Natural Science Corporation of America
Cogni-NormTM

Cogni-Norm
TM is a unique combination of herbal and nutritional supplements aimed at supporting optimal cognitive function and central nervous system (CNS) health.*

The herbal and nutritional ingredients in Cogni-NormTM are in the amounts shown to be beneficial in scientific studies. The key ingredient is a standardized herbal extract from the leaves of Ginkgo biloba.

The most commonly recommended phytomedicine in Europe, Ginkgo biloba extract (GBE) has been shown to improve cognitive function.* Notable in scientific studies has been an increase in alpha wave activity with a decrease in theta wave activity. GBE has also been shown to support healthy circulation to the brain as well as extremities.* GBE's active constituents include the terpene lactones (ginkgolides and bilobalide) as well as the ginkgo flavone glycosides (flavo-noids like quercetin, kaempferol and isorhamnetin). The terpene lactones are associated with improving circulatory perfusion, microcirculation, and the rheological properties of the blood.* They are also noted for their neuroprotective properties and ability to inhibit platelet-activating factor.* The ginkgo flavone glycosides provide GBE with potent antiradical activity and mildly inhibit platelet aggregation.*

Cogni-NormTM provides GBE in the amount proven beneficial in scientific studies. Other key ingredients in Cogni-NormTM are docosahexanoic acid, vitamins B-1, B-2, B-3, B-5, B-6, B-12, E, and folic acid. Docosahexanoic acid (DHA) is a long-chain polyunsaturated fatty acid classified as an omega-3 essential fatty acid. DHA is a principal structural component in neurological tissues like the brain and retina. DHA is critical for neurological and cognitive development in infants and has also been shown to be an important consideration in cognitive function in the elderly.* DHA is an essential component of brain phospholipids like phostatidylserine (PS). In fact, DHA comprises approximately 30% of the PS in the grey matter of the brain. It is interesting to note that PS supplements being sold in this country are largely devoid of DHA, making their effect of cognitive function questionable. NSCA uses a vegetarian source of DHA derived from marine microalgae.

Vitamins B-1, B-6, and B-12 are essential nutrients for support of cognitive function and other neurological functions in the body.* This is particularly true in elderly individuals who often have a deficient dietary or supplemental intake of these nutrients. To achieve a proper balance of important B vitamins, NSCA has also added vitamins B-2, B-3, and B-5 to Cogni-Norm TM.
Age-related cognitive decline has been partially linked to free radicals in the CNS causing lipid peroxidation and degeneration of neurons. Vitamin E provides antiradical activity that helps protect neurons from peroxidative damage.*

Recommended Use

Take one caplet twice daily with meals. Although benefits should be noted within six to eight weeks, this recommended schedule should optimally be followed for six months. After six months, the daily intake may be reduced to one caplet daily with meals. Cogni-Norm is recommended for long term use as part of a daily supplement regime. The lower intake may also be used as part of a comprehensive wellness program for support of cognitive function.

Contraindications, adverse reactions or interactions
Side effects due to any of the ingredients in Cogni-Norm are rare. Mild gastrointestinal upset and mild, transient headache have been reported in some persons using GBE. There are no known contraindications to the long term use of the ingredients in Cogni-Norm and no known interactions with commonly prescribed medications.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
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