The smears show cellularity of high grade non-Hodgkin lymphoma. Immunophenotyping revealed a B-cell lymphoma. Extensive work up did not reveal lymphadenopathies or other organ involvement, alpha fetoprotein level was not elevated. Negative serology for HIV and HCV. The case has been considered a primary hepatic lymphoma, a quite rare entity. To our knowledge is the fifth case diagnosed by FNA cytology. The other cases were reported by

Netto D, Spielberger R, Awasthi S, Balaban EP, Nowak JA, Demian SD. Primary lymphoma of the liver. Report of a case with diagnosis by fine needle aspiration. Acta Cytol. 1993;37(4):515-519.

Rappaport KM, DiGiuseppe JA, Busseniers AE. Primary hepatic lymphoma: report of two cases diagnosed by fine-needle aspiration. Diagn Cytopathol. 1995;13(2):142-145.

Cai G, Inghirami G, Moreira A, Sen F. Primary hepatic anaplastic large-cell lymphoma diagnosed by fine-needle aspiration biopsy. Diagn Cytopathol. 2005;33:106-109. This case had T-cell immunophenotype and was immunoreactive with CD30 antibody.