Structure & Property

Transmission

Clinical findings

Laboratory diagnosis

Treatment

Family: picorna

Genome: single-strand RNA, positive polarity.

Size: 20-30nm

Icosahedral nucleocapsid

Nonenveloped

More than 30 serotypes isolated.

Transmitted by fecal-oral route.

Aseptic meningitis (leading cause together with mumps & coxsackieviruses)

Upper respiratory tract infections

Febrile illness with or without rash.

Infantile diarrhea.

Hemorrhagic conjunctivitis

Isolation:

- feces

- throat swabs

Diagnosis made by isolation of virus in cell culture.

Serologic tests are of little value.

No antiviral therapy or vaccine available.