http://www.nzum.com - Botry Zen Ltd

Botry-Zen Limited

Registered Office Address
156 Frederick Street
Dunedin

Directors
SHEPHERD, Maxwell Gilbert
PATERSON, Howard
HUNG, Cheung-Tak

History
Incorporated: 04-APR-2001

Major Shareholders University of Otago - 20% Shares on Issue Ownership Restrictions None Known Share Registry Unknown Website http://home.xtra.co.nz/hosts/botryzen/ News ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 7th June 2002 - NBR Personal Investor, by Chris Hutching RIVALS NIP AT BOTRY-ZEN'S HEELS The promoters of Botry-Zen are pushing ahead with a Stock Exchange listing and more field trials to stay ahead of competitors also close to commercial production of anti-botrytis agents. The latest proposal to Botry-Zen shareholders is for a July listing - a delay on the listing date announced last year of February due to hitches in production and application trials. Investors clearly had high expectations when they massively over-subscribed the $5 million Botry-Zen float by southern businessman Howard Paterson last year by about $115 million. The Botry-Zen organic control agent includes an active organism that out-competes the botrytis fungal infection and can be used on a wide range of crops and particularly grapes. But Botry-Zen is competing in a race against other serious contenders to provide an anti-botrytis solution for the wine and horticulture industry. Listed Certified Organics has two years of northern hemisphere trials under its belt and plans for field trials in New Zealand next year for its organic, microbial fermentation formulation that controls fruit rots, including botrytis and grape sour rot. Certified Organics has already established a distribution chain for its products in New Zealand, has appointed agents in Australia, and is in the process of setting up joint ventures internationally to market and distribute its products. The company has struck a licensing agreement to commercialise the product being developed by its partner, BioDiscovery, and the companies will collaborate to develop other organic biopesticides, fungicides and herbicides. The company's biological botrytis control is thought to work by altering the levels of naturally occurring favourable populations of bacteria and fungi on the plant, reducing the incidence of unfavourable micro organisms. Certified Organics managing director Dr Earl Stevens said Botry-Zen might have a profile advantage in the investment market because it had been developed closely in conjunction with the wine industry and HortResearch but the business plan appeared to hinge on cornering a significant portion of the market. He questioned the vulnerability of a single-product company and the purpose of listing on the Stock Exchange at such an early stage in its commercialisation. Certified Organics would be launching on to the market its own home garden range of natural weed killers based on pine extract this Spring. Dr Earl said while his company competed with Botry-Zen, it was pleasing to see entrepreneurs like Mr Paterson raise the profile of New Zealand's bio-technology industry. He said botrytis was estimated to cost the New Zealand wine industry some $18 million a year in lost production and control measures, and the kiwifruit industry $20 million. The most common control method is to spray crops with chemical fungicides that plants may develop resistance to and which consumers distrust. Meanwhile, Botry-Zen chairman Dr Max Shepherd said in a letter to shareholders that they will be asked to approve a new constitution at a special general meeting in Dunedin on June 19. In a letter to shareholders he outlined recent problems that have been overcome. Previously Botry-Zen had been embodied in a liquid suspension, which was susceptible to a wide fluctuation in temperature during transit and also to variations depending on the end users' storage and application techniques. This had led to variations in product concentration and some technical difficulties in application. Despite this, field trials during the past season have again produced pleasing results, with the Botry-Zen product controlling botrytis infections in Gisborne, Hawke's Bay and Marlborough. The product is now produced as a paste which has solved the early inconsistencies and lengthened the shelf life to many months, according to Botry-Zen CEO John Scandrett. ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ Press Release by Botry-Zen at 28 May 2002 12:50 Botry-Zen Ltd, the company pioneering the international launch and commercialisation of an organic control for Botrytis fungal infections in a wide range of crops, but particularly in grapes, is expecting to list on the main board of the New Zealand Stock Exchange in July. Shareholders will be asked to approve the adoption of a new constitution, which complies with NZSE listing rules, at a special general meeting in Dunedin on June 19, according to chairman Dr Max Shepherd. The company had expected to list earlier this year but this had been delayed for a number of reasons, "including investigations as to whether it might be more appropriate to list the company on a foreign Stock Exchange. Having carefully reviewed all aspects of this opportunity, the directors have decided to proceed without further delay with an NZSE listing". In a newsletter to shareholders, Dr Shepherd says that following some teething problems with last seasons' trials, the company has refined its manufacturing process. Previously Botry-Zen had been embodied in a liquid suspension, which was susceptible to a wide fluctuation in temperature during transit and also to variations depending on the end users' storage and application techniques. This had led to variations in product concentration and some technical difficulties in application, problems that have now been remedied through improvements in the