Who am I?
Home Who am I? Projects Others

 

 

Curriculum Vitae

 

 

 Personal Information

 

Name:    

 

Date of birth: 

Place of birth:

Nationality: 

 

Postal Address: 

 

 

 

 

 

 

E-mail: 

URL:

 João Miguel Carrapa Nunes Dias

 

20 December 1970

Lisboa

Portuguese

 

Serono Pharmaceutical Research Institute

Serono

Geneva

Switzerland

 

 

 

jmcndias at yahoo.com

http://www.geocities.com/jmcndias

 

 

 

 

Abstract

Protein Crystallographer (11 years experience, MAD, MIR, MR, Cryo). Industry experience (3 years), post-doc at Serono   Pharmaceutical Research Institute (SPRI, Geneva) since the end of 2003. Previous post-doc at Faculdade Ciências Tecnologia (FCT-UNL). Ph.D. in Structural Biology at FCT-UNL and Max-Planck Institut Biochemie (MPIB, Munich, Germany). Chemistry teacher of the pre-universitary course “International Baccalaureate”. Teacher of Chemistry Laboratory Techniques at Colégio Planalto, Lisbon. Graduation in Biochemistry at Faculdade Ciências Lisboa (FCL).  

 

Selected Achievements

Industry - Solved the structure of a novel secreted protein by MIR methods, up to 1.60Å. Solved the structure of the glycosylated version of this protein, up to 2.70 Å. Solved the structure of the complex (1.90Å) between this protein and a human relevant protein, by MR methods using the previously solved MIR structure. Interested in Structure-Based Drug Design, fragment based drug discovery to support "Hits to Leads" programs.

 

Career- 12 PDB deposited structures (involvement in the project):

2NAP - periplasmic nitrate reductase from Desulfovibrio. (D.) desulfuricans (Ph.D.,MAD)

1Z1N - hexaheme cytochrome c from D. desulfuricans (MAD)

1RZ5 -  activated di-haem cytochrome c peroxidase from Pseudomonas nautica (Ph.D., MR)

1RZ6/1NML - inactive di-haem cytochrome c peroxidase from Pseudomonas nautica (Ph.D., MR)

1OAH - cytochrome c nitrite reductase from D. desulfuricans (crystallization, MAD)

1H0H - tungsten containing formate dehydrogenase from D. gigas (MR, MAD)

1VLB - aldehyde oxidoreductase from D. gigas (High resolution)

1DGJ - aldehyde oxidoreductase from D. desulfuricans (MR)

1SFP - bovine acidic seminal fluid protein (crystallization, MIR)

1CTJ - cytochrome c6 from Monoraphidium braunii (crystallization)

1GVZ - prostate specific antigen from stallion seminal plasma (crystallization)

 

 

Professional experience

I have performed “de novo” protein structure determination and supported the “Hits to Leads” kinases program, including fragment-based drug discovery. I have a thorough knowledge of protein crystallography, with experimental hands-on molecular biology, protein expression (E. coli), Se-Met labeling (E. coli), protein purification (E. coli, Baculo virus/Insect cells, mammalian systems CHO and HEK), protein deglycosylation, co-crystallization, protein crystallography (MAD, MIR, MR) and cryotechniques. I have participated in the automatization of Serono´s crystallographic platform by implementing a nanodrop crystallization system (Mosquito) and being responsible for a crystal growth monitorization system (Crystal Farm). I also have extensive experience in synchrotron data collection at the Swiss Light Source (SLS, Villigen, Switzerland), ESRF (Grenoble, France) and DESY-HASYLAB (Hamburg, Germany).

 

Since 2003 Post-doctoral fellowship at Serono Pharmaceutical Research Institute (Serono, Geneva), in the CADD (Computer Assisted Drug Design) group under the supervision of Dr. J.P. Shaw.

Responsibilities

-“de novo” structure determination of secreted proteins from the functional genomics pipeline.

- Support of the “Hits to Leads” kinase program through fragment-based drug design.

- Responsible for the efficient functioning of the Crystal Farm, and maintenance of various crystallographic software packages.

Achievements

-Solved the structure of a complex (1.90Å) between a chemokine binding protein with a human chemokine, by MR methods using the previously solved MIR structure (manuscript in preparation).

-Designed mutants of both the chemokine-binding protein and various chemokines in order to explore the structure-function relation of the two complex partners.

-Solved the structure of a novel chemokine binding protein, by MIR methods, up to 1.60Å.

-Solved the glycosylated version of the same chemokine binding protein, up to 2.70 Å.

-Solved the structure of a human chemokine, by MR methods, up to 1.75Å.

-Initial fragments bound to the active site were found by crystallographic studies, and will be considered by the chemistry “Hits to Leads” kinase program.

 

2002-2003 Post-doctoral fellowship at Departamento de Química, Centro de Química Fina e Biotecnologia, Faculdade de Ciências e Tecnologia - Universidade Nova de Lisboa (FCT-UNL).

Responsibilities

-Leaded the group X-ray diffraction data collection at Synchrotron Source Radiation Laboratories: ESRF (Grenoble, France) and DESY-HASYLAB (Hamburg, Germany). Also responsible for the supervision of Ph.D. students and laboratory technicians.

Achievements

-Published the results in peer-reviewed journals, and presented in scientific conferences. Several crystal structures were deposited in the PDB as a result of an efficient use of the available synchrotron beam-time (approximately 12 days per year).

 

1997-2002 Ph. D. in Structural Biochemistry: "Structure and Function of Nitrate Reductase and of di-haem Cytochrome c Peroxidase", by Universidade Nova de Lisboa, under the orientation of Prof. Maria João Romão (Protein Crystallography, Dep. Química, FCT-UNL) and Prof. Robert Huber (Max Planck Institut für Biochemie, Abteilung für Strukturforschung, Martinsried, Germany), Ph.D. grant (PRAXIS XXI/BD/13530/97).

 

1995-1997  Trainee with a PRAXIS XXI Scientific Researcher Fellowship (BIC, JNICT).  "Structural characterisation of molybdenum and tungsten containing enzymes", at Instituto de Tecnologia Química e Biológica (ITQB), Oeiras, Portugal.

 

1993-1997 International Baccalaureate Chemistry teacher and Chemistry Laboratory Techniques  (years 10, 11 and 12 of the portuguese curricula), at Colégio Planalto.

Responsibilities

-Teaching Chemistry and preparing the students for the world exams.

-Installation of the Chemistry Laboratory.

Achievements

-Successful implementation of the Chemistry lectures of the International Baccalaureate at Colégio Planalto.

-Installation of the laboratory of Chemistry according to the International Baccalaureate requirements.

-All students successfully continued their education in University.

 

1992-1993 Trainee with a Young Researcher Fellowship (BJI, JNICT). "Crystallographic studies of proteins involved in electron transfer processes", at  ITQB.

1988-1993 Graduation in Biochemistry, Faculdade Ciências de Lisboa, Universidade Clássica Lisboa.

