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                  Dr. Shashank Jain

Hepatitis A- Disease and Prevention

Jains Clinic, E-2 Church compound, Sukhdev Vihar, New Delhi-25; India

Tel: Clinic: 011-26922890   Mobile : 9312403074, 9868856511 

E-mail: [email protected]

Vaccination schedule
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'PREVENTION IS BETTER THAN CURE'

VACCINATION

  NATIONAL IMMUNIZATION SCHEDULE

        Age                    Vaccine       

 Birth

 6 weeks

10 weeks

14 weeks

 9 months

16-18 months

 5 years

10 years

16 years

 Pregnant women

BCG, OPV-0

DPT I, OPV-1

DPT 2, OPV-2

DPT 3, OPV-3

Measles.

DPT  booster,OPV-4

DT

TT

TT

TT -2 doses at 4 wks interval

                    

IMMUNIZATION SCHEDULE

( INDIAN ACADEMY OF PEDIATRICS )

              Age                                     Vaccine     

Birth

 6 weeks

10 weeks

14 weeks

18 weeks

22 weeks

26 weeks

 9 months

16-18 months

18 months

 1 year and above

 2 years and above

 5 years

10 years

16 years

Pregnant women

Puberty onwards 

BCG, OPV -1, Hepatitis B-1

OPV -2, DPT- 1, Hepatitis B-2

OPV -3, DPT- 2, Hib-1

OPV -4, DPT- 3,

OPV -5, Hib-2

OPV -6

OPV -7, Hib-3, Hepatitis B-3

Measles

MMR, Hib (booster)

DPT 1st booster, OPV 1st booster

Hepatitis A-1, Chickenpox vaccine

Typhoid Vi, Meningococcal meningitis, Pneumococcal

DPT/DT  2nd booster, OPV 2nd booster

Tetanus Toxoid

Tetanus Toxoid

Tetanus Toxoid -2 doses at 4 wks interval

Rubella (German Measles)

 

NEWER VACCINES

            VACCINE                         SCHEDULE     

Hepatitis A

Hepatitis B

Chickenpox 

Hib (H. Influenza)

Rubella (German Measles)

Typhoid Vi Antigen.

Meningococcal Meningitis

Pneumococcal

0, 6-12 Months ( > 1 year and adults)

0,1, 5 Months.  ( Birth onwards, and adults)

single dose (1-12 years);>12 years 2 doses 6-10 weeks gap 

0, 2, 4 Mo; booster >15 mo (> 2 months of age)

single dose (Puberty onwards, only Girls)

single dose, every 2-3 years (>2 years , adults)

single dose, every 2 years (>2 years , adults)

single dose, every 2 years (>2 years , adults)

 

TYPES OF VACCINES

     Type of antigen                          Examples

  • Live bacteria, attenuated

  • Live virus, attenuated

  • Killed bacteria

  • Killed virus

  • Toxoid

  • Capsular polysaccharide

  • Viral subunit

  • Bacterial subunit

BCG, Ty21a

OPV, Mumps, Measles, Rubella

Pertussis, Salmonella Typhi.

IPV (injectable polio vaccine), Rabies, HAV

DT, TT

Typhoid Vi, Hib, Meningococcal, Pneumococcal 

Hbs Ag

Acellular Pertussis

 

KEY WORDS:

Vaccination: 

Process of inoculating the vaccine/antigen.

Immunization:

 Process of inducing immune response.

Sero Conversion: 

Change from antibody negative state to antibody positive state.

Antibody titer: 

Measures extent of antibody formation after vaccination (reciprocal of highest serum dilution at which antibody  has been detected.)

Geometric mean titer (GMT): 

The mean antibody titer in a group of seroconverted individuals)

Contraindication: 

Strictly not indicated or not to be given.

 

Immunizations

  • Diphtheria, Tetanus, Pertussis, Polio, Measles, Mumps, Rubella, Hemophilus meningitis, and Hepatitis can be killers. 

  • These diseases can all be prevented with immunization. 

  • All infants and children should be completely immunized against these infections. 

  • Adults also need protection against certain diseases like hepatitis A & B, Typhoid, Chickenpox etc. Protect yourself and your family by making sure that everyone is adequately immunized.

 

Before receiving any immunizations, be sure to tell the nurse of doctor if you or your child is allergic to eggs or has a serious illness. Certain vaccines cannot be given during pregnancy or to people who have immune disorders, such as lymphoma, leukemia, and AIDS.

