Mechanism of action: it is a potent potassium-channel blocker; it binds to the K-receptors on the beta cells in the pancreas and closes the ATP-dependent potassium channels.

Major side effects: perspiration, headache, palpitations, numbness of the mouth, tingling in the fingers, tremors, muscle weakness, blurred vision, hypothermia, uncontrolled yawning, irritability, mental confusion, sinus tachycardia, shallow breathing, and loss of consciousness.

MEGLITINIDES	Brand Names	Drug Interaction	Contraindication	Dosage	Costs per Month
Repaglinide	Prandin	Barbituates Thiazide diuretics Phenothiaziness Salicylate Sulfonamide Thyroid hormones	Heart disease Hypersensitivity Pregnancy	4mg qd 1-2mg tid	1mg qd: $60.00 - 69.99