Analgesics, Anti-asthmatics, Endocrine Pharmacology, GIT Pharmacology
11. Aspirin:
a. F
b. T
c. T
d. T
12. The NSAIDs:
a. T
b. F: causes irreversible inhibition of COX.
c. F
d. F: they are highly protein-bound and displace oral anti-diabetics and anticoagulants.
13. Buffered aspirin:
a. F
b. T
c. F
d. F
14. Local anaesthetics used clinically conform to the following basic chemical configuration:
a. T
b. F
c. T
d. F
15. Indomethacin:
a. T
b. T
c. F
d. F
16. Phenylbutazone is:
a. T
b. F
c. T
d. T
17. The following pairs of drugs may cause drug interaction problems:
a. T: aspirin displaces warfarin from binding sites.
b. T: increased CNS sedation.
c. T: guanthidine causes depletion of amines at sympathetic nerve fibers.
d. T: thiazides promote glucose intolerance, probably by interfering with insulin release.
18. Chlorpropamide:
a. F: stimulates the secretion of ADH.
b. T
c. T
d. T
19. Biguanides:
a. F
b. T
c. T
d. F
20. Problems associated with insulin therapy include:
a. T: glucocorticoids enhance glycogenolysis and gluconeogenesis and cause peripheral insulin resistance, thus causing hyperglycaemia.
b. T
c. T: lipoatrophy may occur at sites of subcutaneous injection which would interfere with absorption of insulin.
d. T: oral contraceptives produce peripheral insulin resistance.