Cognitive Deficits Via Poison Dioxin;
Chemical Mixtures Intensify Damage;
Low Graduation Rates, Jacksonville FL.

This page: http://www.geocities.com/fltaxpayer/endocrine/11studies.html

General Note: Dioxin causes expensive disabilities like ADD/ADHD. Eliminate endocrine disruptors like dioxin and save $4,000/year/household on unnecessarily high Medicare and private medical insurance, disability taxes and extra income taxes to make up for taxes not paid by unnecessarily disabled people.

Ref.11
Two Studies showing chemical mixtures intensify
damage

Child Development and Common Chemical Mixtures:
ADD, ADHD, Violence, Aggression?


===========================
Study Sees Dangers in The Water Research on Mice
Hints Chemicals Could Harm Kids

Wisconsin State Journal
(Copyright Madison Newspapers, Inc.
1999) Publication Date: March 16, 1999
NewsReal's IndustryWatch


[Part of this subject was previously reported by "Our
Toxic Times" monthly published by the Chemical
Injury Information Network: http://www.ciin.org
(Address revised 10/29/2001)


A mix of chemicals commonly found in ground water
altered the development of young mice and indicates a
threat may exist for children, a UW-Madison professor
said Monday in releasing a five-year study.

When it comes to toxic chemicals, there's more to
worry about than cancer, said Warren Porter, professor
of zoology and toxicology.

Porter's study, published Monday in the journal
Toxicology and Industrial Health, supports an
emerging theory that mixtures of pesticides, herbicides
and fertilizers may affect the intelligence, motor skills
and personalities of infants, toddlers and preschoolers.

It suggests that combinations of commonly used
agricultural chemicals - in concentrations found in
Wisconsin ground water - can influence thyroid
hormones, which may affect how the brain of a fetus
or young child develops.

Porter's research used mice that were given drinking
water laced with a common mix of pesticides and
fertilizers.

The drinking water altered the thyroid hormones in
young mice, changed their aggression levels, and
suppressed their immune systems.

Porter said his research, based on water quality data
from the state Department of Natural Resources,
supports other studies that looked at children exposed
to pesticides.

"It's not much of a leap to go from a mouse to a human
when you are talking about the level of a chemical that
might induce cancer or mutations," he said.

Children have developing brains and immune systems
and are "especially vulnerable" to changes in thyroid
hormones.

To complement his study, Porter cited tests in the state
of Sonora, Mexico, where scientists found striking
differences in hand- eye coordination and other mental
and physical skills when comparing Yaqui Indian
preschoolers in an agrarian region with those in
adjacent foothills where no pesticides were used.

Four-and 5-year-olds living in the farm valley had
trouble performing a variety of simple motor skills
such as drawing stick figures, catching a 12-inch ball
from about four yards away, and dropping raisins into
a bottle cap from a distance of six inches.



The children exposed to pesticides also had poorer
memory skills and were more prone to physical
aggression and angry outbursts.

The Mexican case could be called extreme, but Porter
said it may be more universal than some would
believe.

"Data suggest that we may be raising a generation of
children with higher proportions of learning disabilities
and hyper-aggression," he said.

Porter's study focused on three commonly used farm
chemicals: atrazine, an herbicide; aldicarb, an
insecticide; and nitrate, a chemical fertilizer.

The mice exhibited altered immune, endocrine and
nervous system functions.

Those changes, according to Porter, occurred at
concentrations currently found in Wisconsin ground
water.

Effects were most noticeable when a single pesticide
was combined with nitrate fertilizer.

This was true for herbicides, as well as insecticides,
and chips away at the notion that herbicides have no
significant effect on animals.

"Herbicides are not the harmless chemicals they are
sometimes portrayed to be," Porter said.

"Herbicides can be every bit as biologically active as
insecticides or fungicides."

Although activated charcoal filters can reduce
pesticide levels, they are not typically used by
municipal water plants.

Bottled water also may contain unsafe pesticide levels.

In Madison, however, water utility officials said their
own testing has revealed no problems.

"We do pesticide testing every three years," said
Marilyn Dukes- Winters, water resources supervisor
for the Madison Water Utility.

"There are 25 to 35 chemicals that we test for.

And we've not found any quantifiable levels in any
Madison wells."

Porter said it is important not to focus on his study
alone.

Another study, he said, has showed that birth defects in
children of Minnesota pesticide applicators were
higher than in the general population.

"The apparent influence of pesticide and fertilizer
mixtures on the endocrine system (the system of
glands such as the thyroid that secrete hormones into
the bloodstream) may have a cascade effect, spilling
over to the immune system and affecting fetal brain
development," Porter said.

Some [with a vested interest] are skeptical.

Pesticide company representatives and some
toxicologists are skeptical that commonly found levels
of pesticides can alter human thyroid hormones.

"I'm kind of dubious that low-level exposures to
chemicals are raising all kinds of havoc with the
endocrine system," said John McCarthy, vice president
of the American Crop Protection Association in
Colorado.

There are so many studies coming out every week, it is
important to see what they show collectively, said
Amy Winters, vice president of government relations
for the Wisconsin Agribusiness Council.

"We are concerned about the implications of this
study," she said.

"But we need to take a closer look at how it compares
with other studies on endocrine response to pesticides
and fertilizers."

Porter is on sabbatical from UW-Madison and now
working as a researcher at the National Center for
Ecological Analysis in Santa Barbara.

Co-authors of Porter's study include James Jaeger of
the UW- Madison zoology department and Ian Carlson
of the University Hospital Endocrinology Laboratory.

Porter said he believes this type of research is in its
early stages and that more work needs to be done in
assessing risks based on combinations of pesticides
and fertilizers.



"But the single most important finding of the study is
that common mixtures, not the standard
one-chemical-at-a-time experiments, can show
biological effects at current conditions in ground
water," Porter said.

"I think we have added something to a growing body of
evidence."
===========================


ED Briefing Book Main Pages:
| Endocrine Disruption Briefing Book | | Attachment List, ED Briefing Book |

Attachment Pages:
| ADD/ADHD | | Children-Developmental Damage | | Symptoms, Physical-Cognitive | | Diabetes | | Porphyria-LiverSpots | | Porphyria-Suppressed Detox | | Thyroid Disruptions | | Cancer, et al | | Cancer, et al |

| Bethune School Dioxin | | Whitehouse School Scandal | | Belgium Govt. Topples | | 314 Toxic Chemicals | | 3700 Porphyrinogenic Chemicals | | Professional Dioxin Reports | | Industry View Dioxin | | Dust Carries Toxics (Dioxin) |

Cost Estimates, For Medical & Social Problems: |
Overview 5 most costly dioxin diseases |

Additional Overview Info:
| PCB Toxicity by CDC | | 48% Graduation Rate Jax FL | | EDSTAC |
| EPA Dioxin Report Chap 9, Health Effects | | EPA 1994 Dioxin Report, other chapters | | Court Affidavit of Dioxin Damage | | Solutions to Dioxin Problem |


Send questions to:
| [email protected] | | [email protected] |

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