 

Teaching experience

October 2001 -  “Determinação de Estruturas Moleculares por Difracção de Raios-X”, Cursos Monográficos 2001, Dep. Química, CQFB, FCT-UNL, Caparica, Portugal.

November 2000 - "Determinação de Estruturas Moleculares por Difracção de Raios-X", Cursos Monográficos 2000, Dep. Química, CQFB, FCT-UNL, Caparica, Portugal.

January 1998 - “Análise Estrutural de Proteínas: um curso práctico”, IST, Lisboa, Portugal.

October 1993 -  May 1997    International Baccalaureate Chemistry teacher and Chemistry Laboratory Techniques  (years 10, 11 and 12 of the portuguese curricula), at Colégio Planalto.

 

Scientific Interests

Main scientific area of research

Protein Crystallography and Functional Genomics.

Structural characterization of human proteins with potential therapeutic applications.

Other scientific areas of interest

Structure and Function Relationship, Protein Crystallography, Biochemistry, Molecular Biology, Drug-design, Human genome.

 

Computer Sciences knowledge:

I have mastered a large number of crystallographic software packages (Linux, Unix) such as: HKL 2000 (Xdisp, Denzo, Scalepack), CCP4, Mosfilm, Refmac, SOLVE/RESOLVE, SHARP, ARP/WARP, CNS/CNX (XPLOR), SHELX, COOT, O, Turbo-Frodo, Uppsala package, Grasp, Pymol, Molscript, Raster3D, etc…


Publications (20)

20 – João M. Dias, T. Alves, C. Bonifácio, A. S. Pereira, J. Trincão, D. Bourgeois,  I. Moura & M.J. Romão (2004): "Structural basis for the mechanism of Ca2+ activation of the di-heme cytochrome c peroxidase from Pseudomonas nautica 617.", Structure, 12 (6) 961-973. (reprint).

19 – T. Santos-Silva, João M. Dias, G. Bourenkov, H. Bartunik, I. Moura & M.J. Romão (2004): "Crystallization and preliminary X-ray diffraction analysis of the 1-haem cytochrome of Desulfovibrio gigas", Acta Cryst, D60, 968-970. (reprint)

18 – C.A. Cunha, S. Macieira, João M. Dias, G. Almeida, L.L. Gonçalves, C. Costa, J. Lampreia, R. Huber, J.J. Moura, I. Moura & M.J. Romão (2003): "Cytochrome c nitrite reductase from Desulfovibrio desulfuricans ATCC 27774. The relevance of the two calcium sites in the structure of the catalytic subunit (NrfA).", J. Biol. Chem., 278 (19), 17455-17465. (reprint)

17 – C. Bonifácio, C.Cunha, A. Müller, C. Timóteo, João M. Dias, I. Moura & M.J. Romão (2003): "Crystallization and preliminary X-ray diffraction analysis of the di-haem cytochrome c peroxidase from Pseudomonas stutzeri", Acta Cryst, D59, 345-347. (reprint)

16 – H. Raaijmakers, S. Macieira, João M. Dias, S. Teixeira, S. Bursakov, R. Huber, J.J.G. Moura, I. Moura & M.J. Romão (2002): "Gene sequence and the 1.8 Å crystal structure of the tungsten-containing formate dehydrogenase from Desulfovibrio gigas", Structure Fold Des, 10 (9), 1261-1272. (reprint)

15 – João M. Dias, C. Bonifácio, T. Alves, J.J.G. Moura, I. Moura & M.J. Romão (2002): "Crystallization and preliminary X-ray analysis of two pH-dependent forms of a di-haem cytochrome c peroxidase from Pseudomonas nautica", Acta Cryst, D58, 697-699. (reprint)

14 – J. Rebelo, João M. Dias, R. Huber, J.J.G. Moura & M.J. Romão (2001): "Structure refinement of the aldehyde oxidoreductase from Desulfovibrio gigas (MOP) at 1.28 Å", J Biol Inorg Chem, 6, 791-800. (reprint)

13 - A.L. Carvalho, João M. Dias, L. Sanz, A. Romero, J.J. Calvete & M.J. Romão (2001): "Purification, crystallization and identification by X-ray analysis of a prostate kallikrein from horse seminal plasma", Acta Cryst, D57, 1180-1183. (reprint)

12 - M.J. Romão, João M. Dias & I. Moura (2001): "Dissimilatory Nitrate Reductase", in A. Messerschmidt, R. Huber, T. Poulos & K. Wieghardt (eds), Handbook of Metalloproteins, JohnWiley and Sons, Chichester, England, 1075-1085. (reprint)

11 – H. Raaijmakers, João M. Dias, R. Huber, J.J.G. Moura, I. Moura & M.J. Romão (2001): "Tungsten-containing formate dehydrogenase from Desulfovibrio gigas: metal identification and preliminary structural data by multi-wavelength crystallography", J Biol Inorg Chem, 6, 398-404. (reprint)

10 – R. Kiefersauer, M.E. Than, H. Dobbek, L. Gremer, M. Melero, S. Strobl, João M. Dias, T. Soulimane & R. Huber (2000): "A novel free-mounting system for protein crystals: Transformation and improvement of difraction power by accurately controlled humidity changes", J Applied Cryst, 33, 1223-1230. (reprint)

9 – J. Rebelo, S. Macieira, João M. Dias, R. Huber, C. Ascenso, F. Rusnak, J.J.G. Moura, I. Moura & M.J. Romão (2000): "Gene sequence and Crystal Structure of the Aldehyde Oxidoreductase from Desulfovibrio desulfuricans ATCC 27774", J Mol Biol, 297, 135-146. (reprint)

8 – R.O. Duarte, M. Archer, João M. Dias, S. Bursakov, R. Huber, I. Moura, M.J. Romão & J.J.G. Moura (2000): "Biochemical/Spectroscopic Characterization and Preliminary X-Ray Analysis of a New Aldehyde Oxido-Reductase isolated from Desulfovibrio desulfuricans ATCC 27774", Biochem Biophys Res Commun, 268, 745-749. (reprint)

7 - João M. Dias, C.A. Cunha, S. Teixeira, G. Almeida, C. Costa, J. Lampreia, J.J.G. Moura, I. Moura & M.J. Romão (2000): "Crystallization and preliminary X-ray analysis of a membrane-bound nitrite reductase from Desulfovibrio desulfuricans ATCC 27774", Acta Cryst, D56, 215-217. (reprint)

6 - João M. Dias, M. Than, A. Humm, R. Huber, G. Bourenkov, H. Bartunik, S. Bursakov, J. Calvete, J. Caldeira, C. Carneiro, J.J.G. Moura, I. Moura & M.J. Romão (1999): "Crystal structure of the first dissimilatory nitrate reductase at 1.9 Å solved by MAD methods", Structure Fold Des, 7(1), 65-79. (reprint)

