Drs. Prolla and Diehl's INTERESTING CASE OF THE MONTH June 2007 case
CSF, Cytospin preparation: metastatic retinoblastoma

Metastatic retinoblastoma, single small cells, with numerous loose groups showing nuclear molding with “salt and pepper“ chromatin, small or absent nucleoli; a pseudo-rosette. 200x Pap staining

Metastatic retinoblastoma, higher power view of previous picture: notice the pseudo-rosette,in the center. 500x Pap staining

Metastatic retinoblastoma, notice another pseudo-rosette, 500x Pap staining

Metastatic retinoblastoma, single small cells, with numerous loose groups showing nuclear molding. The nuclei are oval or angulated, many apoptotic bodies, 200x Pap staining

Metastatic retinoblastoma, notice another pseudo-rosette, 500x Pap staining

The smears show the typical features of small blue cell tumors: single small cells, with numerous loose groups showing nuclear molding. The nuclei are oval or angulated, with "salt and pepper" chromatin, small or absent nucleoli. The cytoplasm is scant or almost absent, a faint bluish line between the nuclei. Several pseudo-rosettes were seen. Few mitoses also were seen, as well as apoptotic cells and bodies.





Case June 2007 References List of cases Atlas
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