Pharmacology of the Cardiovascular and Central Nervous Systems

131.    The following statements are true:

a.     phenytoin can induce its own metabolism.

b.     primidone is metabolized to phenobarbitone.

c.     sodium valproate is effective in all forms of epilepsy.

d.     phenytoin can cause gum hyperplasia and acne.

e.     ethosuximide is used in the treatment of petit mal epilepsy.

132.    The following are used in the treatment of grand mal epilepsy.

a.     phenytoin.

b.     phenobarbitone.

c.     nikethamide.

d.     diazepam.

e.     primidone.

133.    The following drugs can cause convulsions:

a.     doxapram.

b.     strychnine.

c.     tricyclic antidepressants.

d.     methohexitone.

e.     picrotoxin.

134.   Blockade of muscarinic receptors in the CNS:

a.      by hyoscine leads to agitation and excitement.

b.      causes nausea and vomiting.

c.      by hyoscine can impair short-term memory.

d.      by atropine may be reversed by physostigmine.

e.      by benztropine can decrease tremor in Parkinson's disease.

135.    Morphine:

a.      mimics the actions of enkephalins.

b.      does not cause dependence.

c.      can cause constipation.

d.      acts as a partial agonist.

e.      is only administered orally.

136.    Beta-endorphin is:

a.      a peptide.

b.      a neurotransmitter.

c.      present in the pituitary.

d.      an opiate-receptor antagonist.

e.      an analgesic.

137.    H1-receptor blockers:

a.      have an arousing action in the CNS.

b.      are used as anti-emetics.

c.      include chlorpromazine.

d.      may have muscarinic receptor-blocking actions.

e.      prevent histamine-induced gastric secretion.

138.    Codeine:

a.      occurs in opium.

b.      frequently causes diarrhoea.

c.      is used to treat nausea caused by morphine.

d.      is equipotent to morphine.

e.      depresses the cough reflex.

139.    Indicate whether the following statements are correct:

a.      naloxone will precipitate withdrawal symptoms in a morphine addict.

b.      naloxone is a useful in treating barbiturate-induced respiratory depression.

c.      pethidine is a useful cough suppressant.

d.      pethidine constricts the pupil.

e.      naloprine is a partial agonist.

140.    The following statements are true:

a.      tolerance to, and dependence on, ethanol do not occur.

b.      methanol is more rapidly metabolized than ethanol.

c.      ethanol can be given to reduce the toxic actions of methanol.

d.      ethanol is a clinically used diuretic.

e.      ethanol metabolism is accelerated by disulfiram.

<< Last Page                       Answers                             Next Page >>