There's only one road from Metro Manila going to Real, Quezon, so whether you're in a car or in an FX Taxi, the road is the same. Take Ortigas Avenue Extension until at joins with the Manila East Road. Go down this road all the way to Quezon. There's a fork in the road in Laguna. The one that goes right ends in Siniloan. Straight ahead to Pagsanjan/Sta.Cruz to Famy and to Real.
