> Scientific publications

Years: 1998 - 1999 - 2000 - 2001 - 2002 - 2003 - 2004 - 2005 - 2006 - 2007- 2008- 2009

2009

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Persichetti, E., Chuzhanova, N.A., Dardis, A., Tappino, B., Pohl, S., Thomas, N.ST., Rosano, C., Balducci, C., Paciotti, S., Dominissini, S., Montalvo, A.L., Sibilio, M., Parini, R., Rigoldi, M., Di Rocco, M., Parenti, G., Orlacchio, A., Bembi, B., Cooper, D.N. and Filocamo, M., Beccari, T.
Identification and Molecular Characterization of Six Novel Mutations in the UDP-N-Acetylglucosamine-1-Phosphotransferase Gamma Subunit (GNPTG) Gene in Patients with Mucolipidosis III Gamma (2009) Human Mutation 30(6):978-984

Lanciotti, M., Caridi, G., Rosano, C. , Pigullo, S., Lanza, T., Dufour, C.
Severe congenital neutropenia: a negative synergistic effect of multiple mutations of ELANE (ELA2) gene (2009) Br J Haematol., Epub ahead of print

Zanetti, A., Ferraresi, E., Picci, L., Filocamo, M., Parini, R., Rosano, C., Tomanin, R. and Scarpa, M.
Segregation analysis in a family at risk for Maroteaux-Lamy syndrome conclusively reveals c.1151G>A (p.S384N) as to be a polymorphism (2009) European Journal of Human Genetics Epub ahead of print

Brookes, E., Demeler, B., Rosano, C., Rocco, M.
The implementation of SOMO (SOlution MOdeller) in the UltraScan analytical ultracentrifugation data analysis suite: enhanced capabilities allow the reliable hydrodynamic modeling of virtually any kind of biomacromolecule. (2009) European Biophysics Journal Epub ahead of print

Fancello, T., Dardis, A., Rosano, C., Tarugi, P., Tappino, B., Zampieri, S., Pinotti, E., Corsolini, F., Fecarotta, S., D'Amico, A., Di Rocco, M., Uziel, G., Calandra, S., Bembi, B., Filocamo, M.
Molecular Analysis of NPC1 and NPC2 Gene in Thirty-Four Niemann-Pick C Italian Patients: Identification and Structural Modelling of novel mutations (2009) Neurogenetics 10(3):229-239

Lappano, R., Rosano, C., Plastina, P.L., Bartolo, G., Albanito, L., Madeo, A., Forti, L., Stivala, L.A., Iacopetta, D., Dolce, V., Pezzi, V., Maggiolini, M.
Structure-activity relationships for binding of resveratrol and four analogues to estrogen receptor alpha in breast cancer cells (2009) Molecular Nutrituion and Food Research53(7):845-858

Cesarini, S., Spallarossa, A., Ranise, A., Schenone, S., Rosano, C.,, La Colla, P., Sanna, G., Busonera, B., Loddo, R.
N-acylated and N,N'-diacylated imidazolidine-2-thione derivatives and N,N'-diacylated tetrahydropyrimidine-2(1H)-thione analogues: synthesis and antiproliferative activity. (2009) European Journal of Medicinal Chemistry 44: 1106-18.

2008

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Pittis, M.G., Donnarumma, M., Montalvo, A.L.E., Dominissini, S., Kroos, M., Rosano, C., Stroppiano, M., Bianco, M.G., Donati, M.A. Parenti, G., Ciana, G., Di Rocco, M., Reuser, A., Bembi, B., Filocamo, M.
Molecular and functional characterization of eight novel GAA mutations in Italian Infants with Pompe disease (2008) Human Mutation, 29:E27-36

Rocco, M., Rosano, C., Weisel, J.W., Horita, D.A., Hantgan, R.R.
Integrin conformational regulation: uncoupling extension/tail separation from changes in the head region by a multi-resolution approach (2008) Structure, 16: 954-964

Pierotti, M.A., Lombardo, C., Rosano, C.
Nanotechnology: going small for a giant leap in cancer diagnostic and therapeutics (2008) Tumori, 94:191-196

2007

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Gnemmi, I., Scotti, C., Cappelletti, D., Canonico, P.L., Condorelli, F., Rosano, C.
Expression, purification and preliminary crystallographic studies on the catalytic region of the non-receptor tyrosine kinase Fes (2007) Acta Crystallogr. sec. F, 63, 18-20

