Research Interest:
Svetlana, Razorilova, BS student, Kyrgyz State National University (Bishkek, Kyrgyz Republic)
My research interest is "Human Genes and Drug-effectivness"
It is now clear that much individuality in drug response is inherited: this genetically determined variability in drug response defines the research area known as pharmacogenetics. This article discusses the potential of pharmacogenetic testing to improve both the efficacy and safety of drug prescribing. The human genome and polymorphism, pharmacogenetic research has gained enormous momentum, with recent advances in molecular genetics and genome sequencing. This is due to the emergence of technologies that permit rapid screening for specific polymorphisms, as well as our recently gained knowledge of the genetic sequences of target genes, and other types of receptors involved in drug response ?s information for the pharmaceutical industry on drugs in development. Genetic information is likely to transform the practice of clinical medicine. Genetics will provide a taxonomy of disease that is based on biochemical mechanisms rather than phenotype. Genetic information will be used to identify individuals who are likely to respond to or suffer toxicity from drugs. Genetic variation will be another form of �risk factor� and will permit early treatment and directed screening. However, there is increasing evidence that pharmacogenetics will be extremely important in the health service. |