5 - João M. Dias, S. Bursakov, C. Carneiro, J. Moura, I. Moura & M. J. Romão (1999): "Crystallization and preliminary X-ray analysis of a nitrate reductase from Desulfovibrio desulfuricans ATCC 27774", Acta Cryst, D55, 877-879. (reprint)

4 - Maria J. Romão, Ingo Kölln, João M. Dias, Ana L. Carvalho, Antonio Romero, Paloma F. Varela, Líbia Sanz, Edda Töpfer-Petersen & Juan J. Calvete (1997): "Crystal Structure of acidic seminal fluid protein (aSFP) at 1.9 Å resolution: a bovine polypeptide of the spermadhesin family", J Mol Biol, 274, 650-660. (reprint)

3 - Antonio Romero, Maria J. Romão, Paloma F. Varela, Ingo Kölln, João M. Dias, Ana L. Carvalho, Libia Sanz, Edda Töpfer-Petersen & Juan J. Calvete (1997): "The crystal structures of two spermadhesins family, reveal the CUB domain fold", Nature Structural Biology, 4(10), 783-788. (reprint)

2 - João M. Dias, Ana L. Carvalho, Ingo Kölln, Juan J. Calvete, Edda Töpfer Petersen, Paloma F. Varela, Antonio Romero, Claus Urbanke & Maria J. Romão (1997): "Crystallization and preliminary X-ray diffraction studies of aSFP, a bovine seminal plasma protein with a single CUB domain architecture", Protein Science, 6, 725-727. (reprint)

1 - Carlos Frazão, João M. Dias, Pedro M. Matias, Maria J. Romão, Maria A. Carrondo, Manuel Hervás, José A. Navarro, Miguel A. De la Rosa & George Sheldrick (1995): "Cytochrome c6 from the green alga Monoraphidium braunii. Crystallization and preliminary diffraction studies", Acta Cryst, D51, 232-234. (reprint)

 

Oral Presentations (20)

20 - João M. Dias (2006): “Embracing Chemokines: Understanding Specificity and Selectivity of Chemokine Binding Proteins”, 6th Conference “Structure-Based Drug Design”, 15-16 June 2006, CHI, Boston, USA.

19 - João M. Dias (2004): "Protein Crystallography and the Functional Genomics Pipeline", Chemistry Department, SPRI, 25 August, Geneva, Switzerland.

18 - João M. Dias (2003): "CCP", SPRI, Serono, September, Geneva, Switzerland.

17 - João M. Dias (2003): "CCP - Alvo em movimento: alterações conformacionais promovidas pela activação da peroxidase di-hémica do citocromo c", CQFB, September, Monte de Caparica, Portugal.

16 - João M. Dias (2003): "CCP", Glaxo Wellcome Medicines Research Centre, GSK, August, Stevenage, England.

15 - João M. Dias (2002): "Ritmos Cristalinos: peroxidases em movimento", XVI Ciclo de Conferências do Departamento de Química, CQFB, 18 December, Monte de Caparica, Portugal.

14 - João M. Dias (2002): "Structure and Function of Nitrate Reductase and of di-haem Cytochrome c Peroxidase", Ph.D. thesis, Faculdade Ciências e Tecnologia, Universidade Nova de Lisboa, 25 June, Monte de Caparica, Portugal.

13 - João M. Dias, C. Bonifácio, T. Alves, D. Bourgeois, J.J.G. Moura, I. Moura & M.J. Romão (2001): "Crystal structure of two pH-dependent forms of a di-haem cytochrome c peroxidase from Pseudomonas nautica", 2nd Meeting RequiMte, CQFB-CEQUP, 28-29 September, Monte de Caparica, Portugal.

12 -João M. Dias, C. Bonifácio, T. Alves, D. Bourgeois, J. J.G. Moura, I. Moura & M. J. Romão (2001): "Crystal structure of two pH-dependent forms of a di-haem cytochrome c peroxidase from Pseudomonas nautica", 27th Fed. Eur. Biochemical Society Meeting, FEBS-PABMB-SPB, 30 June-5 July, Lisbon, Portugal.

11 - João M. Dias, C. Bonifácio, T. Alves, D. Bourgeois, J. J.G. Moura, I. Moura and M. J. Romão (2001): "Crystal structure of two pH-dependent forms of a di-haem cytochrome c peroxidase from Pseudomonas nautica", COST Action D21- Metalloenzymes and Chemical Biomimetics, 31 March-1 April, Monte de Caparica, Portugal.

10 - João M. Dias, C. Bonifácio, T. Alves, D. Bourgeois, J. J.G. Moura, I. Moura and M. J. Romão (2001): "Crystal structure of two pH-dependent forms of a di-haem cytochrome c peroxidase from Pseudomonas nautica ", Dep. Química, FCT-UNL, 23 February, Monte de Caparica, Portugal.

9 - Hans Raaijmakers, S. Teixeira, João M. Dias, A. L. Carvalho, S. Bursakov, M.J. Almendra, I. Moura, J.G. Moura and M. J. Romão (2000): "D. gigas Formate dehydrogenase: Use of tungsten anomalous scattering to solve a 2x (88+29) kDa protein", Chemical Prospectives in Crystallography of Molecular Biology, 31st Course of International School of Crystallography, 25 May – 4 June, Erice, Italy.

8 - João M. Dias, M. Than, R. Huber, G. Bourenkov, H. Bartunik, S. Bursakov, J. J.G. Moura, I. Moura and M. J. Romão (1999): "Crystallographic studies of a dissimilatory nitrate reductase and mechanistic implications", 5th European Workshop on Crystallography of Biological Macromolecules, 16-20 May, Como, Italy.

7 - João M. Dias, M. Than, A. Humm, R. Huber, G. Bourenkov, H. Bartunik, S. Bursakov, J. Caldeira, C. Carneiro, J. J.G. Moura, I. Moura and M. J. Romão (1999): "The first crystal structure of a dissimilatory nitrate reductase", 1st Meeting RequiMte, CQFB-CEQUP, 5-6 February, Porto, Portugal.

6 - João M. Dias, M. Than, A. Humm, R. Huber, G. Bourenkov, H. Bartunik, S. Bursakov, J. Calvete, J. Caldeira, C. Carneiro, J. J.G. Moura, I. Moura and M. J. Romão (1998): "The first crystal structure of a dissimilatory nitrate reductase solved by MAD methods", 2nd Portuguese Spanish Biophysics Congress, VI Congreso Sociedad Biofisica España, 4-7 December, Madrid, Spain.

5 - João M. Dias, M. Than, A. Humm, R. Huber, G. Bourenkov, H. Bartunik, S. Bursakov, J. Calvete, J. Caldeira, C. Carneiro, J. J.G. Moura, I. Moura and M. J. Romão (1998): "The first crystal structure of a dissimilatory nitrate reductase solved by MAD methods", Dep. Química, FCT-UNL, 27 November, Monte de Caparica, Portugal.

