Pharmacology of Antimicrobials and Cytotoxic drugs

 

 

31.    The cephalosporins:

 

a.      T: Cefamandole and cefoxitin are second generation cephalosporins.

b.      T

c.      T

d.      F

 

 

32.    The adverse effects of tetracyclines:

 

a.      T

b.      T

c.      T

d.      T

 

 

33.    Isoniazid:

 

a.      T

b.      T

c.      T

d.      T

 

 

34.    Rifampicin:

 

a.      T

b.      T

c.      F

d.      T

 

 

35.    Ethambutol:

 

a.      T

b.      F

c.      T

d.      T

 

 

36.    Tetracyclines:

 

a.      T

b.      T

c.      T

d.      F

 

 

37.    Cyclophosphamide:

 

a.      T: other indications are chronic lymphocytic leukaemia, multiple myeloma, sarcomas and carcinomas of breast, lung and ovary.

b.      F: add an alkyl group to nucleophilic components of cells causing abnormal base pairing or strand scission.

c.      T

d.      T

 

 

38.    The following alkylaing agents can be administered orally:

 

a.      T

b.      T

c.      T

d.      F: can cause tissue necrosis.

 

 

39.     Sulfamethoxazole:

 

a.      T

b.      T

c.      T

d.      T

 

 

40.    Metronidazole:

 

a.      F: well absorbed orally.

b.      F: bactericidal in vitro for many anaerobic bacteria.

c.      F: diffuses well into all tissues and fluids including the CNS.

d.      T

 

 

 

 

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