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Cellular Respiration
(C6H12O6 + 6O2 ��> 6CO2 + 6H2O + energy)

 
(Glucose)

Index:
What is Cellular Respiration?
Synopsis of Cellular Respiration
Stages of Cellular Respiration in more Detail

What Cellular Respiration is

            Cellular Respiration is the process where living organisms gathers the energy in food molecules to make energy. Heterotrophs, organisms that must get energy from food indirectly from sunlight or inorganic substances, go through the process of cellular respiration to get the energy needed. This energy comes from food. Heterotrophs, including humans and other animals, undergo Cellular Respiration, where the energy contained in food is released to make ATP, which provides cells with the energy needed to carry out the processes of life. Cellular Respiration takes place in a living body of a heterotroph. In cellular respiration, there are anaerobic and aerobic processes. An anaerobic process is a process that uses metabolism without air, while an aerobic process is a process that uses metabolism with air.

Synopsis of Cellular Respiration

            In Cellular Respiration, energy in organic compounds, including glucose, is harnessed. In stage one of Cellular Respiration, glucose is broken down in the cytoplasm through glycolysis, and converted to pyruvate, which produces a small amount of ATP and NADH. Aerobic and anaerobic processes both undergo glycolysis. In an aerobic process of cellular respiration, Stage 2 is when pyruvate and NADH are used to make ATP but in an anaerobic process of cellular respiration, a pyruvate is converted to either ethanol and carbon dioxide or lactate through fermentation.

            Cellular Respiration can be summarized further with its chemical equation:

The equation means that glucose, oxygen, and enzymes are needed to form carbon dioxide, water, and energy in the form of ATP. In addition, the numbers mean that the complete breakdown of a glucose molecule require six oxygen molecules and forms six carbon dioxide molecules, six water molecules, and ATP.

CHEMICAL EQUATION FOR CELLULAR RESPIRATION: WHAT IT REPRESENTS

      Glucose = required to start glycolysis
Oxygen = Needed for Glycolysis to move through the Krebs cycle, otherwise go through fermentation
Carbon dioxide = Released from six-carbon compound in Krebs cycle
Water = Created in electron transport chain when hydrogen ions, oxygen, and electrons combine
ATP = Created in electron transport chain when hydrogen ions diffuse into the inner compartment of the electron transport chain through a channel protein

Stages of Cellular Respiration in more detail
Stage 1
Stage 2 (aerobic)
Stage 3 (aerobic)
Stage 2 (anaerobic)

Stage 1:

            In Stage 1 of Cellular Respiration, Glycolysis occurs, where glucose is broken down in the cytoplasm. Both anaerobic and aerobic processes go though glycolysis. During glycolysis, a one six-carbon molecule of glucose is broken down to three-carbon pyruvates with the help of enzymes. Pyruvate is an ion, a molecule that has lost or gained one or more electrons. This ion makes up a three-carbon organic acid called pyruvic acid. Even after glycolysis, the pyruvate contains energy that was once stored in the six-carbon compound, the glucose molecule. If hydrogen atoms are transferred to NAD+, an electron acceptor, NADH is produced. NADH helps during glycolysis, because NADH donates electrons to other organic compounds. Because of that, NAD+ is reproduced, which can then accept more electrons. Aside from pyruvates being produced during glycolysis, 4 ATP molecules are also produced. Glycolysis requires 2 ATP molecules for energy, but gains two molecules, making 4 in total, with a total gain of two.

Roles in Stage 1

Glycolysis = enzyme-assisted process that breaks down a glucose molecule to two three-carbon pyruvates
Pyruvate = ion produced during glycolysis
2 ATP = help give energy to start glycolysis
NADH = helps glycolysis by donating electrons to other organic compounds, making NAD+ reproducible
NAD+ = electron acceptor

Stage 2 Aerobic Respiration

            During aerobic cellular respiration, the pyruvate produced during glycolysis enters a mitochondrion where it is converted to a two-carbon compound, making a reaction. A Carbon dioxide molecule, a NADH molecule, and a two-carbon acetyl group are produced because of this reaction. The two-carbon acetyl group gets attached to coenzyme A, a molecule, which forms acetyl-CoA, a compound.