4 - João M. Dias, M. Than, A. Humm, R. Huber, G. Bourenkov, H. Bartunik, S. Bursakov, J. Calvete, J. Caldeira, C. Carneiro, J. J.G. Moura, I. Moura & M. J. Romão (1998): "Crystal Structure of the first Dissimilatory Nitrate Reductase (NAP) at 1.9 Å solved by MAD", Structure and Function of Metalloproteins, ISTAS, ITQB, 7-19 September, Oeiras, Portugal.

3 - João M. Dias, M. Than, A. Humm, R. Huber, G. Bourenkov, H. Bartunik, S. Bursakov, J. Calvete, J. Caldeira, C. Carneiro, J. J.G. Moura, I. Moura and M. J. Romão (1998): "Crystal Structure of a Periplasmic Nitrate Reductase (NAP) from Desulfovibrio desulfuricans ATCC 27774 solved by MAD Methods", Spectroscopy and Engineering of Metalloproteins, ISTAS, ITQB, 6-19 July, Oeiras, Portugal.

2 - João M. Dias, Margarida Archer (1998): "Análise da Estrutura, Limitações do Modelo e Critérios de Fiabililidade de um Modelo Cristalográfico (PROCHECK, OOPS e DALI) - Análise Estrutural de Proteínas: um curso práctico", IST, 15-17 January, Lisbon, Portugal.

1 - João M. Dias, Margarida Archer (1998): "Medição e processamento de dados cristalográficos (DENZO, SCALEPACK) - Análise Estrutural de Proteínas: um curso práctico", IST, 15-17 January, Lisbon, Portugal.

 

Scientific Communications - Reports and Conference Proceedings (20):

20 - T. Silva, João M. Dias, G. Bourenkov, H. Bartunik, I. Moura & M.J. Romão (2003): "Structure determination of a sixteen hemes Cytochrome from Desulfovibrio gigas", edited by Bartunik, H., Laasch, W., Lamzin, V., HASYLAB - DESY Annual Report 2002.

19 - D.R. Boer, H.C.A. Raaijmakers, João M. Dias, S. Bursakov, I. Moura, J.J.G. Moura & M.J.Romão (2002): "Crystal structure from the molybdenum-copper cofactor of the orange protein", Acta Cryst. A58 (Supplement), C117. (Conference Proceedings)

18 - S. Macieira, J. Rebelo, João M. Dias, R. Huber, C. S. Ascenso, F. Rusnak, J. J. G. Moura, I. Moura & M. J. Romão (2001): "Gene sequence and crystal structure of the aldehyde oxidoreductase from Desulfovibrio desulfuricans ATCC 27774 ", European Journal of Biochemistry (FEBS Annual Abstracts), Supplement 1, 268, 225.

17 - João M. Dias, C. Bonifácio, T. Alves, J.J.G. Moura, I. Moura & M.J. Romão, (2001): "Crystal structure of two pH dependent forms of a di-haem Cytochrome c Peroxidase from Pseudomonas nautica", European Journal of Biochemistry (FEBS Annual Abstracts), Supplement 1, 268, 186.

16 - Ana L. Carvalho, João M. Dias, Antonio Romero, Libia Sanz, Domingo Barettino, Juan J. Calvete and Maria J. Romão, (2001): "Protein Identification and Sequencing by Crystallography: the Crystal Structure of Horse Prostate Kallikrein at 1.42Å Resolution", European Journal of Biochemistry (FEBS Annual Abstracts), Supplement 1, 268, 1, 175.

15 - S. Teixeira, João M. Dias, A.L. Carvalho, M.J. Almendra, I. Moura, J.J.G. Moura, M.J. Romão, G. Bourenkov & H. Bartunik (1999): "Crystallographic Studies of D. gigas Formate Dehydrogenase", Acta Cryst, A55 (Supplement), 340. (Conference Proceedings)

14 - C.A. Cunha, João M. Dias, G. Almeida, C. Costa, J.J.G. Moura, I. Moura, M.J. Romão & A. Thompson (1999): "X-ray studies of a nitrite reductase: preliminary results", Acta Cryst, A55 (Supplement), 339. (Conference Proceedings)

13 - J.M. Rebelo, João M. Dias, M.J. Romão, G. Bourenkov, H. Bartunik & R. Huber (1999): "Refinement of the aldehyde oxido-reductase from Desulfovibrio gigas (MOP) at 1.28 Å", Acta Cryst, A55 (Supplement), 339. (Conference Proceedings)

12 - A.L. Carvalho, João M. Dias, S. Teixeira, G. Bourenkov, H. Bartunik, R. Huber, L. Maia, L. Mira & M. J. Romão (1999): "Crystallographic Studies on Xanthine Oxidase Purified from Rat Liver", Acta Cryst, A55 (Supplement), 339. (Conference Proceedings)

11 - M. J. Romão, A. L. Carvalho, João M. Dias, S. Teixeira, G. Bourenkov, H. Bartunik, R. Huber, L. Maia & L. Mira (1999): "Preliminary Crystallographic Studies on Xanthine Oxidase Purified from Rat Liver", Journal of Inorganic Biochemistry (ICBIC Book of Abstracts), 74, 281.

10 - João M. Dias, M.E. Than, R. Huber, G.P. Bourenkov, H.D. Bartunik, S. Bursakov, J.J.G. Moura, I. Moura & M.J. Romão, (1999): "Crystallographic studies of a dissimilatory nitrate reductase and mechanistic implications", Journal of Inorganic Biochemistry (ICBIC Book of Abstracts), 74, 113.

9 - S. Teixeira, J. M. Dias, A. L. Carvalho, G. Bourenkov, H. Bartunik, M. J. Almendra, I. Moura, J. J. G. Moura and M. J. Romão (1999): "Crystallographic Studies on a Tungsten-containing Formate Dehydrogenase from Desulfovibrio gigas", Journal of Inorganic Biochemistry (ICBIC Book of Abstracts), 74, 89.

8 - S.A. Bursakov, C. Brondino, João M. Dias, C. Carneiro, J. Caldeira, R.O. Duarte, M.J. Romão, I. Moura & J.J.G. Moura, (1999): "Cross immunological reactions and spectroscopy study within nitrate reductase and other mononuclear Mo containing enzymes of the sulfate reducing bacteria", Journal of Inorganic Biochemistry (ICBIC Book of Abstracts), 74, 86.

7 -S. Teixeira, João M. Dias, A.L. Carvalho, G. Bourenkov, H. Bartunik, M.J. Almendra ,I. Moura, J.J.G. Moura, M.J. Romão (1998): "Crystallographic studies of D. gigas Formate Dehydrogenase", edited by Bartunik, H., Laasch, W., Lamzin, V., HASYLAB - DESY Annual Report 1998.

6 - A. L. Carvalho, João M. Dias, S. Teixeira, G. Bourenkov, H. Bartunik, R. Huber, L. Maia, L. Mira & M.J. Romão (1998): "X-ray diffraction data collection of Xanthine Oxidase crystals purified from rat liver", edited by Bartunik, H., Laasch, W., Lamzin, V., HASYLAB - DESY Annual Report 1998.

