Get your own Free Home PageLyme disease is a serious bacterial infection caused by a tick bite and affects humans and animals.
This page contains citations and complete abstracts for medical and scientific articles from the National Institutes of Health (NIH), National Library of Medicine (NLM) MEDLINE database about pregnancy complications and Lyme disease. Citations are sorted by date within categories with particularly significant portions highlighted in bold red lettering.
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TITLE:
Lyme borreliosis as a cause of facial palsy during pregnancy.
AUTHORS:
Grandsaerd MG; Meulenbroeks AA
AUTHOR AFFILIATION:
Department of Otorhinolaryngology, Rijnstate hospital Wagnerlaan 55
6815 AD, Arnhem, The Netherlands
ABSTRACT:
The medical history of a pregnant woman in whom the initial pattern of
complaints suggested hyperemesis gravidarum is described. After about
18 days the patient developed left facial palsy. Repeated tests
eventually confirmed the diagnosis of neuroborreliosis.
The problems
concerning diagnostics, therapy and the possible complications of
Lyme borreliosis during gestation are described.
NLM PUBMED CIT. ID: 10817889 NLM CIT. ID: No Cit. ID Assigned
SOURCE:
Eur J Obstet Gynecol Reprod Biol 2000 Jul 1;91(1):99-101
TITLE:
Maternal Lyme disease and congenital malformations: a cord blood serosurvey in endemic and control areas.
AUTHORS:
Williams CL; Strobino B; Weinstein A; Spierling P; Medici F
AUTHOR AFFILIATION:
Child Health Center, American Health Foundation, Valhalla, New York
10595, USA.
ABSTRACT:
This report describes a cohort study of over 5000 infants and their
mothers who participated in a cord blood serosurvey designed to
examine the relationship between maternal exposure to Lyme disease
and adverse pregnancy outcome.
Based on serology and reported
clinical history, mothers of infants in an endemic hospital cohort
are 5 to 20 times more likely to have been exposed to B. burgdorferi
as compared with mothers of infants in a control hospital cohort. The
incidence of total congenital malformations was not significantly
different in the endemic cohort compared with the control cohort, but
the rate of cardiac malformations was significantly higher in the
endemic cohort [odds ratio (OR) 2.40; 95% confidence interval (CI)
1.25, 4.59]
and the frequencies of certain minor malformations
(haemangiomas, polydactyly, and hydrocele), were significantly
increased in the control group. Demographic variations could only
account for differences in the frequency of polydactyly. Within the
endemic cohort, there were no differences in the rate of major or
minor malformations or mean birthweight by category of possible
maternal exposure to Lyme disease or cord blood serology. The
disparity between observations at the population and individual
levels requires further investigation. The absence of association at
the individual level in the endemic area could be because of the
small number of women who were actually exposed either in terms of
serology or clinical history. The reason for the findings at the
population level is not known but could be because of artifact or
population differences.
NLM PUBMED CIT. ID: 7479280 NLM CIT. ID: 96061203
SOURCE:
Paediatr Perinat Epidemiol 1995 Jul;9(3):320-30
TITLE:
[Manifestation of Lyme arthritis in the puerperal period]
VERNACULAR TITLE:
Manifestation einer Lyme-Arthritis im Wochenbett.
AUTHORS:
Bussen S; Steck T
AUTHOR AFFILIATION:
Universitatsfrauenklinik Wurzburg.
ABSTRACT:
Lyme disease, a tick-transmitted spirochetal illness caused by
Borrelia burgdorferi, usually begins with a characteristic erythema
chronicum migrans accompanied by flu-like symptoms. This phase may
later be followed by meningitis, neuritis, carditis or arthritis.
Congenital abnormalities due to maternal infection during pregnancy
have been described.
We report on a case of a 36-year old V gravida
III para. After a normal pregnancy and a Cesarean section the patient
developed postpartal an acute Lyme arthritis.
