Pharmacology of the Cardiovascular and Central Nervous Systems

91.    Blood in a test-tube does not coagulate in the presence of:

a.     disodium EDTA.

b.     warfarin.

c.     aspirin. 

d.     heparin.

92.    Addition of potassium citrate to change urinary pH favors the excretion of:

a.     aspirin.

b.     phenobarbitone.

c.     atropine.

d.     morphine.

93.    The drugs for treating Parkinsonism are:

a.     benzotropine.

b.     bromocriptine.

c.     chlorpromazine.

d.     amphetamine.

94.   Drugs with antidepressant action are:

a.      imipramine.

b.      mianserin.

c.      phenelzine.

d.      thioridazine.

95.    Drugs that cause sedation:

a.      morphine.

b.      imipramine.

c.      diphenylhydrazine.

d.      benztropine.

96.    Diazepam can be used for:

a.      epilepsy.

b.      insomnia.

c.      schizophrenia.

d.      alcohol withdrawal syndrome.

97.    The following are mechanisms of drugs indicated with regard to its action:

a.      chlordiazepoxide: potentiate action of GABA.

b.      chlorpromazine: inhibits noradrenaline uptake.

c.      L-dopa: increases brain dopamine synthesis.

d.      bromocriptine: competitive antagonist of dopaminergic receptors. 

98.    A partial agonist on the same receptor as a pure agonist:

a.      will not produce the same maximum response as pure agonist.

b.      will decrease maximum response of pure agonist.

c.      will decrease response to pure agonist when both drugs are present in high concentrations.

d.      is a physiological antagonist of pure agonist.

99.    Carbamazepine:

a.      is the drug of choice in absence seizures.

b.      is excreted largely unchanged by the kidneys.

c.      can cause Steven-Johnson syndrome.

d.      increases brain GABA.

100.    The most appropriate drug to use in patient with an acute hypertensive crisis in hospital is:

a.      propranolol.

b.      frusemide.

c.      methyldopa.

d.      nitroprusside.

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