General - risks, definition of NHRT | Which OHT? | Deciding on it | Getting off it | "Natural" hormones | Long term considerations |
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Authors retain copyright and responsibility for content Natural progesterone use for a woman with breast cancer The controversy about natural progesterone creme "It does seem as if [NP cream] is not all the hoo-ha it's supposed to be." "Estrogen dominance" Natural progesterone *does* have side effects Well, my problem is not flashes. I never had them. It's both vaginal changes and impending osteoporosis. Both my gynecologist and my naturopath feel that there is good reason for me to try nat. prog. cream. One of them gave me a prescription that I had filled at a compounding pharmacy. I understand that I can also get compounded prescriptions at Women's' International Pharmacy. What do you all think of them? I use Women's International Pharmacy for my testosterone cream prescription and they are convenient, fast and efficient. They have two national locations and send your meds from the one closest to you. I can set up my account to pay automatically with my credit card and order refills by telephone. This works well for me as I would have to drive across the city to the nearest compounding pharmacist near where I live and that would be very annoying and time consuming. I would expect that any of the mail order pharmacies would work as well. They all provide the same products and price and service are their main competition points. I don't know how others compare for price. As someone who has used NP both in OTC and prescription strength, my experience is that it used to help with certain perimeno symptoms, but now exacerbates them (and it never DID do anything for vaginal irritation/dryness for me). Go figure; obviously my body doesn't want it anymore! (I used it for several years before it started to "go wrong") Re: Dr. Lee - IMO, if something might make you feel better, it is certainly worth a try, but, IMO, I would be cautious assuming that using this would protect you from heart disease or osteoporosis. I have read Dr. Lee's book and he makes what are, IMO, many broad generalizations (one being that NP has "no" side effects - something I and others know from personal experience is patently NOT TRUE. That may be the case for some people, but for others, me included, it can make life miserable). Since I know at least ONE of his statements is untrue, it makes me doubt the BROAD truth of the others; I don't think it's impossible that this can help, but personally I am doubtful it will help everybody and therefore would not feel good about relying on it to do so. I guess if he were more specific and less broad in his comments about this being the thing for all women, I might think his studies worth more. IMO and in my experience, if it sounds to good to be true, it generally is. IMO, weight training and better diet are more proven ways of fighting potential osteoporosis. If the NP causes no bad effects for you, perhaps it will help you - I know women whom it HAS helped with peri/post-meno symptoms; the bone effect is harder to determine. Good luck, but IMO you'd be well served by using other methods of bone building in addition to the NP if you continue to use it.
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If you are going to self treat with OTC progesterone cream at least, please let your doctor know that you are doing it in case you should have a reaction to it. The King's College doctors claim that it isn't well absorbed. Dr. Lee swears that it is, but only shows up in saliva tests and they insist on using blood tests. One day, I am sure we will know the facts. Until we do, it pays to be careful.
At a seminar I attended last night, Dr. John Lee totally dismissed a study about PMS as "just an attempt to sell prozac." He does seem to have a heavy agenda, though, promoting transdermal progesterone (namely Pro-Gest®) and saliva tests (namely from Aeron). Maybe somebody can explain
to me what he was trying to tell me about saliva tests and progesterone.
He says that when you use transdermal progesterone it never appears in
the blood plasma - only in the saliva. When I questioned this because
saliva is a blood filtrate - he said that all the progesterone in the blood
is bound to cell protein. So, if it stays bound in the blood; how
can it get into the saliva? He also used a study from the British Journal
of Cancer which showed women having surgery later in the cycle or having
more serum progesterone having a higher survival rate than those having
surgery earlier in their cycles. His proposal from this was that
it would increase the survival rate of all women having breast cancer surgery
to use natural progesterone cream after surgery. My question is how
can he say this when he just said that you can't measure progesterone in
the blood. Those women weren't using his cream but just had more
endogenous progesterone at the time of surgery - which was measured in
the blood. He couldn't answer my question so that I could understand
it. He just continued to say that his progesterone is passed into
the saliva and the "other progesterone" is bound to cell protein on its
way out of the body through the liver into the bile.
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Anecdote and personal testimony may be adequate for some who wish to experiment with commercial products costing $35 a month along with confirming saliva tests that cost several hundred dollars when these products fail to work as promised, but this may also be considered foolhardy and sham by others. The issue of controversy is only over whether a product market should be driven by personal testimony or scientific fact. And the controversy is when these two marketing features get confused. You presented personal testimony and some of us feel that scientific fact is also required when these commercial products are discussed and/or marketed. And how can one tell who is really posting what on this medium? How do we know your personal story is legitimate or whether you are just trying to sell drugs? We call all look up cited scientific articles and reach our own conclusions, but personal testimony can only stand alone until it is adequately validated. Recently a poster who sells these products finally admitted they didn't do a darn thing for menopausal symptoms while she zealously cried out that we should all try them and charged this need was based upon her reaction to our personalities, and that she had declared anyone who criticized her sales techniques as "hags" in sure need of her wares. What would make a poster react like this over this product? Is this credible marketing of a credible product? If this is not controversial and offensive marketing about sham products, I don't know what more you need to see about this issue. When you have signs and symptoms of menopause that are (1) subjective and (2) episodic, it is very hard to make competent decisions to transfer $35 a month to some stranger for a product that has no science behind it. Why not transfer $35 to yourself and save up for something more fun and worthwhile? Or donate it to a scholarship at your local community college? Why transfer $35 a month for a placebo product unless you think it has some validity? And how do we get that validity? Your personal experience has many holes in it to call it science. First who knows who you are and this is not meant to be an attack but women who sell these products come on all the time with suspect personal testimonies. You are dealing with symptom alleviation that is highly individualistic in any circumstance. There has been shown to be no therapeutic dose in any of these OTC cremes which means that the placebo effect must also be accounted for. Placebo runs as high as 60% for meno effect, why this specific product and why $35 a month for placebo? Why not placebo from something that costs no money? The efficacy of a product validates itself over time and multiple experiences.. You own experience may be short lived but we will never know that unless you choose to report it beyond your first flush of success. And your first flush of success may well be a coincidental variation of symptoms, which would happen no matter what you did or took at this time. No one is ever saying not to try with whatever level of body experimentation you feel comfortable with. But you asked what all the fuss was about a product that is giving you some personal success. I am only providing context for why there is reasonable controversy over the use of this product and the transfer of $35 a month to some stranger for it. Everyone is looking for comfort
and it is good you have found your own. Your personal story is important
and it will be added to the other personal stories of women who have not
found your level of success with use of this product. And in time with
enough responsible and complete stories, we may actually learn something
about it.
