What would you do if you could relive a day? If you're Tru Davies, you'd save lives. Tru is a recent college graduate who - when her high-powered medical internship falls through - finds herself working the midnight shift at the city morgue. One night, Tru questions reality when she thinks she hears a murder victim asking for her help. But the next morning, our heroine wakes up to find that she is back at the beginning of that very same day - twelve hours before a death that only she knows about is set to take place.

Now with the clock ticking, Tru is compelled to traverse the city over the next twelve hours to try to prevent this tragedy, while at the same time trying to rescue members of her own family from their dangerous and self-destructive lives.

Tru Calling puts a stylish new spin on the procedural crime format as Tru uses her newfound ability to try to stop tragedies before they actually happen.

In the series, Tru is surrounded by Harrison, her handsome and charming younger brother who has a knack for finding trouble; Meredith, their older sister who has a great career and money, but battles drug addiction; Lindsay, Tru's loyal but unsuspecting best friend; and Davis, the quirky morgue staffer Tru works with on the graveyard shift.