5 - João M. Dias, M. Than, R. Huber, G. Bourenkov, H. Bartunik, S. Bursakov, I. Moura, J. Caldeira, J.J.G. Moura & M.J. Romão (1998): "Crystal structure of a periplasmic nitrate reductase (NAP) from Desulfovibrio desulfuricans at 1.8 Å resolution by MAD: a molybdopterin enzyme with a single Fe4S4 cluster", Bulletin of the Czech and Slovak Crystallographic Association, 5, 452. (Conference Proceedings)

4 - João M. Dias, M. Than, G. Bourenkov, H. Bartunik, R. Huber, S. Bursakov, I. Moura, J. Moura & M.J. Romão (1997): "MAD phasing of the 1.75 Å crystal structure of Desulfovibrio desulfuricans ATCC 27774 nitrate reductase", edited by Bartunik, H., Laasch, W., Lamzin, V., HASYLAB - DESY Annual Report 1997, 488-489.

3 - João M. Dias, M. Than, G. Bourenkov, H. Bartunik, R. Huber, S. Bursakov, I. Moura, J. Moura & M.J. Romão (1997): "Structural studies of a nitrate reductase from Desulfovibrio desulfuricans ATCC 27774", edited by Bartunik, H., Laasch, W., Lamzin, V., HASYLAB - DESY Annual Report 1997, 486-487.

2 - M.J. Romão, João M. Dias, J. Rebelo, G. Bourenkov, H. Bartunik, I. Moura, J. Moura & R. Huber (1997): "Atomic resolution data collection of the Xanthine Oxidase-Related Aldehyde Oxido-Reductase (MOP) from Desulfovibrio gigas", edited by Bartunik, H., Laasch, W., Lamzin, V., HASYLAB - DESY Annual Report 1997, 485.

1 - João M. Dias, C.C. Carneiro, M.J. Almendra, I. Moura, J. Moura, J. LeGall & Maria J. Romão (1996): "Crystallization and preliminary X-ray analysis of a nitrate reductase from Desulfovibrio desulfuricans ATCC 27774", Acta Cryst, A52 (Supplement). (Conference Proceedings)

 

Poster Presentations in Scientific Meetings (43)

43 - D.R. Boer, H.C.A. Raaijmakers, João M. Dias, S. Bursakov, I. Moura, J.J.G. Moura & M.J.Romão (2002): "Crystal structure from the molybdenum-copper cofactor of the orange protein", XIX International Union of Crystallography Congress (XIX IUCr), 6-15 August, Geneva, Switzerland.

42 - João M. Dias, C. Bonifácio, T. Alves, J.J.G. Moura, I. Moura & M.J. Romão (2001): "Crystal structure of two pH-dependent forms of a di-haem cytochrome c peroxidase from Pseudomonas nautica", 2nd Meeting RequiMte, CQFB-CEQUP, 28-29 September, Caparica, Portugal.

41 - A.L. Carvalho, João M. Dias, A. Romero, L. Sanz, D. Barettino, J.J. Calvete & M.J. Romão (2001): "Protein identification and sequencing by crystallography: the crystal structure of horse prostate kallikrein at 1.42 Å resolution", 2nd Meeting RequiMte, CQFB-CEQUP, 28-29 September, Caparica, Portugal.

40 - C.A. Cunha, João M. Dias, G. Almeida, S. Macieira, J.J.G. Moura, I. Moura & M.J. Romão (2001): "The crystal structure of membrane bound cytochrome c nitrite reductase from Desulfovibrio desulfuricans at 2.3 Å", 2nd Meeting RequiMte, CQFB-CEQUP, 28-29 September, Caparica, Portugal.

39 - João M. Dias, C. Bonifácio, T. Alves, J.J.G. Moura, I. Moura & M.J. Romão (2001): "Crystal structure of two pH-dependent forms of a di-haem cytochrome c peroxidase from Pseudomonas nautica", 20th European Crystallographic Meeting (ECM 20), 25-31 August, Krakow, Poland.

38 - A.L. Carvalho, João M. Dias, A. Romero, L. Sanz, D. Barettino, J.J. Calvete & M.J. Romão (2001): "Protein identification and sequencing by crystallography: the crystal structure of horse prostate kallikrein at 1.42 Å resolution", 20th European Crystallographic Meeting (ECM 20), 25-31 August, Krakow, Poland.

37 - C.A. Cunha, João M. Dias, G. Almeida, S. Macieira, J.J.G. Moura, I. Moura & M.J. Romão (2001): "The crystal structure of membrane bound cytochrome c nitrite reductase from Desulfovibrio desulfuricans at 2.3 Å", 20th European Crystallographic Meeting (ECM 20), 25-31 August, Krakow, Poland.

36 - S. Macieira, J. Rebelo, João M. Dias, R. Huber, C. Ascenso, F. Rusnak, J.J.G. Moura, I. Moura & M.J. Romão (2001): "Gene sequence and crystal structure of the aldehyde oxidoreductase from Desulfovibrio desulfuricans ATCC 27774", 27th Fed. Eur. Biochemical Society Meeting, FEBS-PABMB-SPB, 30 June-5 July, Lisboa, Portugal.

35 - A.L. Carvalho, João M. Dias, A. Romero, L. Sanz, D. Barettino, J.J. Calvete & M.J. Romão (2001): "Protein identification and sequencing by crystallography: the crystal structure of horse prostate kallikrein at 1.42 Å resolution", 27th Fed. Eur. Biochemical Society Meeting, FEBS-PABMB-SPB, 30 June-5 July, Lisboa, Portugal.

34 - João M. Dias, C. Bonifácio, T. Alves, J.J.G. Moura, I. Moura & M.J. Romão (2001): "Crystal structure of two pH-dependent forms of a di-haem cytochrome c peroxidase from Pseudomonas nautica", 27th Fed. Eur. Biochemical Society Meeting, FEBS-PABMB-SPB, 30 June-5 July, Lisboa, Portugal.

33 - A.L. Carvalho, João M. Dias, Antonio Romero, Juan J. Calvete & M.J. Romão (2001): "Protein Identification and Sequencing by Crystallography: The crystal structure of horse prostate kallikrein at 1.42 Å resolution", Dia da Química, Dep. Química da FCT-UNL, 2 May, Monte de Caparica, Portugal.

32 - C.A. Cunha, João M. Dias, G. Almeida, C. Costa, A. Thompson, J.J.G. Moura, I. Moura & M.J. Romão (2001): "Crystallographic Studies of D. desulfuricans ATCC 27774 Nitrite Reductase", Dia da Química, Dep. Química da FCT-UNL, 2 May, Monte de Caparica, Portugal.

