-
Nathan Fillion as
Captain Malcolm "Mal" Reynolds
-
Gina Torres as
Zoë Alleyne-Washburne
-
Alan Tudyk as
Hoban "Wash" Washburne
-
Morena Baccarin as
Inara Serra
-
Adam Baldwin as
Jayne Cobb
-
Jewel Staite as
Kaywinnit Lee "Kaylee" Frye
-
Sean Maher as
Dr. Simon Tam
-
Summer Glau as
River Tam
-
Ron Glass as
Shepherd Derrial Book
-
Chiwetel Ejiofor as The Operative
-
David Krumholtz
as Mr. Universe
-
Michael Hitchcock
as Dr. Mathias
-
Sarah Paulson as
Dr. Caron
-
Yan Feldman as
Mingo
-
Rafael Feldman
as Fanty
-
Nectar Rose as
Lenore
-
Tamara Taylor as
Teacher
-
Glenn Howerton
as Lilac Young Tough
-
Hunter Ansley Wryn
as Young River
-
Logan Craig O'Brien
as Boy Student
-
Erik Erotas as
Boy Student
-
Demetra Raven as
Girl Student
-
Jessica Huang as
Girl Student
-
Marley McClean
as Girl Student
-
Scott Kinworthy
as Ensign
-
Erik Weiner as
Helmsman
-
Conor O'Brien as
Lab Technician
-
Peter James Smith
as Lab Technician
-
Weston I. Nathanson
as Trade Agent
-
CeCe Cline as
Young Female Intern
-
Chuck O'Neil as
Vault Guard
-
Amy Wieczorek as
Lilac Mom
-
Tristan Jarred
as Lilac Son
-
Elaine Lee as
Fan Dancer
-
Terrence Hardy
as Mining Camp Boy
-
Brian O'Hare as
Alliance Pilot
-
Ryan Tasz as
Black Room Soldier
-
Colin Patrick Lynch
as Black Room Soldier
-
Terrell Tilford
as News Anchor
- Joshua Kwiat
as Slovenly Beaumonde Man