NLM PUBMED CIT. ID: 7975802 NLM CIT. ID: 95066274
SOURCE:
Z Geburtshilfe Perinatol 1994 Aug;198(4):150-2
TITLE:
Congenital infections and the nervous system.
AUTHORS:
Bale JF Jr; Murph JR
AUTHOR AFFILIATION:
Department of Pediatrics, University of Iowa College of Medicine, Iowa
City.
ABSTRACT:
Despite vaccines, new antimicrobials, and improved hygienic practices,
congenital infections remain an important cause of death and
long-term neurologic morbidity among infants world-wide. Important
agents include Toxoplasma gondii, cytomegalovirus, Treponema
pallidum, herpes simplex virus types 1 and 2, and rubella virus. In
addition,
several other agents, such as the varicella zoster virus,
human parvovirus B19, and Borrelia burgdorferi, can potentially
infect the fetus and cause adverse fetal outcomes.
This article
provides an overview of these infectious disorders and outlines
current strategies for acute treatment and long-term management.
NLM PUBMED CIT. ID: 1321971 NLM CIT. ID: 92342460
SOURCE:
Pediatr Clin North Am 1992 Aug;39(4):669-90
TITLE:
[Borrelia infections from a dermatological viewpoint]
VERNACULAR TITLE:
Borrelieninfektion aus dermatologischer Sicht.
AUTHORS:
Vocks E; Engst R; Borelli S
AUTHOR AFFILIATION:
Dermatologische Klinik und Poliklinik Technischen Universitat Munchen.
ABSTRACT:
Erythema migrans (EM), Borrelia lymphocytoma (BL) and acrodermatitis
chronica atrophicans (ACA) are the established dermatological
manifestations of borrelia infection, a complex multiorganic disease.
Analogous to syphilis Borrelia infection can be classified by three
stages, at which stage I (localized infection) and II (disseminated
infection) are manifestations of early infection and stage III
(persistent infection) a symptom of late infection. At all stages
skin manifestations can be present, the above mentioned as
stage-marker as well as other non-specific polymorphous skin lesions
which sometimes appear at stage II. Because of its frequent (60-80%)
occurrence in all borrelia infections EM has a pathognomonic
importance for borrelia infection. In diagnosis serology is currently
the only practical laboratory aid. False negative and false positive
results must be considered. Treatment of choice is ceftriaxone,
penicillin G (or amoxycillin) or tetracycline. Prophylactic
antibiotic therapy for tick bites is not recommended.
Congenital
borrelia infections seem to be unusual, but it is likely that they
can occur and cause different adverse fetal outcome or abortion.
NLM PUBMED CIT. ID: 1922122 NLM CIT. ID: 92017931
SOURCE:
Monatsschr Kinderheilkd 1991 Jul;139(7):425-8
TITLE:
Lyme disease during pregnancy.
AUTHORS:
Schutzer SE; Janniger CK; Schwartz RA
AUTHOR AFFILIATION:
Department of Allergy and Immunology, New Jersey Medical School,
Newark 07103-2714.
ABSTRACT:
Lyme disease, caused by infection with Borrelia burgdorferi, can
affect those exposed to a vector tick. Pregnant women are no
exception, and such infection places the fetus at risk.
It is
particularly important to recognize the disease early so that
effective therapy may be instituted. Although the present patient had
a favorable outcome, not all do. Clinical diagnosis is especially
important since conventional laboratory tests may be inadequate or
require lengthy periods of time before a positive result occurs. The
dermatologic sign of Lyme disease, erythema migrans, although
occurring in only 50 percent of cases, is likely to be the most
important diagnostic sign.
NLM PUBMED CIT. ID: 2070648 NLM CIT. ID: 91300895
SOURCE:
Cutis 1991 Apr;47(4):267-8
TITLE:
Gestational Lyme borreliosis. Implications for the fetus.
AUTHORS:
MacDonald AB
AUTHOR AFFILIATION:
Southampton Hospital, New York.
