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Some useful references on Andrographis paniculata
Author(s): Abeysekera AM, De Silva KTD, Silva WSJ, Ratnayake S, Labadie RP
Year: 1988
Address: Not available
Title: Proton and carbon-13 NMR spectral analysis of andrographolide
Source: Fitoterapia 501-504
Notes: The 1H- and 13C-NMR spectra of andrographolide, the major diterpenoid of
Andrographis paniculata, have been recorded and the assignments made using
resonance and broad band decoupled spectra (13C) and the COSY 45 - 2D spectrum
Author(s): Ahmed A, Talukdar SA
Year: 1977
Address: Not available
Title: Not available
Source: Bangladesh Pharm J 6: 21-24
Notes: Not available
Author(s): Aiyar KN, Kolammal M
Year: 1963
Address: Dept Pharmacognosy, University of Kerala, Trivandrum
Title: Pharmacognosy of Ayurvedic drugs Kerala, No. 5
Source: Ind J Pharm 25: 143
Notes: Not "available"
Author(s): Akbarsha MA, Manivannan B
Year: 1993
Address: School of Life Science, Bharathidasan university, Tiruchirapalli 620024
Title: Biochemical changes in the testis and male accessory organs of albino rats on treatment
with Andrographis paniculata (Nees)
Source: Ind J Comp Abim Physiol 11: 103-108
Notes: Not available
Author(s): Akbarsha MA, Manivannan B, Hamid KS, Vijayan B
Year: 1990
Address: PG Dept Zoology, Jamal Mohamed College, Tiruchirapalli 620020
Title: Anti-fertility effect of Andrographis paniculata (Nees) in male albino rat
Source: Ind J of Experimental Biology 28(5): 421-426
Notes: Dry leaf powder of Andrographis paniculata, when fed orally to male albino rats, at a dose
level of 20 mg powder per day for 60 days resulted in cessation of spermatogenesis,
degenerative changes in the seminiferous tubules, regression of Leydig cells and
regressive and/or degenerative changes in the epididymis, seminal vesicle, ventral
prostate and coagulating gland. There was reduction in the weight and fluid content of the
accessory glands, accumulation of glycogen and cholesterol in the testis and increased
activities of lactate dehydrogenase in the testis and alkaline phosphatase in testis and
ventral prostrate. The results suggest antispermatogenic and/or anti-androgenic effect of
the plant.
Author(s): Alagesaboopathi C, Balu S
Year: 1996
Address: Dept of Botany, AVVM Sri Pushpam College, Poondi 613503, Thanjavur, TN, India
Title: Phytochemical observations on some species of Andrographis Wall
Source: Ancient Sci of Life 15: 293-295
Notes: Phytochemical studies of leaf of the herbs Andrographis paniculata, Andrographis alata
and Andrographis lineata (Acanthaceae) were carried out. Presence of Phenolic
compounds, flavanoids, saponins and tannins and absence of steroids and triterpenoids
have been reported here in this herbs for the first time.
