Sapna Gupta, Associate Professor
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CH317/Fall 2006

Organic Chemistry I

MWF 10:00 - 10:50am

Room 317

Text Organic Chemistry L. G. Wade
Highly Recommended: Organic Chemistry as a Second Language, Dr. David R. Klein,
(ISBN: 0-471-27235-3)

Course Description

An introduction to the chemistry of carbon based compounds. Nomenclature, structure, bonding, and reaction mechanisms of organic importance in pharmaceutics. Prerequisite: CH108 and CH108L. Corequisite: CH 317L. 3:0:3

Course Objectives

On completion of this course the student should:

  • Describe hybridization, orbitals, resonance, hydrogen bonding, polarity, homologous series, functional groups, aromaticity, intermolecular forces,
  • writing organic structures
  • Know nomenclature, structure, physical properties, synthesis, and reactions of alkenes, alkynes, alcohols, ethers, epoxides, sulfides
  • Stereochemistry
  • Describe nucleophilic substitution and elimination reactions and the kinetics behind these
  • Describe conjugated systems
  • Principles of acidity and basicity and reaction mechanisms
  • Carry out simple organic synthesis

Classroom Conduct

  1. There will be no drinking or eating in the classroom, unless approved by the instructor.
  2. All assignments submitted should be stapled, neat and legible.
  3. Any report submitted should be printed using a printer that has black ink. Colored reports will not be accepted unless the color is on a graph or picture.
  4. Tardiness in coming to class, late submission of homework and quizzes will constitute in a loss of class participation points.
  5. Rude behaviour towards the instructor or a colleague will not be tolerated.
  6. Students should avail all opportunities to participate in class, a disinterest in class participation will lead to loss of class participation points
  7. You are advised to do the following: 
  • Devote at least an hour daily to revise class notes and read ahead of time. 
  • To solve problems assigned in the syllabus as the course continues. It is your responsibility to keep solving these problems as the course progresses. These problems will help you understand the subject better and also give you insight on what is expected of you in exams.
  • to keep exam days free of any other commitment as there will be absolutely no makeup exams or quizzes. Exam dates have been set in the syllabus, unless an absolute emergency arises (from the instructors point of view) none of those dates will be changed.
  • Generally there will be a review session before each exam. You are encouraged to bring you problems to these sessions and clarify any doubts. The day the exam is handed back, the common problems in the exam will be discussed, please make sure you attend these important sessions. Students should without hesitation request for study sessions at any time and they will be scheduled according to time available.

Late Submission of Course Materials

Class quizzes and exams cannot be made up. Homework and internet quizzes are to submitted on the dates given during class. 20% of the score will be deducted for each day the assignment is submitted late. Assignments submitted after one week will not be accepted for grading.


Grading scale

A 85 and above
B 75-84
C 60-74
D 50-59
F 49 and below

Exams

45% 3 mid term exams 
(15% each)
Sept. 22, Oct. 13 and Nov. 17 (all on Fridays); each exam will be one hour long, not comprehensive
25% Final exam Dec 13,  10:15 - 12:15 pm 2 hours long and comprehensive
10% Quizzes You may expect a 5 min quiz in every class. In addition there will weekly quizzes, which will be 10-15 mins long. All these collectively make up the 10%.
15% Homework will be assigned in the class throughout the semester
5% Class participation  attendance, participation in the class and general etiquette

Please note: You will be informed ahead of time any changes made in the above schedules. Unexcused absence of 6 lectures will result in a F in the class


Topics to be Covered

Chapter Topics Assignment
Chapter 1
General Introduction
(sections 1.1 - 1.9)

Introduction to organic chemistry, bonding (orbitals and hybridization), resonance