            The Krebs cycle is a series of enzyme-assisted reactions, through which Acetyl-CoA enters. First, a four-carbon compound merges with Acetyl-CoA, which turns into a six-carbon compound releasing coenzyme A. Then, after Carbon dioxide is released from the six-carbon compound, a five-carbon compound is formed. More NADH is produced when NAD+ accepts more electrons. A four-carbon compound is produced after carbon dioxide is released from the five-carbon compound. A molecule of both ATP and NADH are produced. Next, a four-carbon compound gets converted to a new four-carbon compound. FAD, an electron acceptor, gets electrons transferred to it, making a molecule of FADH2, another type of electron carrier. Finally, the new four-carbon compound gets converted to another four-carbon compound, and can restart the cycle after acetyl-CoA enters again. Another molecule of NADH is also produced. Because of the Krebs cycle, NADH and FADH2 is produced, which both contain most of the energy that used to be stored in pyruvate and glucose.

Roles in Stage 2:

Krebs Cycle = series of enzyme-assisted reactions, process that produces NADH and FADH2
FADH2 = another type of electron carrier produced when electrons are transferred to FAD
FAD = electron acceptor

Stage 3 Aerobic Respiration

            After stage 2 of aerobic cellular respiration, NADH and FADH2 produced by the Krebs Cycle go through an electron transport chain. The electron transport chain takes place in the inner membranes of mitochondria and is used to pump hydrogen ions out of the inner mitochondrial compartment. Because hydrogen ions accumulate in the outer compartment of this mitochondrian compartment, a concentration gradient is produced. A carrier protein help the hydrogen ions to diffuse back into the inner compartment. This carrier protein also produces ATP after a phosphate group is added to ADP. Hydrogen ions and electrons combine with oxygen molecules to form water molecules. Finally, ATP is produced after the hydrogen ions diffuse into the inner compartment through a channel protein.

Roles in Stage 3

Electron transport chain = chain that takes place in the inner membranes of mitochondria that are used to pump hydrogen ions out of the inner mitochondrial compartment
ATP = produced after hydrogen ions diffuse into the inner compartment of the electron transport chain through an inner compartment

Diagram: 
             Hydrogen Ions: Accumulate in outer compartment of mitochondria, producing concentration gradient
             ATP Producing Carrier Protein: Helps hydrogen ions to diffuse back inside the mitochondria compartment; also produces ATP when a phosphate group is added to ADP
             Oxygen Molecules: Combines with electrons and hydrogen ions to form water molecules
             ATP: Produced when hydrogen ions diffuse back into the inner compartment of the mitochondria through a channel protein

 

Stage 2 Anaerobic Respiration:

            During Stage 2 of anaerobic respiration, fermentation occurs after glycolysis. This process recycles NAD+ necessary to continue making ATP through glycolysis. There are literally a dozen different kinds of fermentation, but two very important types of fermentation are lactic acid fermentation and alcoholic fermentation.

Lactic Acid Fermentation

            During Lactic acid fermentation Lactate, an ion of lactic acid, is produced. Lactate is produced after a three-carbon pyruvate is converted to a three-carbon lactate through fermentation. Lactate acid fermentation occurs in some organisms.

Alcoholic Fermentation

            During alcoholic fermentation, Ethanol, a two-carbon compound is produced. During this form of fermentation, pyruvate is first converted to a two-carbon compound, releasing carbon dioxide. Then, electrons are transferred from a molecule of NADH to a two-carbon compound, ethanol.

Terms to Know

Cellular Respiration = process where heterotrophs harvest the energy in food molecules
Heterotrophs = humans and other animals that get their energy by undergoing cellular respiration
Anaerobic Processes = processes that uses metabolism without air
Aerobic Processes = processes that use metabolism with air
Metabolism = sum of all the chemical reactions carried out in a chemical equation
ATP = organic molecule that acts as the main energy source of cells; adenosine triphosphate; has three phosphate groups, a base (adenine) and a sugar (ribose)
Glycolysis = process that breaks down a molecule of glucose to two three-carbon pyruvates
Pyruvate = Ion (molecule that has lost or gained one or more electrons) of a three-carbon organic acid called pyruvic acid
NADH = electron carrier
Fermentation = recycling of NAD+ to continue anaerobic glycolysis
NAD+ = electron acceptor
mitochondria = organelle that makes ATP
Krebs Cycle = series of enzyme-assisted reactions
FAD = electron acceptor
FADH2 = electron carrier
Electron transport chain = chain that takes place in the inner membranes of mitochondria that are used to pump hydrogen ions out of the inner mitochondrial compartment
Lactic Acid Fermentation = Fermentation that produces Lactate
Alcoholic Fermentation = Fermentation that produces Ethanol


Heterotrophs


Oxygen


Glucose


Hydrogen


NAD+


NADPH

 

 

 

 

 

 

 


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