31 - H. Raaijmakers, S. Teixeira, João M. Dias, A.L. Carvalho, S. Bursakov, M.J. Almendra, I. Moura, J. Moura & M.J. Romão (2000):"Desulfovibrio gigas Formate Dehydrogenase: Use of Tungsten anomalous scattering to solve a 2x(88+29) kDa protein", International School of Crystallography, 31st Course, "Chemical Prospectives in Crystallography of Molecular Biology", 25 May – 4 June, Erice, Italy.

30 - A.L. Carvalho, João M. Dias, Antonio Romero, Juan J. Calvete & M.J. Romão (2000): "Protein Identification and Sequencing by Crystallography: The crystal structure of horse prostate kallikrein at 1.42 Å resolution", "Methods in Macromolecular Crystallography", 30st Course of International School of Crystallography, 25 May – 4 June, Erice, Italy.

29 - S. Teixeira, João M. Dias, A.L. Carvalho, M.J. Almendra, I. Moura, J.J.G. Moura, M.J. Romão, G. Bourenkov & H. Bartunik (1999): "Crystallographic Studies of D. gigas Formate Dehydrogenase", XVIII International Union of Crystallography Congress (XVIII IUCr), 4-13 August, Glasgow, Scotland.

28 - C.A. Cunha, João M. Dias, G. Almeida, C. Costa, J.J.G. Moura, I. Moura, M.J. Romão & A. Thompson (1999): "X-ray studies of a nitrite reductase: preliminary results", XVIII International Union of Crystallography Congress (XVIII IUCr), 4-13 August, Glasgow, Scotland.

27 - J.M. Rebelo, João M. Dias, M.J. Romão, G. Bourenkov, H. Bartunik & R. Huber (1999): "Refinement of the aldehyde oxido-reductase from Desulfovibrio gigas (MOP) at 1.28 Å", XVIII International Union of Crystallography Congress (XVIII IUCr), 4-13 August, Glasgow, Scotland.

26 - A.L. Carvalho, João M. Dias, S. Teixeira, G. Bourenkov, H. Bartunik, R. Huber, L. Maia, L. Mira & M.J. Romão (1999): "Crystallographic Studies on Xanthine Oxidase Purified from Rat Liver", XVIII International Union of Crystallography Congress (XVIII IUCr), 4-13 August, Glasgow, Scotland.

25 - M.J. Romão, A.L. Carvalho, João M. Dias, S. Teixeira, G. Bourenkov, H. Bartunik, R. Huber, L. Maia & L. Mira (1999): "Preliminary Crystallographic Studies on Xanthine Oxidase Purified from Rat Liver", 9th International Conference on Biological Inorganic Chemistry (ICBIC 9), 11-16 July, University of Minnesota, Minneapolis, Minnesota, U.S.A.

24 - João M. Dias, M.E. Than, R. Huber, G.P. Bourenkov, H.D. Bartunik, S. Bursakov, J.J.G. Moura, I. Moura & M.J. Romão (1999): "Crystallographic studies of a dissimilatory nitrate reductase and mechanistic implications", 9th International Conference on Biological Inorganic Chemistry (ICBIC 9), 11-16 July, University of Minnesota, Minneapolis, Minnesota, U.S.A.

23 - S. Teixeira, João M. Dias, A.L. Carvalho, G. Bourenkov, H. Bartunik, M.J. Almendra, I. Moura, J.J.G. Moura, M.J. Romão (1999): "Crystallographic studies on tungsten-containing formate dehydrogenase from Desulfovibrio gigas", 9th International Conference on Biological Inorganic Chemistry (ICBIC 9), 11-16 July, University of Minnesota, Minneapolis, Minnesota, U.S.A.

22 - S.A. Bursakov, C. Brondino, João M. Dias, C. Carneiro, J. Caldeira, R.O. Duarte, M.J. Romão, I. Moura & J.J.G. Moura (1999): “Cross immunological reactions and spectroscopy study within nitrate reductase and other mononuclear Mo containing enzymes of the sulfate reducing bacteria”, 9th International Conference on Biological Inorganic Chemistry (ICBIC 9), 11-16 July, University of Minnesota, Minneapolis, Minnesota, U.S.A.

21 - M. Than, A. Bergner, João M. Dias, M.J. Romão & R. Huber (1999): "Cluster phasing via PC-refinement: Application to MIR and MAD cases", 5th European Workshop on Crystallography of Biological Macromolecules, 16-20 May, Como, Italy.

20 - S. Teixeira, João M. Dias, A.L. Carvalho, G. Bourenkov, H. Bartunik, M.J. Almendra, I. Moura, J. Moura & M.J. Romão (1999): "Crystallographic Studies of D. gigas Formate dehydrogenase", 1st Meeting RequiMte, CQFB-CEQUP, 5-6 February, Porto, Portugal.

19 - J.M. Rebelo, João M. Dias, J.J.G. Moura, G.P. Bourenkov, H.D. Bartunik, R. Huber & M.J. Romão (1999): "Refinement of the Aldehyde Oxidoreductase from Desulfovibrio gigas (MOP) at 1.28 Å", 1st Meeting RequiMte, CQFB-CEQUP, 5-6 February, Porto, Portugal.

18 - Carlos A. Cunha, João M. Dias, Gabriela Almeida, Cristina Costa, Andrew Thompson, José J.G. Moura, Isabel Moura & Maria J. Romão (1999): "X-Ray Studies of a Nitrite Reductase: Preliminary Results", 1st Meeting RequiMte, CQFB-CEQUP, 5-6 February, Porto, Portugal.

17 - A.L. Carvalho, João M. Dias, S. Teixeira, G. Bourenkov, H. Bartunik, R. Huber, L. Maia, L. Mira & Maria J. Romão (1999): "Preliminary Crystallographic Studies of Xanthine Oxidase Purified Rat Liver", 1st Meeting RequiMte, CQFB-CEQUP, 5-6 February, Porto, Portugal.

16 - S. Teixeira, João M. Dias, A.L. Carvalho, H. Bartunik, M.J. Almendra, I. Moura, J.J.G. Moura & M.J. Romão (1998): "Crystallographic studies on D. gigas Formate Dehydrogenase", XI Congresso Nacional de Bioquímica, SPB, 28-30 November, Tomar, Portugal.

15 - João M. Dias, M. Than, A. Humm, R. Huber, G. Bourenkov, H. Bartunik, S. Bursakov, J. Calvete, J. Caldeira, C. Carneiro, J.J.G. Moura, I. Moura & Maria J. Romão (1998): "Crystal Structure of a Periplasmic Nitrate Reductase from Desulfovibrio desulfuricans ATCC 27774 solved by Multiwavelength Anomalous Diffraction methods", XI Congresso Nacional de Bioquímica, SPB, 28-30 November, Tomar, Portugal.

14 - João M. Dias, M. Than, A. Humm, R. Huber, G. Bourenkov, H. Bartunik, S. Bursakov, J. Calvete, J. Caldeira, C. Carneiro, J.J.G. Moura, I. Moura & M.J. Romão (1998): "Crystal Structure of a Periplasmic Nitrate Reductase (NAP) from Desulfovibrio desulfuricans ATCC 27774 solved by MAD Methods", Structure and Function of Metalloproteins, ISTAS, ITQB, 6-19 September, Oeiras, Portugal.