Author(s): Ali MA, Mikage M et al
Year: 1991
Address: Not "available"
Title: Screening of crude drugs used in Bangladesh for nematocidal activity on the larva of
Toxicara canis
Source: Shoyakugaku Zasshi 45: 206-214
Notes: Not "available"
Author(s): Allison AJ, Butcher DN, Connolly JD, Overton KH
Year: 1968
Address: Not "available"
Title: Paniculides A, B and C: bisabolenoid lactones from tissue cultures of Andrographis
paniculata
Source: Chem Commun 23: 1493
Notes: Not "available"
Author(s): Aminuddin RD et al
Year: 1993
Address: Not available
Title: Native phytotherapy for child and women diseases from Assam
Source: Ethnobotany 5: 87-91
Notes: Decoction of 10-12 leaves (250 ml) is given once a day to check diarrhea
Author(s): Aminuddin RD, Girach A, Hkan S
Year: 1993
Address: Not available
Title: Treatment of malaria through herbal drugs from Orissa, India
Source: Fitoterpia 64: 545-548
Notes: Not available
Author(s): Aminuddin, Girach RD
Year: 1991
Address: Not available
Title: Ethnobotanical studies on Bondo Tribe of District Koraput (Orissa), India
Source: Ethnobotany 3: 15-19
Notes: Not available
Author(s): Aminuddin, Girach RD
Year: NA
Address: Not available
Title: Not available
Source: J Nat Products 56: 995-999
Notes: Not available
Author(s): Anandan T, Veluchamy G
Year: 1986
Address: Not "available"
Title: Folk-medical claims from Tamil Nadu North Arcot District
Source: Bull Med Ethnobot Res 7: 99-109
Notes: Not "available"
Author(s): Anastasis P et al
Year: 1983
Address: Not "available"
Title: Role of leucine in terpenoid metabolism. Incorporation of 2-(13C) and 3-(13C) leucines
into sesquiterpenoids by tissue cultures of Andrographis paniculata
Source: J Chem Soc, Chem Commun 21: 1189-1191
Notes: Not "available"
Author(s): Anastasis P*, Freer I*, Gilmore C*, Mackie H*, Overton K*, Swanson S^
Year: 1982
Address: *Plant Tissue Culture Unit, Dept of Chemistry, University of Glasgow, Glasgow G12 8QQ,
Title: Cyclisation of fernesyl pyrophosphate to gama-bisabolene in tissue cultures of
Andrographis paniculata
Source: J Chem Soc, Chem Commun, 268-270
Notes: Tissue cultures of Andrographis paniculata transform trans, trans-[1-(3H2); 12,13-(14C2)]
farnesyl pyrophosphate, and (3R, 5R)- and (3R, 5S)-(5-(3H))- mevalonolactones into
Z-gama-bisbolene without tritium loss, the absolute configuration of paniculide B has
been determined by an X-ray crystal structure determination of its bis-p-bromobenzoate.
Author(s): Anastasis P, Freer I, Gilmore C, Mackie H, Overton K, Picken D
Year: 1984
Address: Not "available"
Title: Biosynthesis of gamma bisabolene in tissue cultures of Andrographis paniculata
Source: Canad J Chem 62: 2079-2088
Notes: Not "available"
Author(s): Anastasis P, Freer I, Overton K, Rycroft D, Singh SB
Year: 1985
Address: Plant Tissue Culture Unit, Dept of Chemistry, University of Glasgow, Glasgow G12 8QQ,
Title: The role of lucine in isoprenoid metabolism. Incorporation of [3-(13C)] leucine and of
[2-(3H), 4-(14C)]- beta, beta- dimethylacrylic acid into phytosterols by tissue cultures of
Andrographis paniculata
Source: J Chem Soc, Chem Commun, 148-149
Notes: [3-(13C)] leucine is incorporated into phytosterols by tissue cultures of Andrographis
paniculata by breakdown to acetyl-CoA and its subsequent incorporation via
(3S)-3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) and mevalonic acid; [2-(3H), 4-(14C)]-
beta, beta- dimethylacrylic acid also is not incorporated intact.
Author(s): Balmain A, Connolly JD
Year: 1973
Address: Not "available"
Title: Minor diterpenoid constituents of Andrographis paniculata Nees
Source: J Chem Soc Perkin Trans I,12: 1247-1251
Notes: Not "available"
Author(s): Balu S, Alagesaboothi C
Year: 1993
Address: Dept of Botany, AVVM Sri Pushpam College (Autonomous), Poondi 613503, Thanjavur,
Title: Anti-inflammatory activities of some species of Andrographis Wall.
