| * denotes home games. | |||||||||||
| 1960 (4-5) | Drake Freshmen Allowed to Play Varsity | 1961 (5-4) | |||||||||
| Coach: Bus Mertes | Coach: Bus Mertes | ||||||||||
| Iowa State | L | 0-46 | Iowa State* | L | 0-21 | ||||||
| Southeast Missouri State* | W | 17-6 | Southern Illinois | W | 7-0 | ||||||
| Northern Iowa | L | 3-14 | Colorado State | W | 7-0 | ||||||
| Colorado State | L | 0-30 | Northern Iowa* | W | 21-6 | ||||||
| Evansville* | W | 14-0 | Idaho State* | L | 11-12 | ||||||
| North Texas | L | 7-29 | Bradley* | W | 24-13 | ||||||
| Bradley* | W | 14-6 | North Texas | L | 21-28 | ||||||
| Washington (Mo.)* | W | 21-6 | Wichita State | L | 13-20 | ||||||
| Wichita State* | L | 7-32 | Nebraska-Omaha | W | 36-13 | ||||||
| 1962 (8-2) | 1963 (4-4) | ||||||||||
| Coach: Bus Mertes | Coach: Bus Mertes | ||||||||||
| Iowa State | L | 7-14 | Cincinnati | L | 0-28 | ||||||
| Southern Illinois* | W | 14-13 | Missouri State | L | 6-13 | ||||||
| Colorado State* | W | 21-0 | South Dakota* | W | 23-0 | ||||||
| South Dakota | W | 15-14 | Northern Iowa* | W | 21-12 | ||||||
| Northern Iowa | W | 21-15 | Bradley | W | 27-8 | ||||||
| Wichita State* | W | 10-0 | Idaho State* | W | 15-12 | ||||||
| Bradley | W | 30-13 | Western Illinois | L | 12-14 | ||||||
| Idaho State | L | 14-33 | Nebraska-Omaha* | L | 29-34 | ||||||
| North Dakota State* | W | 40-6 | N23 | Iowa State | [cancelled] | ||||||
| Evansville | W | 32-0 | |||||||||
| 1964 (6-4) | 1965 (6-4) | ||||||||||
| Coach: Bus Mertes | Coach: Jack Wallace | ||||||||||
| Iowa State | L | 0-25 | Iowa State* | L | 0-21 | ||||||
| South Dakota | W | 28-14 | South Dakota | W | 17-0 | ||||||
| Western Illinois* | L | 12-14 | Missouri State* | W | 24-8 | ||||||
| Northern Iowa | L | 14-41 | Northern Iowa* | W | 31-7 | ||||||
| Southern Illinois* | L | 19-28 | Southern Illinois | W | 28-12 | ||||||
| Nebraska-Omaha | W | 24-19 | Western Kentucky | L | 21-28 | ||||||
| Bradley* | W | 46-19 | Abilene Christian | W | 24-7 | ||||||
| South Dakota State* | W | 37-15 | West Texas A&M | L | 14-20 | ||||||
| Abilene Christian* | W | 14-3 | Louisville* | L | 17-32 | ||||||
| Louisville | W | 14-8 | Nebraska-Omaha* | W | 36-30 | ||||||
| 1966 (8-2) | 1967 (4-5) | ||||||||||
| Coach: Jack Wallace | Coach: Jack Wallace | ||||||||||
| Northwest Missouri State* | W | 27-0 | Louisville* | L | 0-46 | ||||||
| Northern Iowa | W | 9-6 | North Texas | L | 0-31 | ||||||
| Southern Illinois* | W | 30-7 | Wichita State | L | 13-46 | ||||||
| Wichita State* | W | 34-16 | Northwest Missouri State | W | 7-0 | ||||||
| Louisville | L | 26-66 | Northern Iowa* | W | 10-7 | ||||||
| Western Kentucky* | W | 37-21 | Nebraska-Omaha* | W | 23-15 | ||||||
| North Texas* | W | 17-13 | South Dakota State | W | 34-21 | ||||||
| Quantico Marines | L | 13-21 | South Dakota* | L | 35-37 | ||||||
| South Dakota* | W | 31-14 | Southern Illinois | L | 17-45 | ||||||
| Nebraska-Omaha | W | 53-0 | |||||||||
| 1968 (5-5) | 1969 (7-2-2) | ||||||||||
| Coach: Jack Wallace | Coach: Jack Wallace | ||||||||||
| Northern Arizona* | W | 30-14 | Louisville* | T | 24-24 | ||||||
| Arkansas State* | L | 14-46 | South Dakota State | W | 21-16 | ||||||
| Quantico Marines* | L | 31-33 | North Texas* | W | 27-23 | ||||||
| Wichita State | W | 26-23 | Northern Iowa* | L | 13-23 | ||||||
| Northern Iowa | L | 19-21 | Nebraska-Omaha | W | 31-21 | ||||||
| Nebraska-Omaha | W | 32-14 | Western Illinois* | W | 44-7 | ||||||
| Southern Illinois* | L | 20-21 | South Dakota | W | 29-24 | ||||||
| South Dakota | L | 28-49 | Arkansas State | T | 21-21 | ||||||
| South Dakota State* | W | 28-20 | Southern Illinois | W | 19-17 | ||||||
| Louisville | W | 38-37 | Idaho State | W | 58-30 | ||||||
| D13 | Arkansas State# | L | 21-29 | ||||||||
| #Pecan Bowl at Arlington, Texas | [note] | ||||||||||
| **Karl Kassulke in Super Bowl IV, January 1970** | |||||||||||
