Cerebrovascular
disease leading to stroke is 2-4 times as common in a diabetic.
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Peripheral
vascular disease is common, causing foot problems.
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Hypertension
also more common in diabetics.
Damage to large blood vessels
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Perhaps the greatest problem caused by damaged large blood vessels is heart
disease. | |
When the blood vessels of the heart become blocked or damaged, the
heart does not get enough blood. | |
You may be at an even greater risk for heart
disease if you smoke or have high blood pressure or high cholesterol levels. |
If
the damage centers around the blood vessels in the arms, legs, or feet, this is
called peripheral vascular disease.
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The warning signs for heart disease and peripheral vascular disease include
chest pain, shortness of breath, swollen ankles, and an irregular heartbeat. | |
With peripheral vascular disease, you may also have weakness, pain, and cramping
when you walk; you will not experience these feelings when standing or sitting.
Other symptoms include cold feet, loss of hair on your feet or legs, and a
reddening of dangling feet. Report any symptoms to your doctor. |
Damage to small blood vessels
Diabetes can affect the small blood vessels in the eyes and kidneys.
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Blood
from a leaking vessel can cause blurred vision, dark spots, loss of some vision,
and even lead to blindness. Sometimes you may not know that small blood vessels
in the eye have been damaged. Have your eyes checked regularly. | |
Kidney disease is another serious complication of small blood vessel damage.
The tiny vessels of the kidney filter waste products out of the blood and
excrete them in the urine. When the vessels are damaged, the filters cannot take
all of the waste out of the blood. Regular visits to your doctor are crucial,
especially at the first sign of trouble. |
Mechanism
of damage to blood vessels in a diabetic patient.
When
blood-glucose levels remain high for too long, the excess glucose stiffens red
blood cells and weakens blood vessel walls. When the stiffened red blood cells
try to squeeze into the extremely small blood vessels, they damage the vessels
even more. This can cause small blood vessels to become weaker and burst. As the
stiffened red blood cells pass through the large vessels, they damage the inside
walls and scar tissue forms. Cholesterol in the blood becomes trapped by the
rough scar tissue and begins to build up. It can gradually close off the large
blood vessels and force your heart to pump harder.
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