Cytadren usually comes in 250 mg
tablets in blister packs.It has been prescribed for many reasons. It was
originally used as a mild tranquilizer but then it was discovered that
it could be used to treat Cushings Syndrome as an anti-cortisone in the
body. Cushings Syndrome is a medical condition where the body overproduces
cortisol. Cortisone is a catabolic hormone which breaks down muscle in
the body. Cortisone prevents the protein synthesis in the muscle cell which
results in muscle breakdown. Most recently and really most commonly, it
has been used as an aromatize inhibitor to treat breast cancer in women.
This is really where this drug becomes interesting to bodybuilders. The
bodybuilders in the know don't use this drug as an anti-cortisol since
extremely low cortisol levels would not be of benefit. They primarily use
this drug as an aromatise inhibitor and to help in restoring HPTA function
after a steroid cycle. Low dose Cytadren use, in the area of no more than
250 mg/day selectively inhibits aromatise with minimal effect on the enzymes
that inhibit testicular and adrenal teroidogenesis. You would want to take
the 250 mg per day in divided doses. The referrable dosage schedule is
to divide the tablet into 4 equal parts and take 62.5 mg every 6 hours
or so. There are really three main reasons for taking it in low mg
divided doses like those that are listed.First off, you will be able to
keep the cytadren drug serum levels at a fairly constant moderate level
in the body throughout the day. This way it is more effective against aromatise
rather than just spiking it to a high level from taking an entire tab,
which also results in there being almost no desired anti-aromatise activity
for part of the day since the drug is largely eliminated from your body
due to the short half life being about 6-8 hours. The second main reason
for you wanting to keep the cytadren blood serum level low as opposed to
the high spike is that you will have a higher ratio of desired anti-aromatise
activity to undesired anti-desmolase activity. Cytadren works so well at
reducing cortisone production in the body that it makes your body produce
ACTH which stimulates corisone production as well effectively cancelling
out the effects of the drug.
Since I am recommending taking low frequent doses, you will be able
to keep from inhibiting desmolase activity thus avoiding the ACTH problems
that would be happening with the single dose spike. Whenever cortisol levels
are depressed by inhibition of desmolase, ACTH goes up in response. If
you get the drug out of your system while ACTH is still elevated cortisol
levels will rise to abnormally high levels for a time thus causing the
problems.The third main reason for keeping the dosage in the 250 mg per
day dosage is that it is low enough at that dosage to not inhibit testosterone
production by the body. Low dose cytadren selectively inhibits aromatise
with minimal effect on the enzymes that inhibit testicular and adrenal
steroidogenesis. Inhibition of aromatise can also result in increase in
LH because of reduced estrogen levels which would be beneficial in restoring
HPTA functioning post cycle. Most of the abstracts on Medline that
showed decreases in natural testosterone production were using closer to
1000 mg per day. Most people will be taking cytradren with steroids anyway
so this really could be considered a moot point. Side effects from this
drug are as follows: fatigue, dizziness, restlessness, depression, sleeping
problems, and headaches are the most common.
Package:
40 tablets per box. 250 mg per tablet.
Usage:
Average dose is 1 tablet a day.