Pharmacology of the Cardiovascular and Central Nervous Systems
51. Benzhexol:
a. T
b. T: particularly useful for tremor and rigidity.
c. F: being an anti-cholinergic, it causes mydriasis with a consequent increase in intraocular pressure.
d. F: dry mouth is a common side effect.
52. The MAO inhibitors cause:
a. F
b. T
c. T
d. T
53. Drug interactions may occur between imipramine and:
a. T: increased adrenergic transmission.
b. T
c. T: cimetidine is an enzyme inhibitor.
d. T: phenobarbitone is an enzyme inducer.
54. Among the benzodiazepine group of compounds:
a. F: flurazepam is metabolized to oxazepam with a half-life of 80h while triazolam has a half-life of 3h.
b. T
c. T
d. T
55. Compared to phenobarbitone, thiopentone:
a. T
b. F
c. F
d. F
56. Pharmacological responses to opioids include:
a. T: due to cutaneous vasodilation.
b. F: causes miosis.
c. T
d. F: causes constipation.
57. Morphine:
a. T
b. F
c. T
d. F: buprenorphine is a semi-synthetic opioid having a potency 30x that of morphine.
58. Diazepam:
a. T
b. F: binds to different site on GABA receptor causing increased in opening frequency of chloride channels.
c. T
d. F: has a long half-life of 30h.
59. Verapamil:
a. T
b. T: has an oral bioavailability of 60%.
c. T
d. F: extensively metabolized by the liver.
60. Nifedipine:
a. T
b. F
c. F
d. F