Hang in there kiddo. Glad you are still here and reading and posting. I'm glad you have found some help with the NP cream. I am a little confused by what you said about before the surgery. Did you use NP cream to stop the endo? Have you ever heard of anyone having it stop endo other than in Dr. Lee's book? I read the alt.support.endometriosis list and haven't heard anyone post there that it has stopped endo. I have read MLM sales hype testimonials claiming such results, but you can usually recognize these things by the number of exclamation points used in them. Aside from that, you say that NP cream helps your hot flashes. I'm glad for you! There was another poster here who said that it helped her surgical meno hot flashes too; so you are not the first. Maybe it will help you so well that you won't even need to take estrogen and won't need to worry about the estrogen risk factors. Since you are getting good results with the cream, if it's not a prescription cream you are using, you might want to get the prescription kind as it may be less expensive and might be covered by medical insurance and you can get it made stronger. The only risky thing about that is we don't know if there are any long-term risk factors for NP cream. Good old Dr. Lee says it's "perfectly safe" = no risk factors. You just have to ask yourself if you are willing to take his word for it. Fiona |
Quite
a while ago, I'd been seesawing from one hormone treatment to the next
for various reasons, and one of the regimens I was interested in was this
Natural Progesterone. I ordered it from the States through the net, read
Dr Lee's book, (where I come from, there is simply no knowledge of this
method of HRT) and thought ok - lets see. Well, after the first
day even, I really did feel grotty - tired, depressed, bloated and just
generally out of sorts. I persevered, and after about 6 weeks, I
gave it up - it made me feel like a wet rag most of the time.
. I felt terrible throughout those 6 weeks - perhaps I didn't give it enough
time? - who knows.. but I've been doing some reading on it, and it does
seem as if its not all the hoo-ha its supposed to be. YMMV, though.. :)
This is just my personal experience.
Karen M. d'U |
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There have been studies to support the use of progesterone with the term used in the general sense, such as the study I mentioned above. These are not NHRT studies. Jerilynn Prior, an endocrinologist has done some research and is quite enthusiastic about the use of progesterone. She has her own version of the estrogen dominance theory, she calls it "perimenopausal ovarian hyperstimulation". This is of course for women who have ovaries and who have at times too much estrogen. She feels this may be quite common just before menopause and is the cause of heavy bleeding, fibroids, and endo at this time. She does not talk about too little progesterone because progesterone in her opinion as an endocrinologist is only required for reproduction. But she is talking about peri-menopause and your questions on NHRT were on women with a surgical menopause were they not? Are we talking about apples and oranges? Jerilynn Prior feels that women with these estrogen upheavals (or what you seem to call estrogen dominance) should not take any supplementary estrogen until at least 1 year past their final period. This sure makes sense to me. But I don't know if that helps with your question on why do women take HRT. I don't see how a natural estrogen would be any different. Or do you think these women with too much estrogen should take a progesterone to counteract the estrogen? Yes Jerilynn Prior suggests this may help women with severe symptoms. But this is not hormone replacement, this is hormone treatment or therapy. Do you understand the difference? There is certainly not anything natural about it. Either a progestin such as Provera or a natural progesterone such as (in Canada) Prometrium can be used to counter the effects of the estrogen. Either will work. Some would say that the natural progesterone has fewer side effects. I do not know about the women who choose to do HRT. I had so many problems with my hormone levels during peri that adding to the problem by taking supplementary hormones did not make sense to me. Perhaps it would help us
if you describe what you mean by NHRT? I also suggest that you go to tishy's
unofficial webpage and look at the Ovarian Hormone Therapy
page and see why she thinks that OHT is a better way to describe the taking
of supplementary hormones then to use the term HRT. This may
clear up a lot of the misunderstanding some of us are having with the term
NHRT. I just looked at the ng, and see your questions have generated
a lot of response. I hope you do not feel jumped on, this is an issue that
does need to be clarified if we are to understand each other and share
experiences
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Some
Women Cannot Abide Progesterone note: You
may have problems accessing this site using Netscape
Extract fromhttp://members.nbci.com/diff_drummer/index2.html We're up front about this
site being one sided. Some women have bad reactions to progesterone
Don't let this website
convince you that you should not be taking progesterone. And by the same
measure, don't let any mailing lists convince you that you should. Research,
research, research.
To read personal accounts of bad reactions to progesterone, go to http://members.nbci.com/diff_drummer/P-Club/clients.html |
OVARIAN HORMONE THERAPY
General - risks, definition of NHRT | Which OHT? | Deciding on it | Getting off it | "Natural" hormones | Long term considerations |
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