IC or "non-bacterial cystitis" is known as an immune system breakdown disorder because it typically appears when immunity has been compromised. In IC, the space between the bladder lining and the bladder muscle is chronically inflamed, leading to pain, sometimes severe. Cracks in the bladder wall allow urine to irritate bladder tissue, leading to a breakdown in the lining of the bladder.
Endometriosis frequently accompanies IC, as does chronic fatigue syndrome, fibromyalgia, irritable bowel syndrome and valvodynia. IC does not respond to antibiotics, and may be aggravated by drug treatments. |