13 - João M. Dias, M. Than, R. Huber, G. Bourenkov, H. Bartunik, S. Bursakov, I. Moura, J. Caldeira, J.J.G. Moura & M.J. Romão (1998): "Crystal Structure of a Periplasmic Nitrate Reductase (NAP) from Desulfovibrio desulfuricans ATCC 27774 at 1.8 Å resolution by MAD: a molybdopterin enzyme with a single Fe4S4 cluster", XVIII European Crystallography Meeting, IUCr, 16-20 August, Prague, Czech Republic.

12 - João M. Dias, M. Than, A. Humm, R. Huber, G. Bourenkov, H. Bartunik, S. Bursakov, J. Calvete, J. Caldeira, C. Carneiro, J.J.G. Moura, I. Moura & M.J. Romão (1998): "Crystal Structure of a Periplasmic Nitrate Reductase (NAP) from Desulfovibrio desulfuricans ATCC 27774 solved by MAD Methods", Spectroscopy and Engineering of Metalloproteins, ISTAS, ITQB, 6-19 July, Oeiras, Portugal.

11 - João .M. Dias, M. Than, R. Huber, G. Bourenkov, H. Bartunik, S. Bursakov, I. Moura, J. Caldeira, J.J.G. Moura, M.J. Romão (1998): "Crystal Structure of a Periplasmic Nitrate Reductase(NAP) from Desulfovibrio desulfuricans ATCC 27774", Symposium on Inorganic Biochemistry and Regulatory Mechanisms of Iron Metabolism, Sintra, Portugal.

10 - João M. Dias, Sergey Bursakov, I. Moura, J. Moura, C. Carneiro & Maria J. Romão (1998): "Crystallisation and Preliminary X-Ray Analysis of a Nitrate Reductase from Desulfovibrio desulfuricans ATCC 27774", HERCULES - Neutron and Synchrotron Radiation for Biomolecular Structure and Dynamics, ESRF, ILL, LURE, LLB, Grenoble and Paris, France.

9 - Ana L. Carvalho, João M. Dias, I. Kölln, A. Romero, P. Varela, L. Sanz, E.T. Petersen, J.J.Calvete, M.J. Romão (1997): "Crystal Structure of the bovine acidic seminal fluid protein (aSFP):a growth factor for granulosa cells, with a single CUB domain architecture", XVII European Crystallography Meeting, IUCr, Lisboa, Portugal.

8 - João M. Dias, Sergey Bursakov, I. Moura, J. Moura, C. Carneiro & Maria J. Romão (1997): "Crystallisation and Preliminary X-Ray Analysis of a Nitrate Reductase from Desulfovibrio desulfuricans ATCC 27774", XVII European Crystallography Meeting, International Union of Crystallography, Lisboa, Portugal.

7 - João M. Dias, Sergey Bursakov, I. Moura, J. Moura, C. Carneiro & Maria J. Romão (1997): "Crystallisation and Preliminary X-Ray Analysis of a Nitrate Reductase from Desulfovibrio desulfuricans ATCC 27774", Chemistry of Metals in Biological Systems, SBIC, Tomar, Portugal.

6 - João M. Dias, Sergey Bursakov, I. Moura, J. Moura, C. Carneiro & Maria J. Romão (1997): "Crystallisation and Preliminary X-Ray Analysis of a Nitrate Reductase from Desulfovibrio desulfuricans ATCC 27774", Molybdenum Enzymes Meeting, University of Sussex, Sussex, England.

5 - M.J. Romão, I. Kölln, João M. Dias, A.L. Carvalho, A. Romero, P. Varela, L. Sanz, E.T. Petersen & J.J. Calvete (1997): "Crystal Structure of the bovine acidic seminal fluid protein (aSFP): a growth factor for granulosa cells, with a single CUB domain architecture", Workshop on Cellular Interactions During Mammalian Oogenesis and Fertilization, Instituto Gulbenkian Ciência, Oeiras, Portugal.

4 - João M. Dias, C. Carneiro, M.J. Almendra, I. Moura, J. Moura, J. LeGall & Maria J. Romão (1996): "Crystallisation and Preliminary X-Ray Analysis of a Nitrate Reductase from Desulfovibrio desulfuricans ATCC 27774", Understanding Protein Structure, Karolinska Institutet, Novum Research Park, Stockholm, Sweden.

3 - João M. Dias, C. Carneiro, M.J. Almendra, I. Moura, J. Moura, J. LeGall & Maria J. Romão (1996): "Crystallization and Preliminary X-Ray Analysis of a Nitrate Reductase from Desulfovibrio desulfuricans ATCC 27774", XVII Congress and General Assembly of International Union of Crystallography, IUCr, Seattle, USA.

2 - João M. Dias, C. Carneiro, M.J. Almendra, I. Moura, J. Moura, J. LeGall & Maria J. Romão (1996): "Cristalização e Estudos Preliminares da Difracção de Raios X de uma Reductase do Nitrato de Desulfovibrio desulfuricans ATCC 27774", XV Encontro Nacional da Sociedade Portuguesa de Química, Sociedade Portuguesa de Química, Porto, Portugal.

1 - Carlos Frazão, João M. Dias, Joosé Morais, Pedro M. Matias, Maria J. Romão, Maria A. Carrondo, Emkhe Poll, George Sheldrick, Zbigniew Dauter & Keith Wilson (1994): "Crystallographic Analysis of Cytochrome c6 from Monoraphidium braunii", I European Conference on Synchrotron Radiation in Biological and Medical Sciences, Espinho, Portugal.



Participation in Scientific Meetings (50)

June 2003 - "E-MSD Workshop. New web-based tools for PDB analysis", EBI, 26 June, ITQB, Oeiras, Portugal.

February 2003 - "Workshop on Phasing with soft X-Rays", Elettra, ESBF, 25-27 February, Bressanone-Brixen, Italy.

January 2003 - "Experimental Phasing - CCP4 Study Weekend", University of York, 3-4 January, York, England.

December 2002 - "MAXINF Course - Data Collection and Processing", MRC Laboratory of Molecular Biology, 2-6 December, Cambridge, England.

August 2002 - "XIX International Union of Crystallography Congress (XIX IUCr)", 6-15 August, Geneva, Switzerland.

October 2001 - Proteins: from structure to dynamics, 3rd Short Course of the Portuguese Biophysical Society, 4-6 October, Santarém, Portugal.

September 2001 - 2nd Meeting RequiMte, CQFB-CEQUP, 28-29 September, Caparica, Portugal.

August 2001 - "20th European Crystallographic Meeting (ECM 20)", 25-31 August, Krakow, Poland.

June/July 2001 - "27th Fed. Eur. Biochemical Society Meeting", FEBS-PABMB-SPB, 30 June-5 July, Lisboa, Portugal.

