Analgesics, Anti-asthmatics, Endocrine Pharmacology, GIT Pharmacology
1. Drugs that are likely to cause Na and water retention include:
a. phenylbutazone.
b. paracetamol.
c. indomethacin.
d. hydrocortisone.
2. Adverse drug reaction caused by antacids include the following:
a. diarrhea by aluminium hydroxide.
b. abdominal distention caused by calcium carbonate.
c. faecal concretion by magnesium trisillicate.
d. gastric acid hypersecretion by sodium bicarbonate.
3. Cimetidine:
a. causes breast soreness.
b. is excreted mainly unchanged by the kidney.
c. is able to suppress basal acid secretion.
d. has significant H1-receptor blocking action.
4. Theophylline:
a. is a derivative of methylxanthine.
b. is useful as a bronchodilator in asthma.
c. acts directly on the beta-receptors in the bronchi.
d. can produce gastric irritation.
5. Prolonged use of corticosteroids as in immunosuppression predisposes to:
a. stunting of growth in children.
b. atrophy of the suprarenal cortex.
c. increased mineralization of bone.
d. hypertrophy of muscle.
6. Problems associated with the use of regular insulin:
a. hypersensitivity reaction.
b. hypoglycaemia.
c. hyperkalaemia.
d. resistance to its action with prolonged use.
7. Chlorpropamide:
a. is excreted mainly in the bile.
b. is a long-acting sulphonylurea.
c. is bound to plasma proteins.
d. does should be reduced in patients with renal failure.
8. Allopurinol:
a. acts by increasing the renal tubular excretion of uric acid.
b. is metabolized to an active metabolite.
c. enhances the breakdown of azathioprine.
d. cannot be given concurrently with colchicine.
9. Lignocaine:
a. is rapidly hydrolyzed by plasma pseudocholinesterase.
b. has a delayed onset of action compared to procaine.
c. can penetrate mucous membrane.
d. can be used to control ventricular tachyarrhythmias.
10. Procaine:
a. is a useful surface anaesthetic.
b. level might be elevated in genetic deficiency of pseudocholinesterase.
c. causes convulsions in high doses.
d. can be used for infiltration anaesthesia.