ABSTRACT:
Great diversity of clinical expression of signs and symptoms of
gestational Lyme borreliosis parallels the diversity of prenatal
syphilis. It is documented that transplacental transmission of the
spirochete from mother to fetus is possible.
Further research is
necessary to investigate possible teratogenic effects that might
occur if the spirochete reaches the fetus during the period of
organogenesis.
Autopsy and clinical studies have associated
gestational Lyme borreliosis with various medical problems including
fetal death, hydrocephalus, cardiovascular anomalies, neonatal
respiratory distress, hyperbilirubinemia, intrauterine growth
retardation, cortical blindness, sudden infant death syndrome, and
maternal toxemia of pregnancy.
Whether any or all of these
associations are coincidentally or causally related remains to be
clarified by further investigation.
It is my expectation that the
spectrum of gestational Lyme borreliosis will expand into many of the
clinical domains of prenatal syphilis.
NLM PUBMED CIT. ID: 2685924 NLM CIT. ID: 90069113
SOURCE:
Rheum Dis Clin North Am 1989 Nov;15(4):657-77
TITLE:
[Clinical aspects of Borrelia burgdorferi infections]
VERNACULAR TITLE:
Klinische Aspekte der Borrelia-burgdorferi-Infektionen.
AUTHORS:
Neubert U
AUTHOR AFFILIATION:
Dermatologische Klinik der Ludwig-Maximilians-Universitat Munchen.
ABSTRACT:
Skin lesions due to Borrelia burgdorferi-like erythema migrans,
lymphadenosis cutis benigna, and acrodermatitis chronica atrophicans
- are hall-marks of a systemic infection, which tends to a
chronically relapsing course. Even if the skin lesions are missing,
or disappear spontaneously, the infection may persist and affect
other organs. This presumption is supported by the outcome of a
long-term follow-up study on seropositive forest workers. In
association with meningopolyneuritis (Garin-Bujadoux-Bannwarth
disease) and acrodermatitis chronica atrophicans - myositis and
fasciitis have been recently reported as further possible
manifestations of Borrelia burgdorferi infection.
Borrelial infection
during pregnancy should promptly be treated with antibiotics in high
dosages, in order to prevent maternal-fetal transmission of borrelial
organisms resulting in stillbirth or congenital defects of the
newborn.
NLM PUBMED CIT. ID: 2678790 NLM CIT. ID: 90021654
SOURCE:
Z Hautkr 1989 Aug 15;64(8):649-52, 655-6
TITLE:
Infants born to mothers with antibodies against Borrelia burgdorferi at delivery.
AUTHORS:
Nadal D; Hunziker UA; Bucher HU; Hitzig WH; Duc G
AUTHOR AFFILIATION:
Abteilungen fur Infektionskrankheiten und Immunologie der Universitat,
Zurich, Switzerland.
ABSTRACT:
A serological survey over a 1-year period of 1416 mothers at delivery
and their 1434 offspring for the presence of anti-Borrelia
burgdorferi antibodies revealed a prevalence of 0.85%.
Clinically
active Lyme disease during pregnancy was found in 1 of these 12 women
with elevated titres and the child was born with a ventricular septal
defect. Of six affected children, two had hyperbilirubinaemia, one
muscular hypotonia, one was underweight for gestational age, one was
macrocephalic, and one had supraventricular extrasystoles. Anomalous
findings could not be attributed to B. burgdorferi due to a lack of
serological evidence of intrauterine infection. Our data do not imply
the need for serological screening in pregnancy, however, the
importance of recognition and treatment of Lyme disease in pregnancy
is emphasized.
NLM PUBMED CIT. ID: 2920747 NLM CIT. ID: 89153177
SOURCE:
Eur J Pediatr 1989 Feb;148(5):426-7
TITLE:
Lyme Borrelia positive serology associated with spontaneous abortion in an endemic Italian area.
