Pharmacology of the Cardiovascular and Central Nervous Systems

51.    Benzhexol:

a.     is an anti-cholinergic drug.

b.     is used to treat Parkinsonism.

c.     decrease intra-ocular pressure. 

d.     increase salivation.

52.    The MAO inhibitors cause:

a.     salivation.

b.     blurred vision.

c.     tremor.

d.     hepatocellular necrosis.

53.    Drug interactions may occur between imipramine and:

a.     adrenaline.

b.     guanethidine.

c.     cimetidine.

d.     phenobarbitone. 

54.   Among the benzodiazepine group of compounds:

a.      flurazepam is less likely than triazolam to cause hangover effects.

b.      anti-convulsive potency of clonazepam is greater than temazepam.

c.      chlordiazepoxide, medazepam and chlorazepate have a common metabolite.

d.      diazepam is absorbed more rapidly than oxazepam after oral administration.

55.    Compared to phenobarbitone, thiopentone:

a.      is more rapidly distributed to the brain.

b.      causes mydriasis.

c.      decreases uterine tone during labor.

d.      stimulates the defecation reflex.

56.    Pharmacological responses to opioids include:

a.      warm and flushed skin.

b.      mydriasis.

c.      decreased uterine tone during labor.

d.      stimulates the defecation reflex.

57.    Morphine:

a.      acts on opioid receptors on the dorsolateral horn of the spinal cord.

b.      normally causes hypertension at therapeutic doses.

c.      has a duration of action of 3 - 5h.

d.      is more potent than buprenorphine.

58.    Diazepam:

a.      has a high therapeutic index.

b.      is a GABA receptor agonist.

c.      possesses anti-convulsant activity.

d.      has a short half-life.

59.    Verapamil:

a.      is well absorbed.

b.      has poor systemic availability when taken orally.

c.      decreases left ventricular function.

d.      excreted mainly unchanged by the body.

60.    Nifedipine:

a.      reduce tone of vascular smooth muscle.

b.      reduce force of contraction on myocardium.

c.      reduce AV nodal conduction.

d.      reduce autorhythmicity of SA node.

<< Last Page                       Answers                             Next Page >>