Practice: 1, 2, 3, 5, 8, 36, 41
Submit: 20, 23, 25, 35, 37, 40
due 1st Sept
Chapter 2 and Chapter 1
Introduction to Organic Molecule
Hybridization and organic chemistry, hdyrogen bonding, polarity, homologous series, functional groups, aromaticity, intermolecular forces, writing organic structures (chapter 1 section 1.10 -1.11) Practice:
Chapter 1: 9, 10, 11
Chapter 2: 3, 4, 5, 8, 10, 11, 17, 18, 19, 20, 21, 22,
Submit:
Chapter 1: 26, 27, 28, 29,
Chapter 2: 25, 26, 33, 34, 35, 36, 38, 39, 40, 41, 42, 44
due 20th Sept
Chapter 3
Structure and Stereochemisty of Alkanes
nomenclature, isomers, physical properties, cycloalkanes, conformational analysis Practice: 2 � 10, 14 � 17, 19, 25, 27,
Submit: 33, 34, 35, 36, 37, 38, 40, 42, 44
Chapters 4
The Study of Chemical Reactions
Types of reactions, radical reactions 41, 43, 48
Chapter 5
Stereochemistry
chirality, nomenclature, optical activity, optical isomers, enantiomers, racemic mixtures, diasteriomers, meso compounds, absolute configuration, resolution Practice: 5,6,11,14,15,16,1719
Submit: 25c,e,g,h,i,k,n,p,r, 26, 28, 29, 30, 31
due 3rd Nov - please remember to write the questions with answers.
Chapter 6
Alkyl Halides: Nucleophilic Substitution and Elimination
Acidity and basicity (section 1.12-1.14), alkyl halides, nucleophilic substitution and elimination reactions; kinetics of reaction, SN2, SN1, E1 and E2 reactions, stereochemistry of substitution and elimination reactions Practice: 3, 14,15,16,19,21,23,26, 27,40
Submit:43, 44, 46, 47, 50, 53, 55, 56, 60, 66. Extra credit - 75
due 16 Nov
Chapters 7 and 8
Alkenes:synthesis and reactions
 nomenclature, synthesis and reactions Chapter 7:
Practice: 5,6,7,8,13,19,25,28,
Submit: 31, 32, 33, 34, 36, 38, 40, 41, 42, 43, 44, 45
due 1st Dec
Chapter 8:
Practice: 1, 4, 5, 6,11, 23, 28,29, 34, 37, 50, 61 63,
Submit: 47, 48, 49, 58, 59, 60, Extra credit: 64
due 11th Dec - 11am
Chapter 9
Alkynes
nomenclature, synthesis and reactions Submit: 27, 29, 30, 33, 34, 36abf38
due 11th Dec
Chapters 10 and 11
Alcohols: synthesis and reactions
Nomenclature, synthesis and reactions of alcohols, Grignard reagents
Chapter 14
Ethers, Epoxides and Sulfides
nomenclature, synthesis and reactions
Chapter 15
Conjugated systems
dienes, resonance, conjugation, Diels-Alder reaction (15.13 UV to be done in CH318)
  Additional aspects: environmental issues, medical importance, biochemical molecules, polymers etc  

Links

Quizzes:

Review and Notes on the Internet:

Molecules:


Model Sets

Hints on buying a model set:

1) buy it only if you really think you need it.
2) you can get a larger kit and share with a friend.
3) you may not need a model set if you are not going to be a chemistry major
4) make sure you see (even if its a picture) the model set before you buy it.
5) try not to buy a model that will break away eg the with wooden pieces.
6) if you are planning to take more chemistry/biology courses, buy a kit that can be used for both organic and inorganic chemistry
7) you can always sell your model kit next year if you think you will not need it.

Here are some places to start looking

1) MolyMod: http://www.molymod.com/

2) Darling Models: http://www.darlingmodels.com/ccp51/cgi-bin/cp-app.cgi not the best kind, hard to rotate bonds.

3) Another Place to get MolyMod models: http://www.indigo.com/models/molymod-molecular-model-sets.html (62009 is the best one to buy)

4) Prentice Hall Model Set: this is the most professional one.
http://www.amazon.com/exec/obidos/tg/detail/-/0205081363/102-9171052-0038565?v=glance
http://www.prenhall.com/list_ac/searches/MC0511.html

5) UMKC bookstore sells model sets, you may want to take a look there also, if its convenient for you.

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