| Disease | Symptoms | Cure |
| Neogitus | Sore and swollen gums. Difficulty eating or drinking. | Brush with a Medicinal Toothbrush |  |
| Bloaty Belly | Your pet ate too much, bloated and wont eat. | Feed Flat-u-less Tablets |  |
| Fuzzitus | Allergy to fluff, especially bad for JubJubs!! | Shake Fluff Be Gone on their fur |  |
| Achy Head | Pet will have a nasty headache and feel under the weather. | Rub some Magic Goop on their head |  |
| Shock -A- Lots | Pet's fur will be full of static, gives off electric sparks. | Wear Ultra Rubber Gloves |  |
| Watery Eyes | Pet looks like it is constantly crying, even when happy. | Rub Onion Balm around their eyes |  |
| NeoBlues | Pet is feeling down, won't play or eat, or very little. | A Tasty Pie will cheer them!!! |  |
| Floppy Tongue | Tongue is swollen and floppy. Can't close mouth, drools. | Tongue Shrinker Injection |  |
| Cricky Neck | Ouch - your pet's neck is stiff and can't move its head. | Wear a special Neck Brace |  |
| NeoMites | Coat is covered with lurgees that hop, your pet scratches. | Give them a NeoMites Injection |  |
| Blurred Vision | Pet sees spots and may bump into things all the time. | Wearing Extra Thick Goggles |  |
| Neggitus | Too many Neggs, swelling ears and dizziness | Give them a Neggitus Injection |  |
| Sneezles | Your pet will have a runny nose and sneeze constantly. | Give them a Magic Cookie |  |
| D'achoo | Pet goes into a sneezing fit, and its eyes become sore. | Wipe their nose with Neopkins |  |
| Shaky Flakys | Pet trembles and skin is dry. If bad skin may flake off. | Rub Shaky Flaky Cream on skin |  |
| Grumbles | Stomach makes loud noises and it may be from its food | Take four Grumble Be Gone Tablets |  |
| Chickaroo | Pet thinks it is a chicken, pecking the ground and crowing. | Feed Herbal Scrambled Eggs |  |
| Bloaty Feet | Your pet's feet will swell and grow in size. | Wear Magic Smelly Socks |  |
| Kikoughela | Your pet will have a sore throat and coughing fits. | 2 spoonfuls Kikoughela Syrup |  |
| Lumps | Your pet will be covered in large, yellow, itchy lumps. | Give them a Medicinal Mud Bath |  |
| NeoPhobia | A chronic fear of leaving the house. | Make wear Step Out Shoes |  |
| Hoochie Coochies | Pet will break out in blue and green spots. | Give Hoochie Coochie Tablets |  |
| NeoMonia | Pet feels sick, tired, and grumpy until cured. | Bathe with Medicinal Soap |  |
| Neezles | Pet breaks out in red spots. | Give them a Neezles Jab |  |
| Itchy Scratchies | Pet is covered in amazingly itchy red lumps. | Itchy Scratchy Cream |  |
| NeoPox | Pet will be covered in itchy,red blotches | Feed slice of NeoPox Pizza |  |
| NeoWarts | Pet has big cauliflower like lumps on its body. | Feed Neowart Fungus |  |
| Bubbles | Your poor pet will constantly hiccup bubbles. | Bubbles Herbal Drink |  |
| Neo Flu | Pet refuses to eat, appears flushed and very sleepy. | Handful of Neoflu Jelly Pills. |  |
| Fuzzy Fungus | Neopets fur turns purple as it turns into a Fungus Ball. | Honey Blossom Extract |  |
| Ugga-Ugga | Pets throat swells and can only makes Ugga noises. | Warm cup of Sporkle Syrup. |  |
| Reptillioritus | Skin is red and itchy, won't eat and tired. | Cactopus Cream on area. |  |
| Doldrums | Pet hides in cold, dark corners and won't come out. | Rub Mushroom Ointment on. |  |
| Jitters | Pet can't sit still to sleep, eat or do anything. | Feed your pet Potion of Containment |  |
| Spyder Bite | Pets afraid of the Spider Grundo and Spyders. | Feed Spyder Juice Elixir. |  |