manufacturing process. Despite this, field trials during the past season have again produced pleasing results with the Botry-Zen product controlling Botrytis infections in Gisborne, Hawkes Bay and Marlborough regions. "The results achieved are typical and illustrate the effectiveness of Botry-Zen" Dr Shepherd says. Commenting on the improved manufacturing process, Botry-Zen chief Executive Mr John Scandrett said today, "the successful development of the paste by our Research and Development team is the most significant step in the company's history to date. It has enabled us to solve the early product inconsistencies experienced in the trials and most significantly; we have taken the product shelf life from several weeks to many months. "This will enable the company to manufacture for 12 months of the year rather than over a 26 week cycle and as a consequence we can seriously plan to supply Northern Hemisphere markets in an export capacity as opposed to the off-shore manufacturing licensing options considered previously". The company is moving quickly to expand the Dunedin plant and currently an investment of $700,000 is underway for plant improvements over the next three months. Employee numbers will increase from 12 at present to over 20, Mr Scandrett said. Dr Shepherd describes Botry-Zen as a "clean green biological control product", and notes that the directors of the company remain confident that Botry-Zen "is a world leading product with global earnings prospects". Annual accounts for the year ended March 31 2002 are presently with the auditors and will be circulated along with a notice of annual meeting once the audit process is complete. ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ Friday 17th May 2002 - NBR Personal Investor, by Deborah Hill Cone New Botry-Zen chief executive John Scandrett says the company has successfully developed a "new format" of its grape-rot product, in response to a teething problem revealed in trials. The trials exposed some problems with the liquid suspension formulation of Botry-Zen because of the tight time-frame in which it must be transported to vineyards. It has a short shelf life and does not travel well, Mr Scandrett says. But this has been overcome by developing a different product "format" from the liquid suspension formulation. The product will still be applied by spraying on to the vines. "As with any new product there have been some hiccups but we were still able to get the product on to the vines and demonstrate it worked and worked well." Mr Scandrett says he cannot reveal details of the new format as it may represent new intellectual property (IP) and is going through the patent process. The opportunity to get a patent can be lost if details of the IP are released into the public domain. But Mr Scandrett says the company is very pleased with the results of the trials, in which 60 winegrowers took part. "We have a high level of faith in the product." Bunch rot caused by botrytis cinerea has been estimated to cost the local wine and grape-growing industry $30 million in lost sales and the cost of control measures. Botry-Zen is a non-pathogenic fungus, which acts as a biological control agent by competing for the same niche as botrytis cinerea. Mr Scandrett says the tests show when Botry-Zen is "applied correctly and in a timely fashion" it is on a comparative basis with traditional chemical fungicides. Botry-Zen has invested $600,000 in setting up production facilities in Dunedin. It is now looking at manufacturing the product there to be distributed worldwide, rather than selling the licence for others to manufacture it in overseas markets. The company has been talking to prospective manufacturers in France and South Africa. "But now we potentially have a totally new export market," Mr Scandrett says. There are 12,200ha of grapes planted in New Zealand and this coming season Botry-Zen hopes 3000-4000ha will use its biological control agent product to deal with botrytis. Different areas are affected by botrytis to different degrees - high-pressure or low-pressure botrytis - depending on the weather conditions, with varying amounts of spraying needed to keep it under control. Mr Scandrett joined Botry-Zen over a month ago after a 12-year career with the University of Otago where he was involved in negotiating deals to commercialise IP created through university research. Botry-Zen is pushing ahead with plans to list the company next month. After having a provisional licence to carry out trials, it is waiting on registration of product under the Agricultural Compounds and Veterinary Medicines Act. ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 19.02.02 - NZUM The Chief Executive of Botry Zen, John Scandrett, has been issued 1,000,000 options in lieu of part of his cash renumeration. The options are exercisable during the period from 7 March 2003 to 7 March 2007 at Mr Scandrett's discretion provided that the annualised returns to shareholders from 7 February 2002 until the exercise date is greater than 10%. Each option confers a right to be issued one Ordinary Share at an exercise price of 40c. ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ Friday 17th August 2001 - NBR Personal Investor, By Chris Hutching The Midas touch of South Island entrepreneur Howard Paterson was at work again when investors sent cheques worth nearly $120 million for a $5 million share issue to float a biotechnology company. Mr Paterson confirmed yesterday all the cheques were genuine and had been cleared by the bank but most of the money is being sent back, with the successful subscribers receiving about 4% of what they applied for. Some investors sent in cheques for many millions of dollars. The chosen few who received an allocation in Botry-Zen, which has developed an organic agent to control botrytis in grapes, are mainly New Zealand investors but there are some overseas interests whose involvement will be valuable when the company sets up international distribution. The shares, issued at 10c each, made their trading debut on the secondary board of the Stock Exchange at 50c each before settling back to 33c mid-week. Mr Paterson said, compared with some other floats, Botry-Zen offered a real product backed with research from reputable organisations as well as the industry. Investors clearly had made decisions based on the credibility and track record of the parties involved. Another attraction for investors was the perception that when good looking floats came on the market the sharebroking firms snapped them up while floats with lesser prospects tended to get offloaded fairly quickly to clients. Mr Paterson's modus operandi was also evident in the recent floats of Blis and A2 Corporation owners of patents for health products that are still being developed. A select few investors are invited to subscribe at 10c a share and, when share trading begins, the price tends to skyrocket. In the case of Blis a subsequent share issue for more working capital was made at 73c a share and by the time the shares eventually listed on the main board of the Stock Exchange the price soared to $2.20 before settling back to current prices at around 90c. One of the people who helps Mr Paterson in his Dunedin office at the Edinburgh Trust (not a registered company) is David Parker, who said only those who were invited to take part in the initial issue of Botry-Zen received a scaled back allocation. But many more had sent in cheques unsolicited in the hope they would receive a parcel. Once they were trading on the market, prices were based on expectations about the potential value of the intellectual property involved, he said. "It's the track record of Howard and the Edinburgh Trust that drives these things. He has a loyal group of colleagues and friends who can provide the necessary capital to help get things off the ground. But buyers estimate what the potential is and discount it by about 90% to arrive at what they think is a fair price for the shares," he said. "In the case of Blis, we had the initial float and then a placement to institutions before final Stock Exchange listing. The share price eventually settled back to about what it was during the interim phase, which suggests to me that fair value had been factored in by those institutions, who also give credibility that the company has potential. "What's more difficult is to value these fledgling companies at the very start but we take extreme care not to manipulate prices and instead let the free market reign." Mr Parker said Botry-Zen's anti-fungal product for grape vines would reach the product selling stage before Blis, which required more capital for further research and commercialising the product. "We have a lot of people come to us who own intellectual property because they want the lowest risk outcome. Howard generally rejects nine out of 10 proposals and in the case of Blis other people had a look at the proposal and turned it down," he said. ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ Friday 27th July 2001 - NBR Personal Investor, by Chris Hutching A third biotechnology company is being launched by Dunedin entrepreneur Howard Paterson at the same time as his Blis Technology company is listed on the Stock Exchange. Blis arrives on the local bourse on Monday and is commercialising research that prevents a range of serious infections like streptococcal throat. Another biotech company, A2 (NBR, July 20) is also due for listing soon. The new company, which also has plans for eventual listing, is Botry-Zen and a prospectus is in the process of being registered. A site has been bought in Dunedin for manufacturing The key people are Mr Paterson and former University of Otago biology Professor Max Shepherd, whose Dunedin company Zenith Technology Corporation conducts clinical trials and develops, manufactures and markets animal health products. The technology discovery is a biological control agent that prevents bunch rot in grapes. This is a major problem for the wine industry, costing $18 million a year in sales and $12 million a year to control. The disease is also known as noble rot and grey mould and is arguably the biggest disease problem confronting the international wine industry. One of the main attractions of Botry-Zen is that it is organic rather than chemical-based and controls botrytis without affecting the plant. The Wine Institute, which is a research partner in the venture, believes the cost savings just to the local industry will be considerable and immediate. Research was undertaken by HortResearch as part of the Winegrowers of New Zealand research programme, which is jointly funded by the Wine Institute and the New Zealand Grapegrowers Council. It was facilitated by support from the Foundation of Science, Research and Technology, through Technology New Zealand. Laboratory tests and field trials by HortResearch have shown the biological control agent is effective against Botrytis cinerea and successful field trials have been undertaken between 1997 and 2000 in selected vineyards in Hawke's Bay, Gisborne and Marlborough. The botrytis discovery may also help Mr Paterson with his development plans for 2000ha of grape plantings in the Waitaki Valley east of Kurow. Trial plantings have begun. Meanwhile, Blis recently raised $6 million from institutions, placing 8.25 million shares at 73c each. The money will be used to develop Salivaricin B products and other bacteria-fighting substances from the large group identified by Professor John Tagg, of the University of Otago. The university is Blis' biggest single shareholder with 20%. ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

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