May 2001 - "Ciência Viva", Fundação da Ciência e Tecnologia, Ministério da Ciência e Tecnologia, 11-12 May, Lisboa, Portugal.

May 2001 - "Dia da Química", Dep. Química da Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa, 2 May, Monte de Caparica, Portugal.

March 2001 - "Metalloenzymes and Chemical Biomimetics", COST Network Meeting, COST Action D21, 31 March – 1 April, Monte de Caparica, Portugal.

March 2001 - "COST D21 Meeting – 3rd Meeting of the Management Committee, Mettalloenzymes and Chemical Biomimetics", 2-4 March, Hotel Tivoli, Sintra, Portugal.

July 2000 - "EC Network Meeting on Pteridines", Max Planck Institut für Biochemie, 7-8 July, Martinsried, Munich, Germany.

May 2000 - "Chemical Prospectives in Crystallography and Molecular Biology", 31st Course of International School of Crystallography, 25 May – 4 June, Erice, Italy.

May 2000 - "Methods in Macromolecular Crystallography", 30st Course of International School of Crystallography, 25 May - 4 June, Erice, Italy.

August 1999 - "XVIII International Union of Crystallography Congress (XVIIIth IUCr)", 4-13 August, Glasgow, Scotland.

July 1999 - "9th International Conference on Biological Inorganic Chemistry (ICBIC 9)", 11-16 July, University of Minnesota, Minneapolis, Minnesota, U.S.A.

May 1999 - "5th European Workshop on Crystallography of Biological Macromolecules", 16-20 May, Como, Italy.

February 1999 - "1st Meeting RequiMte", CQFB-CEQUP, 5-6 February, Porto, Portugal.

January 1999 - "Data Collection and Processing - CCP4 Study Weekend", Daresbury Laboratory, Sheffield University, 8-9 January, Sheffield, England.

December 1998 - "II Congresso Luso-Espanhol de Biofísica, VI Congreso de la Sociedad de Biofísica de España", 4-7 December, Madrid, Spain.

November 1998 - "XI Congresso Nacional de Bioquímica",, Sociedade Portuguesa de Bioquímica, 28-30 November, Tomar, Portugal.

September 1998 - "Structure and Function of Metalloproteins", ISTAS, ITQB, 7 a 19 September, Oeiras, Portugal.

August 1998 - "XVIII European Crystallography Meeting", International Union of Crystallography, 15-20 August, Prague, Czech Republic.

July 1998 - "Spectroscopy and Engineering of Metalloproteins", ISTAS, ITQB, 6 a 19 July, Oeiras, Portugal.

June 1998 - "Symposium on Inorganic Biochemistry and Regulatory Mechanisms of Iron Metabolism", Sintra, Portugal.

February/April 1998 - "HERCULES - Neutron and Synchrotron Radiation for Biomolecular Structure and Dynamics", ESRF, ILL, LURE, LLB, 22 February - 3 April, Grenoble and Paris, France.

January 1998 - "Análise Estrutural de Proteínas: um curso práctico", IST, 15-17 January, Lisboa, Portugal.

January 1998 - "Databases for Macromolecular Crystallographers - CCP4 Study Weekend", Daresbury Laboratory, Reading University, 9-10 January, Reading, England.

August 1997 - "Validation and Refinement of Macromolecular Structures Meeting", XVII ECM Sattelite Meeting, ICBAS, 29-30 August, Porto, Portugal.

August 1997- "XVII European Crystallography Meeting", International Union of Crystallography, 24-28 August, Lisboa, Portugal.

August 1997- Workshop: "New Trends in Molecular Crystallization", IUCr, XVII ECM, 23 August, Lisboa, Portugal.

May 1997 - "Chemistry of Metals in Biological Systems", SBIC, 7-10 May, Tomar, Portugal.

April 1997 - "Molybdenum Enzymes Meeting", University of Sussex Meeting, 12-15 April, Sussex, England.

September 1996 - Workshop: "Understanding Protein Structure Determination", Karolinska Institutet, Novum Research Park, 1-6 September, Stockholm, Sweden.

August 1996 - "XVII Congress and General Assembly of International Union of Crystallography", IUCr, 8-17 August, Seattle, USA.

May 1996 - "XV Encontro Nacional da Sociedade Porrtuguesa de Química", Sociedade Portuguesa de Química, 22-25 May, Porto, Portugal.

January 1996 - "Macromolecular Refinement - CCP4 Study Weekend", Daresbury Laboratory, Chester College, 5-6 January, Chester, England.

December 1995 - "I Congresso Luso-Espanhol de Biofísicca, V Congreso de la Sociedad de Biofísica de España", 4-7 December, Lisboa, Portugal.

October 1995 - "Sym95 Summer School - From the symmetry of the molecule to the crystal organisation - fundamental tools and applications", Université Montpellier and CEMES-LOE (UPR 8011 du CNRS) Toulouse, 21-28 October, Bagnères-de-Luchon, France.

October 1995 - "Chemistry Workshop for IB Teachers", International Baccalaureate Organization, 20 e 21 October, Madrid, Spain.

October 1995 - "EC Network Meeting on Pteridines: Biosynthesis, Regulation, and Pharmacology", Instituto de Tecnologia e Química Biológica, 12-15 October, Oeiras, Portugal.

September 1995 - "Simpósio 100 Anos da Descoberta dos Raios X - A Radiação X na Sociedade e no Desenvolvimento Científico", Universidade Nova de Lisboa, 28-30 September, Lisboa, Portugal.

July 1994 - "III European Summer Workshops for inexperienced or prospective IB Teachers (Chemistry)", International Baccalaureate Organization, 11-15 July, Prague, Czech Republic.

May 1994 - "I European Conference on Synchrotron Radiation in Biological and Medical Sciences", 4-7 May, Espinho, Portugal.

June 1993 - "I Congresso de Radicais Livres em Química, Biologia e Medicina", Sociedade Portuguesa de Química, Sociedade Portuguesa de Radicais Livres, 21-23 June, Lisboa, Portugal.

November 1992 - "Curso de Introdução ao Sistema VAX/VMS", Centro de Informática do Instituto Superior Técnico, Universidade Técnica de Lisboa, November, Lisboa, Portugal.

September 1992- "II Escola Ibero-Americana de Cristalografia", Consejo Superior de Investigaciones Científicas, 14-18 September, Madrid, Spain.

January 1992 - "Proteínas - Aspectos Estruturais e Funcionais", Jornadas da Sociedade Portuguesa de Bioquímica, 17-18 January, Coimbra, Portugal.


Other activities

        - Administration member and founder of "Académico Clube de Ciências" (1996).

        - Football and futsal coach, Level I of "Federação Portuguesa de Futebol" (1995).

        - Music course - Level 7, Keyboards "Electone Yamaha", Valentim de Carvalho, Lisboa (1986-1991).

        - Adventure, travelling, sports, reading, music.


 

This page was last updated on 29-08-2006.

1