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Perimenopause Naturally: An Integrative Medicine Approach by Tori Hudson, N.D. Perimenopause: signs and symptoms Individual assessments and recommendations Principles of naturopathic medicine Natural therapies for perimenopause: the scientific facts There is a growing body of scientific evidence to assess the efficacy of natural therapies for perimenopausal symptoms and disease prevention. Here is a brief summary of what the studies tell us so far: Phytoestrogen Plants manufacture thousands of chemical compounds vital to the health and function of the plant. Those chemical compounds, generally known as micronutrients, are consumed by humans whenever the plants are eaten. One class of chemical compounds manufactured by plants is known as phytoestrogens. Over 300 plants contain phytoestrogen compounds. They comprise a large part of our diet, and are found in medicinal plants as well. There are several sub-classifications of phytoestrogens, including the category known as isoflavones, to be found in spinach, fruits, clovers, peas, beans, and especially in soy products. Isoflavones are of particular interest to the perimenopausal woman since they have a structure similar to naturally occurring (endogenous) steroidal sex hormones. Isoflavones have the ability to bind to oestrogen receptors on human cells, and in women, they have a preference for binding to the beta form of the oestrogen receptor. As a result, isoflavones preferentially express estrogenic effects in the central nervous system, blood vessels, bone and skin, and they appear to do so without causing stimulation of the breast or uterus.[1] However, in that isoflavones are structurally related to endogenous estrogens, they are able to mimic some of the effects of human oestrogen, but to a significantly lesser degree. It is estimated that soy isoflavones are 1/400th to 1/1000th the potency of the oestrogen estradiol. Uniquely, isoflavones may also act as anti-estrogens, much like "Selective Estrogen Receptor Modulators" (SERMs), synthetic hormones which act selectively as oestrogen on some organs or tissues of the body and as anti-estrogens on others. Isoflavones can be thought of as one of nature's SERMs. Therapeutically, isoflavones may alleviate menopause symptoms, and lower the risk of osteoporosis, coronary artery disease, breast and uterine cancer.[2] Soy Isoflavones Red Clover Isoflavones Botanicals Black Cohosh Combination products Other Botanicals Natural Hormones Conclusion Source(s) Back - Home - Next |