Source: Ancient Sci Life 13: 180-184
Notes: Not available
Author(s): Balu S, Alagesaboothi C, Elango V
Year: 1993
Address: Not available
Title: Antipyretic activities of some species of Andrographis Wall
Source: Ancient Science of Life 12: 399-402
Notes: Not available
Author(s): Basak BS, Das Gupta DR
Year: 1952
Address: Not available
Title: Not available
Source: Ind J Phys 26: 539
Notes: Not available
Author(s): Basu NM et al
Year: 1947
Address: Not "available"
Title: On the vitamine C and carotene content of several herbs and flowers used in Ayurvedic
system of medicine
Source: J Ind Chem Soc 24: 358-360
Notes: Not "available"
Author(s): Bhaduri K
Year: 1914
Address: Not "available"
Title: Constituents of Andrographis paniculata
Source: Am J Pharm 86: 349-354
Notes: Not "available"
Author(s): Bhalla Np, Sahu TR, Mishra GP, Dakwale RN
Year: NA
Address: Not available
Title: Traditional plant medicines of Sagar district, Madhya Pradesh, India
Source: J Econ Tax Bot 3: 23-32
Notes: The leaves are mashed and applied on body in itches. The juice of the leaves is used in
treatment of fever and colic pain. Else, pea-size pills are prepared from the leaf paste and
taken orally three times daily after food for 2 -3 days. The plant with some other
ingredients is believed to be useful in snakebite
Author(s): Bharadwaj DK, Gupta AK, Ramesh Chand, Jain K
Year: 1981
Address: Not "available"
Title: Synthesis of Andrographis paniculata flavones
Source: Curr Sci 50: 750-753
Notes: Not "available"
Author(s): Bhat VS, Nanavati DD
Year: 1978
Address: Not available
Title: Andrographis paniculata (Burm) Wall ex Nees (Kalmegh)
Source: Indian Drugs 15: 187-190
Notes: A review on the botanical characteristics and habitat, chemistry and tissue cultures of
Andrographis paniculata.
Author(s): Bhatnagar SS
Year: 1961
Address: Not "available"
Title: Biological activity of Indian medicinal plants Part I. Antibacterial, antitubercular and
antifungal action
Source: Ind J Med Res 49: 799
Notes: Not "available"
Author(s): Bhaumik A, Sharma MC
Year: 1993
Address: Div of Experimental Medicine & Surgery, Ind Vet Res Inst, Izatnagar 243122
Title: Therapeutic efficacy of two herbal preparations in induced hepatopathy in sheep.
Source: J Res Educ Ind Med 12: 33-42
Notes: Formulations containing equal parts of Andrographis paniculata, Phyllanthus niruri and
Solanum nigrum was put to therapeutic trial in paracetamol induced hepatopathy in
sheeps. These drugs were given in the doses of 1gm/kg body weight daily, orally in two
divided doses starting from 1st day to 10th day. Treatment of animals showed reversal of
changes.
Author(s): Boorsma WA
Year: 1896
Address: Not "available"
Title: Constituents of Andrographis paniculata
Source: Med's Land Plant 18: 63
Notes: Not "available"
Author(s): Borthakur SK
Year: 1991
Address: Not available
Title: Ethnobotanical studies on Bondo Tribe of district Koraput (Orissa), India
Source: Ethnobotany 3: 15-19
Notes: Not available
Author(s): Borthakur SK
Year: 1992
Address: Dept of Botany, Gauhati University, Guwahati 781014, India
Title: Native phytotherapy for child and women diseases from Assam in northeastern India
Source: Fitoterpia 63: 483-488
Notes: A man of 42 with sore-throat took 8 tablets of chuanxinlian tablet. He developed
generalized pruritus and urticaria of various sizes with flat surface, areolae and clear
margin, and also pharyngeal congestion. He was given anti-inflammatory and antiallergic
therapy. After treatment symptoms were relieved in 3 days. The tablet was made with the
whole plant of Andrographis paniculata (chuanxinlian).
Author(s): Borthakur SK
Year: 1993
Address: Not available
Title: Native phytotherapy for child and women diseases from Assam
Source: Ethnobotany 5: 87-91
Notes: Not available
Author(s): Burgos RA, Caballero EE, Sanchez NS, Schroeder RA, Wikman GK*, Hancke JL
Year: 1997
Address: Facultad de Ciencias Veterinarias, Universidada Austral de Chile, PO Box 567, Valdivia,
Title: Testicular toxicity assessment of Andrographis paniculata dried extract in rats
Source: J Ethnopharmacol 58: 219-224
Notes: The possible testicular toxicity of Andrographis paniculata, standardised dried extract was
evaluated in male Sprague Dawley rats for 60 days. No testicular toxicity was found with
the treatment of 20, 200 and 1000 mg/kg during 60 days as evaluated by reproductive
organ weight, testicular histology, ultrastructural analsysis of Leydig cells and
testosterone levels after 60 days of treatment. It was concluded that Andrographis
paniculata dried extract did not produce subchronic testicular toxicity effect in male rats.