 

Adolescents and young adults

  •   Between 14 and 16 years, immunization against tetanus and diphtheria (DT vaccine) is needed. The DT vaccine is given in three doses for previously vaccinated persons. (Otherwise, a booster is given.) The first and second doses are 8 weeks apart, and the third dose is 6 to 12 months after the second dose. After that, a single DT booster is needed every 10 years.

  • Recent outbreaks of measles among young adults have pointed to the need for revaccination. Colleges and other post-high school educational institutions are now requiring proof of two doses of measles vaccine. Anyone who has not had both doses will need to be vaccinated, either with the MMR vaccine or the measles vaccine.

 

Adults over 25 years

A DT booster is needed every 10 years. People over age 65 years should also be vaccinated against Influenza and pneumonia.

 

People with special risks

Chronic illnesses. 

People with blood clotting diseases (hemophilia) and dialysis patients should be vaccinated against Hepatitis. Vaccines for influenza and pneumonia are recommended for people with any chronic health problem.

Life-style risks. 

Unprotected sex and injection drug use put individuals at high risk for Hepatitis B infection.

Travelers. 

Adult travelers outside the country may need to update their immunizations, particularly Hepatitis, Yellow fever etc.

Immigrants, refugees, and foreign students. 

Many countries do not routinely immunize. As a result, persons entering the country. should be immunized.

Residents of institutions. 

Outbreaks of Hepatitis, TB, Chicken pox, Measles, Typhoid and other infectious diseases can occur in correctional facilities and institutions for the mentally retarded.

 

Side effects of vaccines

  • Vaccines are carefully tested for both effectiveness and safety before they are approved. Some soreness, redness, and swelling at the injection site can be expected with most vaccines. Usually these symptoms are very mild and disappear after 1 or 2 days. 

  • Call the doctor immediately if any of the following symptoms occur after vaccination: Fever of 100o F or more, severe headache, swelling of the mouth and throat, difficulty breathing, wheezing, fainting, or seizures.

 

Immunity

The quality of being insusceptible to or unaffected by a certain disease or state. Kinds of immunity are Active immunity and Passive immunity.

Passive immunity

A  form of immunity from antibodies that are carried through the placenta to a fetus or through a breast substance (colostrums) from a mother to an infant. Passive immunity is also caused by injecting ready made antibodies  (antiserum) for treatment or prevention. Passive immunity is not permanent and does not last as long as active immunity.

Active immunity

A  form of long-term, gained immunity. It protects the body from new infection. 

Immune system

A complex that protects the body from disease organisms and other foreign bodies. The system includes the humoral immune response and the cell-mediated response. The immune system also protects the body from invasion by making local barriers and inflammation. The humoral response and the cell-mediated response develop if these first defenses fail to protect the body. The humoral immune response is especially effective against bacterial and viral invasions. The main organs of the immune response system are the bone marrow, the thymus, and the lymphoid tissues. The system uses other organs, too, as the lymph nodes, the spleen, and the lymphatic vessels. The response may start as soon as the antigen invades or start as long as 48 hours later

Immunization, 

A process by which resistance to an infectious disease is induced or augmented.

 

DTP 

Protects against Diphtheria, Tetanus, and Pertussis. Children need a total of five doses (DTP-1, DTP-2, etc.) before reaching school age.

DT (diphtheria and tetanus) 

Is given after age 14 years.

OPV 

Is oral polio vaccine, and children need a total of seven doses (OPV-1, OPV-2, etc.) before reaching school age.

MMR 

Immunizes against measles, mumps, and rubella. Two doses (MMR-1 and MMR-2) are necessary. 

Hemophilus

Vaccine protects against a type of meningitis that particularly affects children. This vaccine is given in 4 or 3 doses (option 1 or 2, depending on the type of vaccine that is used).

Hepatitis b (HB) 

Vaccine is recommended for infants and any person of any age who is at risk for exposure to hepatitis b. This vaccine is given in a series of 3 or 4 doses (option 1 or 2, depending on the type of vaccine that is used).

BCG 

Vaccine is administered  to protect against tuberculosis (TB). 

Pneumococcal vaccine,

  • An active vaccination drug with foreign bodies (antigens) of the 14 types of Pneumococcus linked to 80% of the cases of Pneumococcal pneumonia.

  • It is given to patients over 2 years of age who are at high risk of getting severe Pneumococcal pneumonia.

 

           

 FOR QUALITY VACCINE AT AFFORDABLE PRICES

 contact Dr. Shashank Jain 

Tel: 011-26922890, Mobile:9312403074; 9868856511

    Email: [email protected]      

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