Medicinal Use of Cannabis


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Science and Technology Select Committee's report 'Cannabis, the scientific and medical evidence':
"8.2     ....we have received enough anecdotal evidence (see above, paragraphs 5.4, 20-22, 27-30) to convince us that cannabis almost certainly does have genuine medical applications, especially in treating the painful muscular spasms and other symptoms of MS and in the control of other forms of pain.
8.3     We therefore recommend that clinical trials of cannabis for the treatment of MS and chronic pain should be mounted as a matter of urgency. "
8.9     Unlike cannabis itself, the cannabinoid THC (dronabinol) and its analogue nabilone are already accepted by the Government as having medical value (paragraphs 5.11-17)—producing the anomaly that, while cannabis itself is banned as a psychoactive drug, THC, the principal substance which makes it psychoactive, is in legitimate medical use. Some of our witnesses are prepared (paragraph 5.50) to contemplate wider medical use of the cannabinoids, but not of cannabis itself. We disagree, since some users of both find cannabis itself more effective (paragraph 5.51).
8.10     Dronabinol (THC), though not licensed in this country, has already been moved to Schedule 2 to the Misuse of Drugs Regulations, and nabilone is a licensed medicine and not a controlled drug; so no Government action is required in either case to permit clinical trials or indeed prescription. All cannabinoids other than THC remain in Schedule 1, and transferring them would require agreement through the WHO under the 1971 Convention. We do not regard this as a priority, since we are not persuaded that any other cannabinoid has a convincing medical use; but we recommend that the Government should raise the matter of rescheduling the remaining cannabinoids with the WHO in due course, in order to facilitate research.
www.parliament.the-stationery-office.co.uk/pa/ld199798/ldselect/ldsctech/151/15101.htm

Independent Drug Monitoring Unit:
"There is also a substantial body of research, much of it historical and/or anecdotal, but supported by a number of laboratory studies on animal models, to demonstrate increased tolerance of pain from administration of cannabis or individual, cannabinoids, including THC. Other studies have shown a temporary decrease in intraocular pressure in Glaucoma patients, a reduction in brain-cell death following strokes, relief from muscle spasms in MS, reduced seizure frequency and intensity in epilepsy, stimulation of appetite in AIDS and anorexia, bronchodilation in asthma, relief from the symptoms of irritable bowel syndrome, alcohol or opiate withdrawal, and a variety of other medical uses.
Although the scientific evidence is equivocal, more users report ‘relaxation’ as an effect of cannabis use than any other ‘benefit’.
The BMA recommended that THC and/or other cannabinoids be made available for prescription and research for patients with intractable pain. The House of Lords Science & Technology Select Committee recommended that doctors should be allowed to prescribe cannabis for medical use, and that a prescription should form a defence against prosecution for cannabis offences."
www.idmu.co.uk/summed.htm

Illnesses helped by cannabis:

"AIDS Wasting Syndrome; Arthritis; Brain Injury/Stroke; Multiple Sclerosis; Nausea associated with cancer chemotherapy; Pain; Phantom Limb Pain; Spinal cord injury; Anti-Tumor Effects; Asthma; Crohn's Disease and Ulcerative Colitis; Depression and Mental Illness; Eating Disorders; Epilepsy; Fibromyalgia; Glaucoma; High Blood Pressure/Hypertension; Migraine; Nail Patella Syndrome; Schizophrenia; Tourette's Syndrome"
www.gwpharm.com/cann_ther_index.html

Also: "Multiple Sclerosis, IBS, Addiction withdrawal, Huntington’s Chorea"
www.idmu.co.uk/medicinal.htm

Clinical trials:

"GW is part of the UK Medicinal Cannabis Project which has just launched a website where patients wishing to register their interest in taking part in one of GW's clinical trials can complete a patient questionnaire online (the questionnaire is located in the "Patients" section of their website.)."
www.idmu.co.uk/clinical.htm

"If you would like to be considered for a clinical trial you need to complete a confidential Patient Questionnaire which can be obtained by contacting GW, giving your name and address and stating that you would like to receive a Patient Questionnaire. You do not need to give any further information as the questionnaire will give you an opportunity to give all information that you think is relevant.
GW Pharmaceuticals plc
Porton Down Science Park
Salisbury
Wilts
SP4 0JQ
United Kingdom
Patient Information Line (UK Callers): 0800 052 7100 "
www.gwpharm.com/rese_clin_info.html

Evidence of cancerous tumour reduction in mice:

August 1974, The Washington Post:
"Under the headline, "Cancer Curb Is Studied," it read in part:
"The active chemical agent in marijuana curbs the growth of three kinds of cancer in mice and may also suppress the immunity reaction that causes rejection of organ transplants, a Medical College of Virginia team has discovered." The researchers "found that THC slowed the growth of lung cancers, breast cancers, and a virus-induced leukemia in laboratory mice, and prolonged their lives by as much as 36 percent."

February 2000:
"The Madrid researchers reported in the March issue of Nature Medicine that they injected the brains of 45 rats with cancer cells… Cannabinoid (THC)-treated rats survived significantly longer than control rats. Nine of the THC-treated rats surpassed the time of death of untreated rats, and survived up to 19-35 days. Moreover, the tumor was completely eradicated in three of the treated rats."
www.mapinc.org/drugnews/v01.n572.a11.html

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