Author(s): Butcher DN, Bowes BG
Year: 1969
Address: Not available
Title: The growth and fine structure of callus cultures derived from Andrographis paniculata
Nees
Source: Z Pflanzenphysiol 61: 385-397
Notes: Not available
Author(s): Butcher DN, Connolly JD
Year: 1971
Address: Not "available"
Title: An investigation of factors which influence the production of abnormal terpenoids by
callus cultures of Andrographis paniculata Nees
Source: J Exp Bot 22: 314-322
Notes: Not "available"
Author(s): Castro IR
Year: 1986
Address: Not "available"
Title: Anatomical studies on some Philippine medicinal plants
Source: Philipp J Sci (Philippines)115: 259-292
Notes: Not "available"
Author(s): Cava MP, Chan WR, Haynes LJ, Johnson LF, Weinstein B
Year: 1962
Address: Not available
Title: Not available
Source: Tetrahedron 18: 397
Notes: Not available
Author(s): Cava MP, Chan WR, Stein RP, Willis CR
Year: 1965
Address: Not available
Title: Not available
Source: Tetrahedron 21: 2617
Notes: Not available
Author(s): Chakravarti D, Chakravarti RN
Year: 1952
Address: Not available
Title: Not available
Source: J Chem Soc 1697
Notes: Not available
Author(s): Chakravarti RN
Year: 1957
Address: Not "available"
Title: Chemical structures of active principles of plants
Source: Bull Calcutta Schi Trop Med 5: 123-124
Notes: Not "available"
Author(s): Chan WR, et al
Year: 1968
Address: Not "available"
Title: Structure of neoandrographolide - a diterpene glucoside from Andrographis paniculata
Nees
Source: Tetrahedron Lett 46: 4803-4806
Notes: Not "available"
Author(s): Chan WR, Haynes LJ
Year: 1960
Address: Not "available"
Title: The structure of Andrographolide
Source: Chem & Ind No.1, 22
Notes: Not "available"
Author(s): Chan WR, Taylor DR, Willis CR, Bodden RL, Fehlhaber HW
Year: 1971
Address: Not available
Title: Not available
Source: Tetrahedron 27: 5081
Notes: Not available
Author(s): Chan WR, Taylor DR, Willis CR, Fehlhaber HW
Year: 1968
Address: Not available
Title: Not available
Source: Tetra Letts 46: 4803
Notes: Not available
Author(s): Chan WR, Willis CR, Cava MP, Stein RP
Year: 1963
Address: Not available
Title: Stereochemistry of Andrographolide
Source: Chem Indust 495
Notes: Not available
Author(s): Chander R, Srivastava V, Tandon JS, Kapoor NK
Year: 1995
Address: Division of Biochemistry, CDRI, Lucknow 266001
Title: Antihepatotoxic activity of diterpene of Andrographis paniculata (Kal-Megh) against
Plasmodium berghei induced hepatic change in Mastomys natalensis
Source: Int J Pharmacol 33: 135-138
Notes: Not available
Author(s): Chandra K, Pandey VN
Year: 1984
Address: Not "available"
Title: Some folk medicines of Singhbhum (Bihar)
Source: Sachtra Ayurved 37: 253-257
Notes: Not "available"
Author(s): Chang RS, Ding L, Chen GQ, Pan QC, Zhao ZL, Smith KM
Year: 1991
Address: Dept of Medical Microbiology, University of California, Davis 95616
Title: Dehydroandrographolide succinic acid monoester as an inihibitor against the human
immunodeficiency virus
Source: Proc Soc Exp Biol Med 197: 59-66
Notes: Dehydroandrographolide succinic monoester (DASM) is the dehydroandrographolyl ester
of succinic acid; and andrographolide, from which DASM is made, is the major
diterpenoid found in Andrographis paniculata. DASM has been found to be an inhibitor of
HIV in vitro. It was non toxic to H9 cell at the conc. of 50-200 micro gm/ml and was
inhibitory to the HIV-1(IIIB). It was inhibitory to two other strains of HIV-1 and a strain of
Author(s): Chang RS, Yeung HW
Year: 1988
Address: Not available
Title: Inhibition of growth of human immunodeficiency virus in vitro by crude extracts of Chinese
medicinal herbs
Source: Antiviral Research 9: 163-176
Notes: Reported anti_hiv activity of Andrographis paniculata
Author(s): Chaturvedi GN, Tomar GS, Tiwari SK, Singh KP
Year: 1983
Address: Not available
Title: Clinical studies on Kalmegh (Andrographis paniculata Nees) in infective hepatitis
Source: Ancient Science of Life 2: 208
Notes: Not available
Author(s): Chaudhuri SK
Year: 1978
Address: Not "available"
Title: Influence of Andrographis paniculata (Kalmegh) on bile flow and hexabarbitone sleeping
in experimental animals
Source: Ind J Exp Biol 16: 830-832
Notes: Not "available"
Author(s): Chauhan CK, Nanivadekar SA, Billimoria FR
Year: 1992
Address: Dept of pharmacology, LTM Medical College & Hospital, Sion, Bombay 400022
Title: Effect of a herbal hepatoprotective product on drug metabolism in patients of cirrhosis
and hepatic enzyme function in experimental liver damage
Source: Ind J of Pharmacology 24: 107-110
Notes: Whole plant of Kalmegha and fruits (without seed) of amalaki was powdered and 500 mg
tablets were prepared. The patients were given 4 tablets thrice daily for 30 days.
