6:00 A.M.-7:00 A.M.

As the hotel guests grow sickly, Michelle offers up suicide pills to the afflicted people. One of the guests reveals that the man she shared a one-night stand with has escaped from the hotel. Michelle finds the man’s fingerprint and they track down his identity. Michelle breaks down to Tony, letting him know that she loves him.

5:00 A.M.-6:00 A.M.

Michelle tries to keep the panicked hotel guests calm. She has Alvers describe his employer to CTU, and they run a cross-check with Jack's files. Alvers picks out Saunders from a photograph. Michelle goes to see Gael in isolation, and offers her dying friend a gun to put himself out of his misery. Michelle is sad when Gael passes and she begs Tony to send over suicide capsules for the virus-infected people.

4:00 A.M.-5:00 A.M.

Michelle gets Alvers to divulge that there are eleven other vials of the virus. He also had added an accelerant to lessen the incubation period of the virus, and Gael already starts to show symptoms. Michelle has her team jam cell phone signals and lock up all exits of the hotel. When a bellhop sets off a fire alarm, Michelle tries to contain the guests by lying about the situation. The bellhop tries to escape, and Michelle convinces him that he will put others in danger if he leaves. When other guests start to display symptoms, one man breaks open the glass door. Michelle is forced to shoot the man to prevent him from exiting the building.

3:00 A.M.-4:00 A.M.

Because of her experience in the field, Chappelle assigns Michelle to lead the team on site where the virus may have been unleashed. There’s still some friction between her and Tony, but Gael says that Tony had been upset that he couldn’t confide in her about their secret Salazar mission. Tony orders Michelle not to enter the building until she has a biohazard suit to safeguard her, but when evidence shows that they might be too late, she goes in without protection. Inside the hotel, Michelle takes down Alvers and she gets him to reveal that the virus has been put in the ventilation duct. She radios Gael to go find it.

2:00 A.M.-3:00 A.M.

Tony points the finger at Michelle when a lapse in research during her tenure as Acting Director causes some delay. Michelle has a valid excuse, but she is angry with Tony for blaming her so publicly. Yet she tells Tony that the two of them are fine. Michelle diligently works to prepare the interrogation even though Tony will be grilling a woman who he once slept with. When Nina comments about Tony's wedding ring, Michelle instinctively flinches.

1:00 A.M.-2:00 A.M.

Michelle makes it possible for Division to assist in the search for Amador's associate, Alvers.

12:00 A.M.-1:00 A.M.

There is still some lingering tension between Michelle and Tony. He is brusque towards her.

11:00 P.M.-12:00 A.M.

Michelle receives a call from Jack, but he doesn’t speak. She puts it on speaker so that Tony can hear him discuss with the Salazars the location of the virus transaction. When Chappelle suspends Chloe for bringing her baby to work, Michelle reminds him that they need her to take care of the digitally enhanced audio surveillance in Mexico. Michelle wisely advises that they deal with Chloe’s childcare issues another time.

10:00 P.M.-11:00 P.M.

Michelle comes to Tony to apologize for not trusting his abilities. Tony feels she only did it to prove her resolve to CTU. Yet before she can explain herself, Tony turns back to work.

9:00 P.M.-10:00 P.M.

After Kim lets her know about Tony’s mistakes Michelle becomes suspicious of her husband’s competency. She warns Chappelle, who questions Tony. Michelle is embarrassed when Tony has relevant excuses for the mistakes he supposedly made.

8:00 P.M.-9:00 P.M.

Michelle notices that Tony is still weak, but he refuses to go back to the hospital. Tony apologizes for not telling her the truth about Jack’s secret mission, but Michelle is upset that she didn’t recognize that Tony was keeping something from her for over a month.

7:00 P.M.-8:00 P.M.

Michelle is trying to leave the office to go to the hospital to see Tony, but she is pulled into one briefing after another. After Gael is taken into custody and tortured in interrogation, she hurries to Tony's side. Tony insists that he immediately return to work, and asks Michelle to trust his judgment. She signs him out of the hospital, and takes him back to CTU. Tony asks that she and Chappelle leave him alone with Gael. Although Michelle doesn't know what his reasons are, she obeys Tony's wishes.

6:00 P.M.-7:00 P.M.

Ryan Chappelle takes over command of CTU from Michelle, and he orders Jack to be shot down because they no longer need Salazar. When Jack eludes the military by landing in the middle of a downtown street, CTU changes its strategy and must now capture Jack on the ground. Michelle tries to ease Kim's anxiety by telling her there's a better chance they can get Salazar without harming Jack now that he's on the ground. Michelle is relieved when she learns that Tony is out of surgery and is expected to make a full recovery. Yet she continues with her work, and asks Gael to come see her so that she can assign him to a new task.

5:00 P.M.-6:00 P.M.

Michelle must play mediator when she makes Adam ease up on Kim. She then asks Chloe to search Jack's office, where Chloe finds drugs and heroin paraphernalia in the wastebasket. Michelle gets a feed to the camera in Tony's surgery and she is shaken by the sight of her husband being operated on. After the truck carrying Kyle Singer is spotted at an industrial complex, Michelle orders a raid. She calls Chase immediately after Kyle is captured by CTU.

4:00 P.M.-5:00 P.M.

Michelle gives authorization for the doctors to perform surgery on Tony, but she decides to stay at CTU instead of being with him at the hospital. She is the only one who can take over his command. After receiving another call with demands for Salazar’s release, Gael offers to take over her job so that she can be with her husband. Michelle refuses, unaware that Gael is up to nefarious mole activities.

3:00 P.M.-4:00 P.M.

After figuring out that the call demanding Salazar’s release came from inside the U.S., Michelle asks Gael to help her narrow down the location. She is unaware that he is the traitor who placed the call and he is the one keeping Hector Salazar abreast of CTU’s findings.

2:00 P.M.-3:00 P.M.

Michelle learns from Dr. Macer that the virus was delivered through a powdered substance resembling cocaine or heroin. She then gives Jack the last known address of the body identified as Goss. Per Tony’s order, she makes sure Jack and Chase are wired for transmitters when they go to find Goss’s connection to Salazar. Kim comes to Michelle for advice on dealing with an office romance, and Michelle tells her to keep it between her and Chase.

1:00 P.M.-2:00 P.M.