Thyroid: Follicular adenoma

A well-circumscribed brownish fleshy mass was seen in surgical removal of the thyroid.  The rest of the gland was normal.

1.    Why is this section abnormal?  Describe the abnormal histological features.

Circumscribed nodule lying within normal thyroid tissue

Capsulated with a lot of follicles containing colloid, some colloid more eosinophilic than the rest

Follicles are of varying sizes

Benign looking acinar cells (normal nuclei)

2.    T/F.  The histological hallmark of this disease is:

      Inflammation F

      Hyperplasia F

      Neoplasia T

      None of the above F

The disease is supposed to be:

      Associated with SLE F

      Autoimmune with IgA against TRH receptor F

      Associated with somatic mutation related to cAMP cascade T

      None of the above F

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Copyright � Joseph Ong 2003