2006

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Corazza, A., Rosano, C., Pagano, K., Alverdi, V., Esposito, G., Capanni, C., Bemporad, F., Plakoutsi, G., Stefani, M., Chiti, F., Zuccotti, S., Bolognesi, M., Viglino, P.
Structure, conformational stability and enzymatic properties of acylphosphatase from the hyperthermophile Sulfolobus solfataricus (2006) Proteins: Structure, Functions and Bioinformatics,62, 64-79

Bicocchi, M.P., Pasino, M., Rosano, C., Molinari, A.M., Della Valle, E., Lanza, T., Bottini, F., Acquila, M.
Insight into molecular changes of the F IX protein in 21 patients with Haemophilia B (2006) Haemophilia 12, 263-270

2005

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Rosano, C., Zuccotti, S., Bolognesi, M.
The three-dimensional structure of ß2 microglobulin: results from X-ray crystallography (2005) BBA - Proteins and Proteomics Review article, 1753, 85-91

Zuccotti, S., Rosano, C., Bemporad, F., Stefani, M., Bolognesi, M.
Preliminary characterization of two different crystal forms of acylphosphatase from the hyperthermophile archaeon Sulfolobus solfataricus (2005) Acta Crystallogr. sec. F 61, 144-146.

Bicocchi, M.P., Pasino, M., Lanza, T., Bottini, F., Molinari, A.C., Caprino, D., Rosano, C., Acquila, M.
Small FVIII gene rearrangements in 18 Hemophilia A patients: five novel mutations. (2005) Am. J. Hemat.,78, 117-122

Bicocchi, M.P., Pasino, M., Lanza, T., Bottini, F., Molinari, A.C., Rosano, C., Acquila, M.
Ectopic mRNA analysis and molecular modelling substantiate severe haemophilia in a patient with a FVIII gene splice mutation. (2005) Thromb. Haemostasis, 93, 391-2

2004

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Rosano, C., Zuccotti, S., Cobucci-Ponzano,B., Mazzone, M.L., Rossi, M., Moracci, M., Petoukhow, M.V., Svergun, D.I., Bolognesi, M.
Structural charactrerization of the nonameric assembly of an Archaeal alpha-L-fucosidase by synchrotron small angle X-ray scattering. (2004) Biochem. Biophys. Res. Comm., 320/1, 176-182
Pubmed

Zuccotti, S., Rosano, C.,Ramazzotti, M., Degl'Innocenti, D., Stefani, M., Manao, G., Bolognesi, M.
3D-structural characterization of a novel Drosphila melanogaster Acylphosphatase. (2004) Acta Crystallogr. sec.D, 60, 1177-1179
Pubmed

Relini, A., Torassa, S., Rolandi, R., Gliozzi, A., Rosano, C., Canale, C., Bolognesi, M., Plakoutsi, G., Bucciantini, M., Chiti, F., Stefani, M.
Monitoring the process of HypF fibrilization and liposome permeabilization by protofibrils. (2004), J.Mol.Biol., 338, 943 - 957
Pubmed

Rosano, C., Zuccotti, S., Mangione, P., Giorgetti,S., Bellotti, V., Pettirossi, F., Corazza, A., Viglino, P., Esposito, G., Bolognesi, M.
ß2 microglobulin H31Y variant 3D-structure highlights the protein natural propensity towards intermolecular aggregation. (2004), J.Mol. Biol., 335, 1051 - 1064
Pubmed

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S.Zuccotti, C.Rosano, P.Mangione, V.Bellotti, M.Bolognesi
Preliminary crystallographic characterization of human ß2 microglobulin His31Tyr mutant in a tetrameric assembly (2003). Acta Crystallogr. sec. D, 59, 1270-1272
Pubmed

M.P.Bicocchi, M.Pasino, T.Lanza, F.Bottini, P.G.Mori, A.C.Molinari, C.Rosano, M.Acquila
Analysis of eighteen novel mutations in the factor VIII gene (2003) Brit.J. Haematol. , 122, 810-817
Pubmed

