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 OF THE FINAL CESSATION OF THE MENSES

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This chapter of the book opposite is the earliest medical description of menopause which I have found. The description is instantly recognizable and is little different to what is experienced today. Evidently little has changed in terms of "symptoms" over the last 163 years despite the fact that we are told that "'women didn't live to experience menopause till recently" ;-)

While it focuses on the all too familar problem of excessive bleeding, overall it has an upbeat attitude to the process and is at pains to debunk some of the phony horror stories which were already (and still are) in place.

I have appended a glossary of the remedies mentioned, and inserted synonyms enclosed in [] where the vocabulary is unusual. I have no idea if the preference for commas over periods is an idiosyncracy of the author or usual punctuation at the time.
 

The first indication of the approaching final cessation of the menses is often irregularity in the menses; and as this period is more frequently the one at which any latent disease of the uterus shows itself, it is always looked forward to with much anxiety by the female.(1) Indeed, so replete is this period with horrors to some, that we may very justly suspect it to be the cause of many of the distressing symptoms which sometimes accompany this interesting process of the human uterus.

Irregularity a frequent first clue -anxiety abounds

The reason of the discharge leaving the woman at this time of life, appears to be founded in Divine wisdom and beneficence; childbearing being thereby prevented beyond that  period at which the mother would be capable of extending her care to her offspring, in the ordinary probabilities of human life; and thus consequently submit her child to the doubtful management of strangers, or subject it to the waywardness and caprice of those who could not feel a parent's affection, or would not yield a mother's devotion to its many necessities and wants, at a period at which its helplessness would most require the kindest offices.

Menopause a function of God's wisdom and kindness

This change is sometimes so silently effected, that the woman scarcely takes notice of her altered condition; at others its approach is so gradual as not to attract observation, until the diminished quantity gives warning it is about to take its leave forever.

Some women are totally symptomless

For many ages opinions have been entertained that the final cause of this evacuation is an outlet for peccant humours [toxins], and hence the apprehensions of women probably arise; for wherever the discharge is less abundant than usual, the most serious fears are entertained lest its retention should excite disease, either in the uterus itself, or in some other part of the body; hence a diminished menstrous secretions always more alarming to the female, than an increased flow.

Reduced discharge causes apprehension

"The time of life," as it usually called, is without doubt an important epoch, and care and attention are then particularly called for, but the vulgar [commonplace] error, that  women at this period are always in danger, is not without mischief to the suffering sex; for it is doubtful whether they are necessarily more obnoxious [liable] to disease, at least to severe disease, at this than any other period of their existence. (2)That they are occasionally liable to disease at this time, and that disease one of the most terrible of human maladies, cannot be concealed, we mean cancer of the womb, but this disease is much more rare in the uterus than in certain other parts of the body, for example, the breasts; and perhaps we are within the proper limits when we say that there are three instances of the latter for one of the former.

Dangers much exaggerated.

If latent dispositions in the uterus and other parts to disease, become active about this period of life, it is not because the menses being about to cease excites them, but because the disease is slow in developing itself and is kept perhaps in check for a long time by the menstrual discharge serving as an important evacuation; especially when the uterus may be the seat of the complaint. In such a case the foundation of the disease is laid, or originated at a time when the menses were the most perfect, as regards period and quantity; consequently; they could have no agency in its production; but, on the contrary, from its frequently relieving the engorgement of the vessels, kept it in subjection for a long time. Coincidences in the human system are so common, that they are frequently mistaken for cause and effect, the cessation of the menses and the appearance of scirrhus [hard cancerous tumour] and cancer, or other maladies, being regarded as cause and effect.

Coincidence is not causal

Our present concern however, is with the derangement of the discharge at or about the period of cessation: this will consist in either diminution of the usual quantity, or an excess of it. With respect to the first, little need be said, as it is what is expected; but the excessive flow must be treated, for the most part, according to the rules prescribed for the management of hemorrhage from the uterus from any other cause; the indication being - to diminish the quantity discharging, and to prevent an excessive return.

Increased or decreased flow

To diminish the quantity of blood discharging:The first of these indications is best fulfilled by rest; cool air and drinks; cold local applications; by the use of acetate of lead and opium, no. 21; and by the plug. The patient so circumstanced must be immediately confined to a horizontal position, and every motion should be strictly forbidden; cool air must be admitted with freedom wherever practicable, and no nourishment nor drink be given, except they be cooled. Cold applications to the belly are frequently useful in excessive discharges of this kind; the best mode of applying them is by large bladders not quite filled with water in which there is ice, if it be in summer, or during hot weather: cold water alone will be sufficient if in winter. During the use of this, care should be taken to keep the feet and legs warm. We should also give one of the pills No. 21, and repeat it in an hour or less and continue it afterwards, if circumstances call for it. In urgent cases, the acetate of lead pills not being on hand, the ordinary mixture of sulphuric acid, alum and infusion of roses, may be taken or Ruspini's styptic. Should these means not control the discharge after a proper trial of them, recourse must be had to the plug, - a soft handkerchief may be folded, dipped in vinegar and water, and inserted quite up the passage.  The insertion of a small piece of ice in the first fold of the handkerchief, is attended with great advantage, and has often a powerful effect. The plug should never be allowed to remain longer than ten or twelve hours at a time, without being removed, cleansed and re-inserted.