Wherever, treatments were given extended periods of up to 2-3 months. Results shows
that Andrographis paniculata (kalmegha) and Amalaki (Phyllanthus emblica) compound
is effective in viral hepatitis and can be used safely.
Author(s): Chen JH, Jiang RL
Year: 1980
Address: Not available
Title: Morphological and historical studies on Andrographis paniculata (Burm.f.) Nees and
comparison with four other Acanthaceae herbs.
Source: Yao Hsueh Pao 15: 750-760
Notes: Not available
Author(s): Chopra IC, Handa KL
Year: 1959
Address: Not "available"
Title: Role of Indegenous drugs in the practice of western medicine in India
Source: Pharmaceutist (Annual): 4(12)
Notes: Not "available"
Author(s): Choudhary BR, Poddar MK
Year: 1984
Address: Not available
Title: Not available
Source: IRCS Med sci 12: 466
Notes: Not available
Author(s): Dange SV, Shah KU, Bulakh PM, Joshi DR
Year: 1992
Address: Not "available"
Title: Efficacy of stimuliv, an indegenous compound formulation, against hepatotoxicity of
antitubercular drugs
Source: Ind J Chest Dis Allied Sci 34: 175-183
Notes: Not "available"
Author(s): Das A
Year: 1977
Address: Not "available"
Title: Action of Kalmegh: Is it enzyme induction?
Source: Ind Drugs 14: 167-168
Notes: Not "available"
Author(s): De S, Ravishankar B, Bhasar GC
Year: 1993
Address: Not available
Title: Plants with hepatoprotective activity - a review
Source: Ind Drugs 30: 355-363
Notes: Not available
Author(s): Deka L, Majumdar R, Dutta AM
Year: 1983
Address: Not "available"
Title: Some Ayurvedic important plants from district Kamrup (Assam)
Source: Ancient Sci Life 3: 108-115
Notes: Not "available"
Author(s): Deng WL
Year: 1985
Address: Not available
Title: Pharmacological studies on 13 kinds of injections from Andrographis paniculata. I.
Antipyretic, anti-inflammatory effects and toxicity.
Source: Chung Yao Tung Pao 10: 38-42
Notes: Not available
Author(s): Deng WL, Nei RJ, Liu JY
Year: 1982
Address: Not "available"
Title: Comparison of pharmacological effect of four andrographolides
Source: Chinese Pharmaceut Bull 17: 195-198
Notes: Not "available"
Author(s): Doreswamy R, Sharma D
Year: 1995
Address: Not available
Title: Plant drugs for liver disorders management
Source: Ind Drugs 32: 139-154
Notes: Not available
Author(s): Dutta A, Sukul NC
Year: 1982
Address: Dep Zool, Visva Bharti Univ, Santiniketan 731235, West Bengal, India
Title: Filariasis properties of a wild herb Andrographis paniculata
Source: J Helminthol 56: 81-84
Notes: compound herbal drug Tephroli, containing extracts of Tephrosia purpurea root, Eclipta
alba plant, Andrographis paniculata leaves and stems, Terminalia chebula ripe fruits and
Ocimum sanctum leaves and stems administered to the patients of viral hepatitis,
produced excellent results. It showed significant clearance of focal and general necrosis
and earlier subsidence of periportal inflammation.