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C.Rosano, S.Zuccotti, M.Stefani, M. Bucciantini, G.Ramponi, M.Bolognesi
Crystallization and preliminary X-ray characterization of the acylphosphatase-like domain from the E.coli hydrogenase maturation factor HypF. (2002). Acta D, 58, 524-525
Pubmed

C.Rosano, S.Zuccotti, M.Stefani, M. Bucciantini, G.Ramponi, M.Bolognesi
Crystal Structure and Anion Binding in the Prokaryotic Hydrogenase Maturation Factor HypF Acylphosphatase-like Domain (2002) J.Mol.Biol., 321, 785-796
Pubmed

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M. E. Stroppolo, A. Pesce, M. D'Orazio, D. Bordo, C. Rosano, M. Milani, A. Battistoni, M. Bolognesi, A. Desideri
Single mutations at the subunit interface modulate copper reactivity in Photobacterium leiognathi Cu,Zn superoxide dismutase. (2001) J.Mol.Biol. , 308, 555-563.
Pubmed

S.Zuccotti, D.Zanardi, C.Rosano, L.Sturla, M.Tonetti, M.Bolognesi
Kinetic and crystallographic analyses suggest a sequential ordered bi bi mechanism for E.coli Thymidylyltransferase. (2001) J.Mol.Biol., 313, 831-843.
Pubmed

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C. Rosano, G. Izzo, L. Sturla, A. Bisso, M. Tonetti, M. Bolognesi. The high resolution structure of GDP 4-keto-6-deoxy-D-mannose epimerase/reductase. (2000) Croatica Chemica Acta, 73, 887-899.

S. Bruno, S. Bettati, A. Mozzarelli, M. Bolognesi, C. Rosano, D. Deriu, A. Tsuneshige, T. Yonetani, R. Henry. Oxigen Binding by (Fe2+)2(Ni2+)2 Hb Crystals (2000) Protein Science, 9, 683-692.
Pubmed

C. Rosano, A. Bisso, G. Izzo, M. Tonetti, L. Sturla, A. DeFlora, M. Bolognesi. Probing the catalytic mechanism of GDP 4-keto-6-deoxy-D-mannose epimerase/reductase by kinetic and crystallographic characterization of site-specific mutants (2000) J. Mol. Biol., 303 (1), 77-91.
Pubmed

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C. Rosano, P. Arosio, M. Bolognesi. X-Ray structure of Avidin. (1999) Rewiev Article. Genetic Analysis: Biomolecular Engineering, 16, pp5-12
Pubmed

D. Bordo, D. Matak, C. Djinovic-Carugo, C. Rosano A. Pesce, M. Bolognesi, M. E. Stroppolo, M. Falconi, A. Battistoni, A. Desideri. Evolutionary constrains for dimer formation in prokaryotic Cu,Zn Superoxide Dismutase (1999) J. Mol. Biol., 285, (1), 283-296.
Pubmed

M. Bolognesi, C. Rosano, A. Borassi, R. Losso, M. Rizzi, A. Mozzarelli, J. B. Wittenberg, A. Boffi, P. Ascenzi. Structural Bases for cyanide binding to Lucina pectinata monomeric Hemoglobin I and to Sperm Whale Myoglobin. A X-Ray crystallographic study. (1999) Biophys. J. 77, 1093-1099  
Pubmed

C. Rosano, E. Sabini, G. Murshudov, D. Deriu, M. Rizzi, M. Bianchi, G. Serafini, M. Magnani, M. Bolognesi. Binding of non-catalytic ATP to Human Hexokinase type I highlights the structural components for enzyme:membrane association control. (1999) Structure, 7, 1427-37.
Pubmed

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E. Sabini, C. Rosano, C. Capasso, M. Rizzi, M. Bolognesi, M. Bianchi, G. Serafini, E. Bartolucci, M. Magnani. Expression, purification and preliminary studies of human hexokinase type I. (1998) Protein and Peptide Letters, vol. 5, n. 4 pp 237-242

E. Nardone, C. Rosano, P. Santambrogio, F. Curnis, A. Corti, F. Magni, A. G. Siccardi, G. Paganelli, R. Losso, B. Apreda, M. Bolognesi, A. Sidoli, P. Arosio. Biochemical characterization and crystal structure of a recombinant hen avidin and its acidic mutant expressed in Escherichia coli . (1998) Eur.J.Biochem., 256, 453-460.
Pubmed