Pharmacokinetics, Pharmacodynamics, Pharmacology of Autonomic nervous system drugs, Autocoids
21. If the elimination of a drug follows first order kinetics it indicates:
a. F
b. F
c. T
d. F
22. Binding of a drug to plasma proteins:
a. F: basic drugs like lignocaine binds to alpha1-glycoproteins in the plasma.
b. F
c. F
d. F: Vd will be lower as less of the drug will be distributed to the tissue.
23. Anaphylactic responses to a drug:
a. T
b. F
c. F
d. F
24. The following are antihistamines which act on H1 receptors:
a. F: acts on H2 receptors to decrease gastric acid secretion.
b. T
c. F: is an NSAID.
d. T
25. Diphenhydramine:
a. T
b. T
c. T
d. F
26. Antihistamines should not be used indiscriminately as they are likely to cause:
a. T
b. T
c. T
d. F
27. State true or false:
a. T
b. T
c. F: potency is a measure of the drug dosage needed to produce a desired therapeutic effect.
d. T
28. Statement below refers to the distribution of drugs in the body.
a. F: only lipid-soluble drugs are able to pass through cell membranes and enter the tissues.
b. F: it is freely permeable to lipophilic drugs.
c. F
d. F: the rate of dissociation is equal to rate of binding.
29. The following characteristics refer to the renal clearance of drugs:
a. F: excretion is enhanced by acidifying the urine.
b. T
c. F
d. F
30. The time taken to reach steady state concentration when the drug is administered orally is determined by:
a. F
b. T: time taken to reach Css = 5 x T1/2.
c. F
d. F