Plot:
In a desolate city, there are no people, just a few bodies in the streets.
In a boarded-up house, Vincent Price awakens to face the day, 3 years after the fall of humanity. He checks on his electrical generator. Finding a few bodies around his house, heads back inside. Vincent tries broadcasting another radio message that just returns static.
On his doors, the mirrors are shattered. The garlic has lost its odor. He heads into the city to get some more garlic. Not yet found the nest where �they� hide during the day. He sharpens a few stakes grabbing them he heads out�
The bodies are loaded into his hearse. Realizing he needs gas, too. The hearse heads out on these empty streets. The bodies along the streets will be cleared later. Refueling from a gas tanker truck, he drives away. Donning a gas mask, he throws the bodies into a burning charnel pit or as I think of it the dump.
In the supermarket, he looks around before getting some garlic. At a mirror store, he gets some new mirrors to replace the broken ones. The hunt begins for vampires. A staking montage ensues. More bodies thrown into the pit montage ensues, too. Vincent heads home.
The garlic wreathes are readied. The doors are barricaded. The sun falls into the horizon and the children of the night walk the Earth. Inside, Vincent has a jazz record playing as the vampires slowly lurch towards his house and try breaking into it. He has to wait through the night. Awakening from a nightmare, he readies more stakes for this new day�
Vincent heads to the cemetery where his wife is interred. Falling asleep and it is dark outside. He rushes past the swarming hordes of vampires and gets to his house. The vampires have begun their nightly assault of the house.
Vampires rush him until he uses a mirror to ward them off. Inside, Vincent begins watching home movies of his wife and daughter. He begins to laugh maniacally before bursting into tears as the vampires continue to attack his house.
Flashback to before the end of the world as we know it�Vincent�s daughter Kathy is celebrating her birthday. Vincent�s friend Ben arrives with an article about an airborne disease that is ravaging Europe. Vincent thinks the disease isn�t as bad as everyone lets on. The germ seems to be unable to be destroyed by any known process.
As a precaution, Vincent has Kathy sleeping under a mosquito net. Virge, his wife, is fixing breakfast. She is starting to come down with the disease herself, but hiding it from Vincent. The lab where Vincent and Ben are working is frantically searching for a cure.
Ben is telling stories that the bodies are being burnt because the dead are returning. Vincent doubts these stories. That night, on the news, the dead bodies are to be burnt according to a national emergency. Kathy is getting sicker. Vincent doesn�t want a doctor called for the plague infected Kathy. He orders Virge not to call a doctor. The doctor would be required to report Kathy�s disease. Vincent heads back to the lab.
As he�s leaving, he spots a military truck carrying out the body of a neighbor child to be burnt. He stops to pick up Ben. Ben has a garlic wreath on his door. Ben wants Vincent to leave him alone. Ben seems to be 1 conspiracy theory shy of total paranoia.
Vincent heads to the lab, passing a military convoy. At the lab, only Dr. Mercer remains. They get to work, there must be a cure.
That night, a military truck pulls away as Vincent arrives. Kathy is gone. Virge called a doctor. Vincent rushes to the charnel pit trying to find Kathy�s body. The army stops him as more and more bodies are tossed into the makeshift crematorium.
The next day, he learns Virge is sick, too. Virge dies. He won�t let her be taken to the pit. Loads her in the car and drives to a field and secretly buries her. That night, he hears a noise and finds the zombie-like Virge returning. The flashback ends and the vampires keep attacking the house.
The next day, Vincent�s car has bee demolished, it was left out and attacked by the vampires. Vincent heads out to find a new car hearse like a station wagon. A dog walks by him. He chases after the dog which runs off. He keeps looking for it and stumbles across some vampires that have been staked but not his handiwork.
At home, he uses his radio again, still no answer. The dog followed him. Vincent welcomes him with open arms. Vampires attack the house while he cleans the dog which is scared of the vampires.
Vincent checks a blood sample and the next thing he buries a small thing about the size of the dog. He spots a girl that runs from him, an actual human out in the daylight. Finally catching up with her, he is about to leave her when she follows him.
Back at his house, Ruth is looking around. Vincent fixes her some coffee. They have some small talk about their lives before in the long, long ago time. Vincent learns she can�t tolerate garlic. She is infected.
Ruth wants to leave but, he fixes her some dinner. The vampires attack the house again. Vincent talks about how he will eventually stake the vampire leader, Ben, his friend.
Vincent talks about why he�s immune to the plague. He was bitten a vampire bat, infected with the disease which was weakened by the bat�s immune system, in Panama. Ruth is getting sicker about to take an injection which retards the germs growth.
A number of people use this injection. He demands the truth. Ruth�s group hunt vampires and the greatest monster of them all, Vincent. The group is going to kill Vincent tonight. Ruth has a gun but passes out.
He ponders what to do. Ruth is given a transfusion and awakens to learn she is cured. The rest of Ruth�s group can be cured. She is now determined to warn the group about his discovery. The vampires realize the garlic normally placed on the door is now gone. Vampires break into the house. Vincent saves Ruth from vampire Ben. Cars approach. The occupants wipe out the vampires
Ruth warns Vincent to escape. Ruth tries telling the group about Vincent�s cure but, they neither hear nor care about it.
Vincent is being chased. A gunfight ensues. He manages to make it to the police armory and escapes to another room. Using some smoke grenades, he escapes to a nearby church and is wounded. The black clad pseudo vampires are searching for him.
Vincent is surrounded. Ruth tries telling them of the cure. He gives a speech about being the last man on Earth and how they are freaks. He is harpooned for such a comment. Ruth rushes to his side as he dies. She walks away, knowing they are all safe now.
