Analgesics, Anti-asthmatics, Endocrine Pharmacology, GIT Pharmacology

 

 

41.    Colchicine:

 

 

a.    F: binds to microtubules, inhibit mitosis and leucocyte migration.

b.    F: excreted in the bile.

c.    F

d.    T: rapidly relieves pain and inflammation, most effectively if it is used within 24h of onset of an acute attack.

 

 

42.    The following drugs may cause bone marrow depression:

 

a.     T

b.     T

c.     T

d.     T

 

 

43.    Effects of the local anaesthetics are influenced by:

 

a.     T

b.     T

c.     T

d.     T

 

 

44.    Lignocaine differs from procaine in that it has:

 

a.      T

b.      T

c.      T

d.      F

 

 

45.    Paracetamol:

 

a.      T

b.      T 

c.      F

d.      T

 

 

46.     Phenacetin:

 

a.      T

b.      T

c.      F

d.      F

 

 

47.    Caffeine:

 

a.      F

b.      T

c.      F

d.      T

 

 

48.    Plasma concentration of theophylline:

 

a.      T

b.      F

c.      T

d.      F

 

 

49.    Allopurinol potentiates:

 

a.      F

b.      T

c.      T

d.      F

 

 

50.    Sulindac as the sulfoxide:

 

 

a.      T: less adverse effects in kidney due to selective inhibition of only extra-renal COX.

b.      T: is converted to active sulphide metabolide in the body and by gut flora.

c.      F

d.      T

 

 

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