

Jackie:You were much loved and revered. A true testimony to your influence is how your best friends have slipped further out on the edge since your passing (Note this Web site!). I know that Jon and Deirdre miss you lots and lots - no other cat can take your place. Look down now and then and send some wise vibs their way.'Cousin' Debbie
The parathyroid glands maintain a balance of phosphorus and calcium levels. During Chronic Renal Failure, high levels of phosphorus accumulate in the blood (hyperphosphatemia) because the kidneys can no longer efficiently excrete it. When phosphorus is excessive, the parathyroid glands produce more of the parathyroid hormone (PTH) in an attempt to restore a calcium/phosphorus balance. The overproduction of PTH results in calcium being removed from the bones to balance the excess phosphorus.
PTH is a protein hormone secreted by the parathyroid gland which is the most important regulator of body calcium and phosphorus.
PTH
increases the calcium and phosphorus release from bone
decreases the
loss of calcium and increases the loss of phosphorus in the
urine
increases the activation of 25-hydroxy Vitamin D to 1,25-dihydroxy
Vitamin D in the kidneys
Secretion of PTH is regulated by the level of calcium in the blood. Low serum calcium causes increased PTH to be secreted, whereas increased serum calcium inhibits PTH release.
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Table Of Contents........Jackie As A Kitten........Jackie As An Adult
Jackie - Her Last Weeks......E Mails On Jackie - The CRF Mailing List........Links
