Research indicates that in people over the age of 30, almost everyone with Down's syndrome shows the neuropathological signs of Alzheimer's disease, although the clinical signs may not be visible and can be hard to detect in the early stages

Intially the symptoms are relatively mild with short term memory loss, difficulty with language and behavioral changes. These become more pronounced as speech becomes difficult, disorientation and states of confusion increase. It may also become harder to control bodily functions

Diagnosis follows a similar course to that for Alzheimer's and includes blood tests, neuroimaging and MMSE tests

Treatment and support are similar to the requirements of Alzheimer's disease and emphasis should be placed on supporting the individual cope with their changing perception of the world. Drugs may also be prescribed and community support made available. This needs to be incorporated into the support for treatment of Down's Syndrome itself

General information is contained within the Alzheimer's sections, but more specific details can be found below:

http://www.zarcrom.com/users/alzheimers/odem/ds-d.html

http://www.learningdisabilities.org.uk/page.cfm?pagecode=AUPUUPBRDE