General - risks, definition of NHRT | Which OHT? | Deciding on it | Getting off it | "Natural" hormones | Long term considerations |
pharmacology | photomicrographs | Provera et al (MPA | Prempro | tradenames | "natural"(NHRT) |
While the actual drugs tend
to be the same throughout the world, the names given to them vary somewhat
from country to country. Once you have found out the generic name for the
drug you are interested in, you can probably find out all (or more...)
than you want to know about it by searching for it on http://rxlist.com
A comprehensive table of available preparations may be found at http://earlymenopause.com/ukhrt.htm You can consult the British National Formulary at http://bnf.vhn.net/home/ After registering (free) you will find info about oestrogens in section 6.4.1.1 and about progestogens at 6.4.1.2 |
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Extract from http://www.exnet.com/staff/sys4/hrt.html
Conjugated Oestrogens (Premarin and Prempak) Conjugated oestrogens have
been the most widely used type of natural oestrogen and most of the safety
information we have about HRT is obtained from the use of these tablets.
Conjugated oestrogens are extracted from the urine of pregnant mares and,
although there has been some concern about the well being of these animals,
there is also reassurance from the pharmaceutical company that the farming
conditions are satisfactory. It is treatment with these tablets that gives
us most of the information on the prevention of oseoporosis and heart disease.
Other Natural Oestrogens (eg. Cyclo-progynova, Climagest, Nuvelle, Trisequens, Tridestra, Kliofem) Most other tablet forms of
HRT contain oestrodiol valerate or a similar compound and these tablets
are extracted from soya beans. While these preparations appear to be the
same strength as conjugated oestrogen tablets, we do not yet have the many
years of scientific research to be certain of the risks and benefits of
this treatment although they are likely to be as effective as conjugated
oestrogens. Two new preparations in this group have recently been introduced
to reduce the number of menstrual periods in women on hormone replacement
therapy. Tridestra provides a period every three months and Kliofem provides
continuous oestrogen and progesterone tablets, resulting in no periods
in some women.
Synthetic oestrogens All oral contraceptive pills contain ethinyloestradiol, a strong synthetic oestrogen designed to prevent ovulation. Oral contraceptive pills have often been used as HRT in young women. The oral contraceptive pills however, because they are stronger than natural oestrogens, do carry a small increased risk of blood clotting (thrombosis) which does not occur with oestradiol valerate or conjugated oestrogens. For many women with oestrogen deficiency, the oral contraceptives may be unnecessarily strong for use as HRT. |
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Non-equine alternatives
for oestrogen replacement
|
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More preparations (with comments) can be found at http://www.dotpharmacy.co.uk/uphrt.html |
General - risks, definition of NHRT | Which OHT? | Deciding on it | Getting off it | "Natural" hormones | Long term considerations |
pharmacology | photomicrographs | Provera et al (MPA | Prempro | tradenames | "natural"(NHRT) |