Pharmacokinetics, Pharmacodynamics, Pharmacology of Autonomic nervous system drugs, Autocoids

 

 

41.    The following drugs combine with the biological components indicated:

a.    T

b.    T

c.    F

d.    T

 

 

42.    Prostacyclin:

 

a.     F

b.     T

c.     T

d.     T

 

 

43.    Prostaglandins have a wide range of actions which include:

 

a.     T

b.     T

c.     F: stimulates uterus contraction initiating labor.

d.     T

 

 

44.    Parasympathetic blockade is enhanced by:

 

a.      F

b.      F

c.      T

d.      F

 

 

45.    If a drug undergoes significant first-pass effect, it means that:

 

a.      F 

b.      F 

c.      F

d.      F

 

 

46.    The following statements refer to the microsomal mixed function oxidase system:

 

a.      F: acts on a wide variety of substances; non-specific.

b.      F: the dosage will have to be increased due to increased drug metabolism.

c.      T

d.      T

 

 

47.    Neostigmine:

 

a.      T: it is a quarternary amine and hence poorly soluble.

b.      T: forms a carbamyl ester linkage with acetylcholinerase which undergoes slow hydrolysis.

c.      T

d.      T

 

 

48.    Propranolol is used the treatment of:

 

a.      T

b.      F

c.      T 

d.      F

 

 

49.    Noradrenaline at adrenergic nerve endings:

 

a.      T 

b.      F

c.      F

d.      T

 

 

50.    Adrenaline:

 

a.      T

b.      F

c.      F

d.      F: noradrenaline is the neurotransmitter.

 

 

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