Pharmacology of the Cardiovascular and Central Nervous Systems
21. Phenytoin:
a. T
b. F: should not be given i.m. as the pH of the solution has to be high to render it soluble.
c. T
d. T
22. Sodium valproate:
a. T: if administered together with clonazepam.
b. T
c. T
d. T: by inhibiting GABA transaminase.
23. The pharmacological effects of morphine include:
a. T
b. T
c. T
d. F: stimulates the synthesis of ADH.
24. Enkephalins:
a. T
b. T
c. T
d. F: endogenous peptides with opioid-like activity.
25. Naloxone:
a. F
b. T: usually given i.v. due to its high systemic first-pass.
c. T
d. F
26. The tricyclic antidepressants:
a. T
b. T
c. T
d. F: oral contraceptives inhibit the metabolism of imipramine.
27. Digoxin can produce the following effects:
a. T
b. T
c. F: decreases QT interval.
d. T
28. Digoxin:
a. T
b. F
c. F
d. F
29. The following drugs increase myocardial excitability:
a. T
b. F
c. F
d. F
30. Procainamide:
a. F: 50 - 70% metabolized by the liver; procaine is metabolized by pseudocholinesterase.
b. F: it is a class IA anti-arrhythmic.
c. T: by impeding conduction of impulses.
d. T