Flooding and Treatment of heavy flow

The discharge of blood at this period of life is occasionally so great and so rapid as to threaten speedy exhaustion, and then it can be met only by the most prompt application of the most efficient remedies.  Whether this malady shews itself in the rapid expenditure of fluid blood, or in the repeated expulsion of large coagula [clots] it must be opposed by the same remedies - these two conditions present no difference of indication, nor any essential difference in the complaint itself; the former, however, generally requires more prompt interference than the latter as more blood is expended in a given time.

clots

To prevent an excessive return of this discharge. This second indication must be fulfilled by cautious blood-letting; purgative; alteratives; hemlock, and tonics. In those cases where there is an immense loss of blood at this period of life, there is an almost continual draining off of this fluid, after the violence of its issue is much abated; hence we sometimes find a greater or less discharge almost always present, which renders the woman not only very feeble, but keeps her mind in a state of extreme apprehension from one period to another. These two causes - the excessive discharge and mental anxiety, - keep the system in a constant state of excitement: and if the pulse be examined, it will frequently be found to be quick and tense. We are, therefore (unless the patient is constitutionally delicate and debilitated) under the frequent necessity of abstracting a few ounces of blood, especially towards that time which the disease has assumed for its movements - say in about every three or four weeks.

Treating flooding by bleeding the patient

To aid the vessels to contract, we should confine the patient to a strictly vegetable diet, or to a diet of milk, if this agree with her; all kinds of liquor and spices should be forbidden and exercise absolutely prohibited. The patient should sleep on a mattress, and should be directed to repose herself upon it, or a sofa, as often as she may feel a little weakened or fatigued by sitting up. The feet and legs should, however, be kept warm.

Treating flooding by diet and rest

It is great importance that the bowels should be kept freely open, by the regular exhibition of some mild purgative, as No. 5, 9 or 19. Aloes is generally considered to be bad medicine in these cases, but the hiera piera (it is a mixture of aloes and white canella bark) long the old woman's remedy, has certainly been serviceable. The following case may be given as worthy of some notice - A lady, aged forty-two years, for whom almost all the known remedies for this hemorrhage had been prescribed, with very little benefit, was told by some old woman that the hiera piera was a certain cure of her complaint; as this woman cited the cases of two or three ladies known to the patient, who had been benefited by it, and who, on application being made to them, strongly recommended it, she was allowed to make use of the old woman's prescription. This was half an ounce of hiera piera to a pint of gin, of which a wine-glassful was to be taken at bedtime: It was taken and the lady was completely intoxicated all night and very sick the next morning. Thinking the effects would next night be less severe, she again ventured it with similar result. She was now determined to abandon it, unless some less objectionable mode could be adopted for its exhibition - it was prescribed in the following manner:

Take of hiera piera, two drachms; oil of cloves, ten drops; castile soap, twelve grains; syrup of rhubarb, a sufficient quantity to form the mass - to be divided into forty pills.

One of these was directed every morning, noon and evening, unless they should prove too purgative; which did not occur, as the patient was of an extremely costive [prone to constipation] habit.  She soon perceived, after she began to use this medicine, a diminution of the discharge, and by the time she had finished the pills prescribed above, it was so much reduced in quantity, as to give no further uneasiness.  This and a few other cases of a similar kind, prove the importance of gentle purging in this condition

Purging necessary in cases of flooding

The extract of conium (hemlock) is often a useful medicine in this disorder, especially where the discharge is chiefly by coagula. It may be given in pills in the dose of three to six grains, or more, twice or thrice a day, and is serviceable in allaying irritability and relieving pain. I think the addition of  a small quantity of blue pill, and tartarized antimony (as in the form No.22) will often be more serviceable than the latter given alone, especially where there exists symptoms of great functional disorder in the liver and bowels

Use of hemlock for clots

When the condition of the patient is very much improved by these means, and debility remains, we may venture cautiously on a more generous diet, gentle exercise daily in the open air, and a little of the mildest kind of tonic, as infusion of cascarilla, gentian or calumba.

Convalescence

But what we have previously said refers only to the severe form of this complaint.; and we will now add a few words as to the management of the more ordinary cases. Commonly little or nothing is required beyond attention to keep the bowels open by means of beaume de vie, or one of the mild aperients No. 9 or 19, taken every or every other night, No. 22 or Plummer's pill; or the alterative pill No. 91 in the DOMESTIC MEDICINE, sometimes answers remarkably well. Together with these means, the exercises must be attended to and the diet should be nourishing, but rather less in quantity than usual.

