Pharmacology of the Cardiovascular and Central Nervous Systems
61. An acute attack of angina should be treated with:
a. T
b. F
c. F
d. F: for nocturnal angina.
62. The following drugs decrease conduction in the Bundle of His:
a. T
b. F
c. F
d. T
63. Quinidine:
a. T
b. F: increases QT interval.
c. F
d. T: antimuscarinic actions enhance AV conduction and increase heart rate.
64. The characteristic ECG changes produced by cardiac glycosides:
a. T
b. T
c. T
d. F: inversion of T wave.
65. Digoxin increases:
a. F
b. T
c. F
d. T
66. Sodium nitroprusside:
a. F: dilates both arterioles and venules.
b. F: acts within 5min.
c. T: short half-life of 5min.
d. T
67. Clonidine:
a. F: half-life of 6h.
b. F: acts on central alpha2 receptors to decrease sympathetic outflow.
c. T
d. F: causes rebound hypertension in 50% of cases.
68. Hydralazine:
a. F: mainly a arteriodilator.
b. T
c. T
d. F
69. Digoxin:
a. T: excreted mainly unchanged.
b. F: digoxin has a half-life of 40h compared to digitoxin's 168h.
c. F: poor solubility, only 70% of an oral dose is absorbed.
d. F: digoxin increases intracellular stores of calcium; calcium will potentiate its action.
70. The effect of digoxin on the myocardium is enhanced by:
a. F
b. T
c. F: negative inotropic effects on myocardium decreases strength of contractibility.
d. F: antimuscarinic effects increases heart rate.