Pharmacology of the Cardiovascular and Central Nervous Systems
131. The following statements are true:
a. T
b. T
c. T
d. T
e. T
132. The following are used in the treatment of grand mal epilepsy.
a. T
b. T
c. F: it is a general CNS stimulant and can cause convulsions.
d. F
e. T
133. The following drugs can cause convulsions:
a. T: it is used as a respiratory stimulant.
b. T: it is a blocker a glycine receptors in the spinal cord.
c. T
d. T
e. T: it is an antagonist at GABA-A receptors in the spinal cord.
134. Blockade of muscarinic receptors in the CNS:
a. F: hyoscine tends to cause sedation; atropine, however, does cause agitation and excitement.
b. F: hyoscine is used to prevent travel sickness.
c. T: cholinergic mechanisms appear to be vital for short-term memory.
d. T: physostigmine, an inhibitor of acetylcholinesterase, enters the CNS.
e. T
135. Morphine:
a. T
b. F
c. T
d. F
e. F
136. Beta-endorphin is:
a. T: beta-endorphine is an endogenous opioid peptide derived from beta-lipotropin, a fat-mobilizing hormone of the pituitary.
b. T: it is the most potent endogenous agonist at mu-opiate receptors.
c. T
d. F
e. T
137. H1-receptor blockers:
a. F: generally cause drowsiness and sedation, and can cause sleep.
b. T
c. T: chlorpromazine blocks histamine H1, muscarinic, dopamine and alpha-adrenergic receptors.
d. T
e. F
138. Codeine:
a. T
b. F
c. F
d. F: codeine has 1/10 the potency of morphine.
e. T
139. Indicate whether the following statements are correct:
a. T
b. F
c. F
d. F: pethidine has some atropine-like activity and in overdose in likely to dilate the pupil
e. T: it stimulates the opiate receptors before blocking them.
140. The following statements are true:
a. F
b. F
c. T
d. F
e. F