"Ordinary" cases of increased flow need little attention

When a great many days are employed giving issue to a discharge, or, as the women term it, being almost constantly unwell, yet where the aggregate quantity may not greatly exceed the common monthly evacuation, some tonic and a mild alterative are indicated, also bathing the parts in cold water, abstaining from much exercise especially in the house, and from all stimulating food. Two drachms of rhatany, thrice a day in a wine-glassful of water, is very useful; or the infusion of cascarilla, as in No. 16, may be advantageously taken  In conjunction with these measures, a single pill of the acetate of lead, No. 21, or one pill taken now and then is likely to be of great service, particularly if the discharge appears disposed to increase in quantity.

Constant spotting

Many women at the period of the final cessation of the menses, although they do not suffer from a profuse discharge or hemorrhage, yet are much troubled with rheumatic or flying pains, head-ache, hot flushes and other troublesome symptoms. It is too common for such persons to go on along time unrelieved, and to be told that these feelings being necessarily produced by their state, there is little to be done but bear them patiently.  This, however, is a mistake, for I have found an alterative pill at night, similar to Plummer's pill, or No. 91 in the DOMESTIC MEDICINE, with sarsaparilla and rhubarb in the day, to be almost a sovereign remedy, provided the patient is careful of her diet, and attentive to her bowels and to exercise. In prescribing an alterative pill in these cases, we should vary the combination according to circumstances, sometimes giving half a grain of calomel, or less, in each pill, and sometimes adding a little Dover's powder, whereby its soothing effects are promoted. The kind of combination, and the doses, will of course make a great difference in the effects in different cases

Other symptoms warrant sympathy

Footnotes

1. Instances have occurred of the final cessation of this discharge so early as the thirty-fifth year, or even sooner, in our climate, and of their duration to the sixtieth year; but these are very uncommon. Dr. Dewees, of Philadelphia, has seen three instances where this evacuation has ceased altogether before the twenty-fifth year, and two others before the thirtieth year: the health of these women appeared to be as perfect as if they had this discharge in the most regular manner. back

2. The distinguished and experienced Denman used to say, "All women are alarmed at the time of the final cessation of the menses and are persuaded that the ill consequences which sometimes ensue, are to be prevented by proper care and management at this time. But it must be observed, that scarce one of a great number of women suffer more than temporary inconvenience on that account; and it is not reasonable to think that any disease should be a necessary consequence of the cessation of a discharge which is as perfectly natural as it's appearance or continuance."



M. Lisfranc, a Parisian practitioner of the present day, of considerable reputation, observes on this point, "We are not to believe, with most writers on this subject, that affectations of the uterus are more common at this period than at any other. The great law of physiology, that the more an organ is exercised, the more liable it is to morbid affections, here holds good as elsewhere. from thirty to thirty-five years of age, the reproductive organs are most exercised, and observation shews, that diseases are more common between those two periods. There are a great number of women affected with diseases of the uterus in the hospital at La Pitie, and amongst those so attacked I do not remark more than three who have reached the age of forty.-- Lectures on the Diseases of Women in The Lancet vol. i. 1833-34, p322 back

Glossary of remedy ingredients
Information largely from searches at http://my.webmd.com/  and at  http://www.ibiblio.org/herbmed/eclectic/kings/intro.html

Alterative: Any agent which "purifies the blood"
Blue Pill, contains gr. 1/3 of Mercury, with Liquorice, Althaea, Glycerin, and Honey of Rose. 

Althaea (marshmallow) used as an anti-infective, anti-inflammatory.
Liquorice used as a remedy for bronchitis, cough, stomach inflammation
Honey of Rose - rose extract added to honey. Slightly stimulant and astringent.

Calumba: Enfeebled stomach, with indigestion, or feeble digestion; anorexia, and general debility
Canella bark: useful in enfeebled conditions of the stomach and alimentary canal, and has been advised in scurvy, and in chlorotic, post partum, and carcinomatous menorrhagia.

Dover's powder: A powdered drug containing ipecac and opium,  to relieve pain and induce perspiration. 

Ipecac: an emetic
Opium: A narcotic, precursor of morphine

Gentian (root): a remedy for appetite loss and indigestion

Plummer's pills contain Sulphurated Antimony, Calomel, with Guaiac and Castor Oil. 

Antimony used as anti-infective agent but is potentially poisonous
Calomel: mercurous chloride. It is now classified as a hazardous product. Warning at http://www.jtbaker.com/msds/c0550.htm includes
Ingestion: Toxic! Average lethal dose for inorganic mercury salts is about 1 gram. May cause burning of the mouth and pharynx, abdominal pain, vomiting, bloody diarrhea. May be followed by a rapid and weak pulse, shallow breathing, paleness, exhaustion, tremors and collapse. Delayed death may occur from renal failure.
Guaiac also known as lignum vitae is a remedy for rheumatism.
Castor oil is a purgative.

Rhatany: an antinfective and astringent root used to treat hemorrhoids and wounds.
Sarsaparilla: Sarsaparilla has been used to treat urinary tract infections, psoriasis, and rheumatism, but there is no evidence that it relieves any of these problems.

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