Author(s): Dutta, Sukul
Year: 1983
Address: Not available
Title: Not available
Source: Nagarajan 27: 13-14
Notes: Not available
Author(s): Dwivedi RS, Singh KP
Year: 1977
Address: Not available
Title: Effect of foliar application of a urea and 2,4-D on the rhizospere microflora of
Andrographis paniculata Nees
Source: Proc of the National Academy of Sci (India) 47B: 145-152
Notes: Not available
Author(s): Dwivedi SK, Sharma NC, Mukherjee SC, Jawaharlal Panday NN
Year: 1987
Address: Indian Veterinary Research Institute, Izatanagar 243122
Title: Comparative efficacy of Liv 52 and Andrographis paniculata Nees in experimental liver
damage in rabbits
Source: Indian Drugs 25: 1-4
Notes: Pre-treatment and/or post-treatment of rats at different time intervals with different doses
of andrographolide in the two experimental models of hepatotoxicity showed that
treatment of rats with 400 mg/kg, ip, 1,4 and 7 h after paracetamol challenge leads to
complete normalization of toxin- induced increase in the levels of all the five biochemical
parameters, and significantly of all the five biochemical parameters and significantly
meliorates toxin- induced histopathological changes in the livers of experimental rats. the
results confirmed the in vivo hepatoprotective effect of andrographolide against
galactosamine or paracetamol induced hepatotoxicity in rats. Since the protective effect of
andrographolide was observed in two types of intoxication, which are very different in
their primary mechanism of inducing hepatotoxicity, it is suggested that protective
mechanisms of andrographolide which are not specific to galactosamine/paracetamol
toxicity may be responsible for the hepatoprotective activity of the compound.
Author(s): Erfan AM, Biswas KM, Chowdhury SA
Year: 1972
Address: Not available
Title: Not available
Source: Pakistan J Sci Ind Res 15: 53
Notes: Not available
Author(s): Feng PC et al
Year: 1962
Address: Not "available"
Title: Pharmacologic screening of some West Indian Medicinal plants
Source: J Pharm, London 14: 556-561
Notes: Not "available"
Author(s): Freer I, Fantoni GP, Picken DJ, Overton KH
Year: 1981
Address: Plant Tissue Culture Unit, Dept of Chemistry, University of Glasgow, Glasgow G12 8QQ
Title: Stereochemistry of the leucine 2,3-aminomutase from tissue cultures of Andrographis
paniculata
Source: J Chem Soc, Chem Commun, 80-82
Notes: A leucine 2,3-aminomutase from Andrographis tissue cultures mediates the equilibrium
between (2S)-alpha-and (3R)-beta- leucine; the activity does not apparently depend on
coenzyme B12.
Author(s): Fujita T, Fujitani R, Takedo Y, Takaishi Y, Yamada T, Kido M, Miura I
Year: 1984
Address: Not "available"
Title: Diterpenoids of Andrographis paniculata X-ray crystallographic analysis of
Andrographolide and structure determination of new minor diterpenoids
Source: Chem Pharm Bull 32: 2117-2125
Notes: Not "available"
Author(s): Fujita T, Fujitani R, Takedo Y, Takaishi Y, Yamada T, Kido M, Miura I
Year: 1984
Address: Not available
Title: X-ray crystallographic analysis of Andrographolide and structure determination of new
minor diterpenoids of Andrographis paniculata
Source: Chem Pharm Bull 32: 2117
Notes: Not available
Author(s): Gaind KN, Dar RN, Kaul RN
Year: 1963
Address: Dept of Pharmacy, Panjab University, Chandigarh-3, India
Title: Spectrophotometric estimation of andrographolide in Kalmegh
Source: The Ind J Pharmacy 25: 225-226
Notes: A spectrophotometric method of assay of andrographolide in Kalmegh by measuring its
absorption at 226 nanometer has been described. The method is found to be more rapid
and more accurate than the official method and other methods of assay so far reported.
