"My love for you is like this scar: Ugly but permanent."- Grace to Will to help reassure him that she is not replacing him as her best friend (with Jack)
"Love ya like a cold sore!"- Karen to 'best friend' Helena Barnes
"Buy yourself some ugly."- Karen to Grace as she leaves a bargain store after failing her attempt to budget
"Charge yourself some happy."- Karen to Jack as she hands him a credit card to cheer him up after a 'break up'
"My boobies are fake and they're broken."-Grace to her date after her water bra sprung a few leaks
"That's not my soul you're looking at, buddy."- Karen to a guy that is talking to her while staring at her chest
"The lovelies were buzzing around me like...like what?" "Like moths to a flamer?"- WIll finishing Jack's sentence
"Grace honey, you're stuffed in a box getting rid of ass plaque. Face it, this party is a bust. Without Wilma you're nothing. I never was a big fan of Wills, but the girl can entertain."- Karen to Grace after Grace sits on a box at her apartment warming party without Will
"...all of Manhatten will be abuzz. Speaking of Manhatten and a buzz...."- Karen as she grabs a bottle of gin and a glass and heads for the bathroom
"Oh for Christ's Sake! It's just the four of us! Grab a bottle, hunker down, and pray for daylight!"- Karen to Grace's company at her apartment warming party
"Put down the cheese and return to the picnic area!"- Grace to Karen and the rest of her company as she directs them to a blanket like an air traffic controller
"Have you totally forgotten how to speak our language? 'I'm running late' is gay for 'I'm blowing you off'." "What's gay for goodbye?" "Good morning." "Good morning Jack." Jack and Will arguing because Will's date is late
"I just don't understand why anyone would subject themselves to a constant barrage of insults everyday." "Honey, your new dump smells like cat pee." "Never mind."- Grace to Will and Jack, interrupted by an insult from Karen
"Boy, they are like Siamese twins joined at their boring personalities."- Karen to Jack about Will and Grace
"Who jiffy-popped her head?"- Karen about Grace and her showercap
"Ooh, my very own sexless marriage, just like Will and Grace!"- Jack to Karen as they discuss his marrying Rosario so she can get a green card
"Hey poodle." "Who's your daddy?" "You are."- typical Karen and Jack greeting/exchange
"Karen! Are you flashing that woman?!" "She started it!" "Karen, she's breast feeding." "That would explain the ugly bald man."- Grace and Karen sitting in a restaurant lobby/bar
"Queen." "Hag."- Will's old teacher and his best friend (like an older Will and Grace)
