Ÿ°¹±Ì ×™�� �º³ »Ì‘«×‘É �ÉÅ �º‘³ �¥‘�Å �ŞÚ¿ —º‘Ϫ�è ‚�Å. µÅ �Ì®™�� �æ��‘ÓϹ³ �â�¯¥ ×‘ì œ™±€Æ¿ —º�:-

�™�� ŠÏ ¶€ÒÆ‘î ¶€ÒÇÖ ƒÏ™� �ׯ¨À‘î‘Ö,� ÀûH �™�æ¥� �œÑ¹³,ŠÏ ºÌÀ‘®(molecule) צØÓÏ™�Å. �‘Ì«Å:-
-O- �� »Ì‘«×‘É �, ƒÌ¯¨ H+ �™�æ¥� �œÑ¹³,H-O-H (H2O) �� ºÌÀ‘®(molecule) ‚�ÚÅ, -O- �� »Ì‘«×‘É �, Àú³é‘Ï -O- �Ú¥� �œÑ¹³,O=O (O2) �� ºÌÀ‘®(molecule) ‚�ÚÅ ¶€ÒÆ‘� ƒÏ™�Å.
»Ì‘«×‘É �ÉÅ �º‘³,€�€Æ� �‘�«‘Å �‘€Ò� �‘�«‘Å �� ŠÏ ¶€ÒÇÖ �° ºÌÀ‘®(molecule) ±�àÅ.ŠÏ ¿�Ì‘ª�¥‘€�(proton) �¹³, '—µ�§Ü œ‘Ñ�' —�‘¯¥ ŠÏ ¶€ÒÆûH °À€Æ¿ —º�.�‘Ì«Å:- H-O-H (H2O) �� ºÌÀ‘®(molecule) ŠÏ H+ �¹³ OH-(hydroxyl) �� ¶€ÒÇÕÅ, O=O (O2) �� ºÌÀ‘®(molecule) ŠÏ O= �¹³ O= (superoxide)�� ¶€ÒÇÕÅ, ƒÏ™�Å. ƒ°€ûĞ °‘ò µ‘Å Ÿ°¹±Ì ×™�� �� ˜ì�é‘Å.ƒ³ �º‘Ö ÀûH Ÿ°¹±Ì ×™�� 1O2(singlet oxygen),H2O2(hydrogen peroxide).

ŠÏ Ÿ°¹±Ì × �Ì®€×´ °‘™�Å
ŠÏ �íº€ûÛ º¥Å.ŠÜ—×‘Ï �Ì®™�€ãÉÅ
ŸÀ‘Ñ 10,000 °¥€× ƒ¿º¦ Ÿ°¹±Ì ×™��
�À‘³×°‘�¢ —œ‘Ö�é‘Ñ�è!

Ÿ°¹±Ì ×™�æ™� ‹Ñ Ší�À �û³×‘Ö �€€ûбÕÅ »Ì‘«×‘É(oxygen) � ƒÏ™�Å,'—µ�§Ü œ‘Ñ�' —�‘¯¥ ŠÏ ¶€ÒÆûH °ÀÇÖ ƒÏ™�Å.�° ¶€ÒÇÖ ˆ°‘׳ Šò�� ƒ€«Æ´ ³¦Æ‘´ ³¦™�Å.�¿º¦ ƒ€«ÉÅ �º‘³ �€� ‚™�Ì«Å(oxidation) �� —œ‘ÖבÑ�è.�° ƒ€«¿€º´ °¨™�Å ×™� antioxidant �Ò³ free radical scavangers (Ÿ°¹±Ì × Øà›�) �� —œ‘ÖבÑ�è!

Ÿ°¹±Ì ×™�� ×Ó€À€Æ µ‘Å —°Í¹³ —�‘è� �ׯ¨À‘î‘Ö,H2O2(hydrogen peroxide) �� ±Ì×´€° ב›�, 2 —œ‘ª€¥ ŠÏ ³¬ÇÖ —º‘ª¥‘Ö —°ÍÉÅ---�¿º¦�Æ ³¬ —×æ´³¿ �º‘ËبÅ.³¬�� �° �±—Æ‘Ö µÅ �Ì®™�� �À‘´±ÌÅ?

Ÿ°¹±Ì ×�è(free radicals) µÅ �Å»Ö —œËÉÅ ²€À�è:-

µÀ³ � (gene) œÅº¹°¿ºª¥ DNA � �Ñ � �ÏØÖ(nucleous) �œ°¿º¨´³°Ö.

�Ñ �™�€� Ÿí�èã œÜØÖ —�‘࿽ peroxidation � ��¿º¨´³°Ö.

.�Ñ �™�äÖÕèã'�€'�€� ( enzymes) µ‘œ¿º¨´³°Ö.

Antioxidant ت¥Áã‘� ت¥Á� C, '¼ª¥� —�̪§�'(ت¥Á� A) �ã€× �Å»Ö �€é´°Ö.

Low density lipoprotein —�‘à