Samples containing 0.02 mg or less of andrographolide content can be satisfactorily
estimated by this method.
Author(s): Garcia LL, Kintanar QL, Fojas FR, Sison FM, Chua NG, Villauneva BA
Year: 1980
Address: Not available
Title: Pharmacologic studies on the leaves of Andrographis paniculata Nees plant grown in
Philippines
Source: Acta Med Philipp 16: 59-68
Notes: Not available
Author(s): Girach RD, Aminuddin, Khan SA
Year: 1994
Address: Survey of Medicinal Plants Unit, Regional Research Institute of Unani Medicine, Bhadrak
Title: Andrographis paniculata - a possible substitute for Swertia chirata in southern India
Source: Int J Pharmacognosy 32: 95-97
Notes: This communication compares the ethnomedical uses of Andrographis paniculata in
southeastern India with reported uses of Swertia chirata. On the basis of similarities in
vernacular names and therapeutic actions, the former might be considered as a
substitute of the later.
Author(s): Goel AK, Mudgal V
Year: 1988
Address: Not available
Title: A survey of medicinal plants used by the tribals of Santal Pargana (Bihar).
Source: J Econ Tax Bot 12: 329-335
Notes: Not available
Author(s): Gorter MK
Year: 1911
Address: Not "available"
Title: The bitter constituent of Andrographis paniculata Nees
Source: Rec Trav Chim 30: 151-160
Notes: Not "available"
Author(s): Gorter MK
Year: 1914
Address: Not "available"
Title: Andrographolide
Source: Rec Trav Chim 33: 239-243
Notes: Not "available"
Author(s): Goswami BK, Vijayalakshmi K
Year: 1986
Address: Not available
Title: Nematicidal properties of some indegenous plant materials against root knot
nematodes, Meloidogyne incognita on tomato
Source: Indian J Nematol 16: 65-68
Notes: Not available
Author(s): Govindachari TR, Pai BR, Srinivasan M, Kalyana Raman PS
Year: 1969
Address: Not "available"
Title: Chemical investigation of Andrographis paniculata
Source: Ind J Chem 3: 306
Notes: Not "available"
Author(s): Govindarajan T, Subramanian D
Year: 1983
Address: Annmalai University, Annamalainagar 608002
Title: Karyological studies in South Indian Acanthaceae
Source: Cytologia 48: 491-504
Notes: The acanthaceae include 2200 species distributed among 240 genera with 4 centres of
distribution, namely, Indo-malaya, African, Brazil, and Central America northwars into
Mexico. An attempt is made in the present work to understand the cytotaxonomic
relationship of various species of acanthaceae.
Author(s): Guha Bakshi DN, Roy Choudhury KN
Year: 1972
Address: Not "available"
Title: Contribution to the Indian medicinal plants used in homeopathy
Source: Bull Bot Soc Beng 26: 25-29
Notes: Not "available"
Author(s): Guha Sircar SS, Moktwar A
Year: 1935-36
Address: Not "available"
Title: A crystalline brittle from Andrographis paniculata
Source: Sci & Cult I: 300
Notes: Not "available"
Author(s): Gupta et al
Year: 1994
Address: Not available
Title: Not available
Source: Appl Entomol Zool 29: 533-538
Notes: Not available
Author(s): Gupta KK, Taneja SC, Dhar KL, Atal CK
Year: 1983
Address: Not available
Title: Flavanoids of Andrographis paniculata
Source: Phytochemistry 22: 314-315
Notes: Not available
Author(s): Gupta S, Choudhry MA, Yadava JNS, Srivastava V, Tandon JS
Year: 1990
Address: Not available
Title: Anti-diarrhoel activity of diterpenes of Andrographis paniculata (Kal-Megh) against
Escheritia coli enterotoxin in in vivo models
Source: Int J of Crude Drug Res 28: 273-283
Notes: The plant Andrographis paniculata Nees (Acanthaceae) is widely used in traditional
remedies and folklore medicines in India for multiple clinical conditions. Recently two
diterpenes (andrographolide and neoandrographolide) isolated from this plant, have
been reported to possess promising immunostimulant activity. Therefore in the present
study we have evaluated the possible antiallergic activity of these diterpenes. they were
tested for anti-PCA (passive cutaneous anaphysixis) and mast cell stabilizing activities in
rats and compared with disodium cromoglycate (DSCG). Significant anti-PCA activity
