Pharmacology of Antimicrobials and Cytotoxic drugs

 

 

51.  The following tetracycline(s) is/are safe to use in renal failure:

 

a.    T: excreted mainly in the bile and faeces.

b.    F

c.    F

d.    F

 

 

52.    The following bacteria is/are sensitive to gentamicin:

 

a.      F: streptococcus and anaerobes are resistant to gentamicin.

b.      T: gentamicin is the drug of choice for enterobactericeae infections.

c.      T

d.      F

 

 

53.    Gentamicin:

 

a.      F

b.      T

c.      F

d.      F

 

 

54.     Penicillins:

 

a.      T

b.      T

c.      T

d.      T

 

 

55.    Vidarabine:

 

a.     T

b.     T

c.     F

d.     F

 

 

56.    Nystatin:

 

a.      F: binds to ergosterol in cell membrane and increases permeability leading to cell lysis.

b.      F: poor oral absorption.

c.      F: too toxic for parenteral uses; used topically for vaginal and oropharyngeal candidiasis.

d.      T

 

 

57.    Vancomycin may produce the following adverse effect(s):

 

a.      T

b.      T

c.      T

d.      T

 

 

58.    The following inhibits bacterial cell wall synthesis:

 

a.      F

b.      T

c.      T

d.      T

 

 

59.    The danger of crystalluria with sulfonamides is reduced by:

 

a.      F

b.     T

c.     F

d.     T

 

 

60.

 

a.     F

b.     F

c.     T

d.     F

 

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