(48-80%) was observed with andrographolides (25-100 mg/kg, p.o.) which was
comparable to that of DSCG (i.p.). Mast cell stabilizing activity (56-58%) was observed
against compound 48/80 induced degranulation. The results suggests that the
andrographolides possess promising anti-allergic activity with the added advantage of
Author(s): Gupta S, Yadava JNS, Tandon JS
Year: 1993
Address: Division of Microbiology, CDRI, Lucknow, India
Title: Antisecretory (anti-diarrhoel) activity of Indian medicinal plants against E. coli enterotoxin-
induced secretion in rabbit and guinea pig ileal loop models
Source: Int J Pharmacognosy 31: 198-204
Notes: Alcohol, hexane, chloroform, butanol and aqueous extracts of different parts of 31
indigenous medicinal plants of India were screened for their,# anti-secretory activity
against E. coli enterotoxin (LT, ST and LT/ST-induced secretory responses in rabbit and
guinea pig ileal loop models). The extracts of five plants- Andrographis paniculata,
Cassia fistula, Colens forskohlii, Tridax procumbens and Papaver somniferum showed
highly significant anti-secretory activity.
Author(s): Gupta V, Srivastava VK
Year: 1995
Address: National Bureau of Plant Genetic ReSource: s, Pusa Campus, New Delhi 110012
Title: Evaluation studies on Kalmegh (Andrographis paniculata Nees)
Source: Ind J Pl Genet ReSource: s 8: 141-143
Notes: Cultivation experiments, andrographolide extraction and quantification and evaluation
were described.
Author(s): Hancke J, Burgos R, Caceres D, Wikman G
Year: 1995
Address: Taubor Research, PO Box 86, Pirque, Chile
Title: A double-blind study with a new monodrug Kan Jang: decrease of symptoms and
improvement in the recovery from common colds
Source: Phytotherapy Research : 559-562
Notes: Reoprted clinical trials of a new monodrug Kan Jang made from Andrographis paniculata
against common cold
Author(s): Handa
Year: 1990
Address: Not available
Title: Not available
Source: Int J of Crude Drug Res 28: 273-283
Notes: Not available
Author(s): Handa
Year: 1991
Address: Not available
Title: Not available
Source: Ind Veterinary J 68: 314-316
Notes: Not available
Author(s): Handa SS
Year: 1990
Address: Dept of Pharmaceutical Sciences, Panjab University, Chandigarh 160016
Title: Hepatoprotective activity of andrographolide aginst galactosamine and paracetamol
intoxication in rats
Source: Ind J Med Res 92B: 284-292
Notes: Andrographis paniculata (Kalmegh) a plant used extensively in the Indian traditional
systems of medicine as a hepatoprotective and a hepatostimulative agent, was studied
in a four-day suppressive and against Plasmodium berghei NK65 in Mastomys
natalensis. A crude extract and fractionations reduced the level of parasitaemia in a dose
dependent manner; four diterpenes isolated from the n-butanol fraction, also suppressed
the parasitaemia level, but not in a dose dependent manner. Fifteen days of therapy with
neoandrographolide before infection suppressed parasite.
Author(s): Handa SS, Sharma A
Year: 1990
Address: Dept of Pharmaceutical Sciences, Panjab University, Chandigarh 160016
Title: Hepatoprotective activity of andrographolide from Andrographis paniculata against
carbontetrachloride
Source: Ind J Med Res 92B: 276-283
Notes: The alcoholic extract of Andrographis paniculata exhibited significant antidiarrhoel activity
against E. coli enterotoxins in animal models. The activity was further located in n-butanol
fraction which led to the isolation of four diterpenes, andrographolide,
neoandrographolide, deoxyandrographolide and andrographoside. Among these,
andrographolide and neoandrographolide showed similar activity to loperamide against
E. coli LT & LT/ST enterotoxins. Andrographolide was found to be superior against ST
enterotoxin, the most common cause of epidemics of neonatal diarrhea.
Author(s): Handa SS, Sharma A, Chakraborty KK
Year: 1986
Address: Not "available"
Title: Natural products and plants as live
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