AUTHORS:
Carlomagno G; Luksa V; Candussi G; Rizzi GM; Trevisan G
AUTHOR AFFILIATION:
Dept. of Obstetrics and Gynecology, University of Trieste School of
Medicine.
ABSTRACT:
Lyme borreliosis acquired during pregnancy may be associated with
stillbirth and fetal malformations. This paper reports preliminary
results of a study intended to evaluate the frequency of Borrelia
burgdorferi infection associated with spontaneous abortion in an
endemic Italian area.
NLM PUBMED CIT. ID: 3252658 NLM CIT. ID: 89300130
SOURCE:
Acta Eur Fertil 1988 Sep-Oct;19(5):279-81
TITLE:
[Multiple neurologic manifestations of Borrelia burgdorferi infection]
VERNACULAR TITLE:
Les multiples manifestations neurologiques des infections a Borrelia
burgdorferi.
AUTHORS:
Dupuis MJ
AUTHOR AFFILIATION:
Clinique St-Pierre, Ottignies, Belgique.
ABSTRACT:
The neurological spectrum of Borrelia burgdorferi infections is still
enlarging. We review epidemiological, pathological and serological
data of Lyme disease. The course of the disease is divided in three
stages: stage 1 during the first month is characterised by erythema
chronicum migrans and associated manifestations; stage 2 includes not
only the classical European meningoradiculitis but also less specific
neurological symptoms: isolated lymphocytic meningitis with an acute
or even relapsing course, apparently idiopathic facial palsy,
neuritis of other cranial nerves, polyneuritis cranialis,
Argyll-Robertson sign, peripheral nerve involvement, acute transverse
myelitis, severe encephalitis, myositis. During stage 3, three to
five months or longer after the onset of the disease, chronic
arthritis, acrodermatitis chronica atrophicans and various
neurological symptoms can be observed: chronic neuropathy with mainly
sensory or motor signs, recurrent strokes due to cerebral angiopathy
and progressive encephalomyelitis; this third stage the central
nervous system involvement is characterised by slowly progressive or
fluctuating course during months or years, ataxic or spastic gait
disorder, bladder disturbances, cranial nerve dysfunction including
optic atrophy and hypoacusia, dysarthria, focal and diffuse
encephalopathy. This chronic central nervous system disease can mimic
multiple sclerosis, anorexia nervosa, psychic disorders or subacute
presenile dementia. It is often associated with pleiocytosis,
abnormal EEG and evoked potentials, sometimes multifocal and mainly
periventricular white matter lesions visualised by CT or MRI, and as
a rule high antibody titers against Borrelia burgdorferi. High doses
of penicillin can halt the disease, sometimes induce spectacular
regression of symptoms or sometimes be inefficient; ceftriaxone could
be a more powerful therapy.
Similarities between syphilis and
Borreliosis are multiple: both of these spirochetes contain plasmids,
can be transmitted through the placenta
and progress for many years
through successive stages, with multiorgan symptoms, including
parenchymatous and vascular lesions of the central nervous system.
Borrelia burgdorferi is the new great imitator.
NLM PUBMED CIT. ID: 3070690 NLM CIT. ID: 89186273
SOURCE:
Rev Neurol (Paris) 1988;144(12):765-75
TITLE:
Lyme disease during pregnancy.
AUTHORS:
Markowitz LE; Steere AC; Benach JL; Slade JD; Broome CV
ABSTRACT:
Lyme disease is an increasingly recognized tick-borne illness caused
by a spirochete, Borrelia burgdorferi. Because the etiologic agent of
Lyme disease is a spirochete, there has been concern about the effect
of maternal Lyme disease on pregnancy outcome. We reviewed cases of
Lyme disease in pregnant women who were identified before knowledge
of the pregnancy outcomes. Nineteen cases were identified with onset
between 1976 and 1984. Eight of the women were affected during the
first trimester, seven during the second trimester, and two during
the third trimester; in two, the trimester of onset was unknown.
Thirteen received appropriate antibiotic therapy for Lyme disease.
Of the 19 pregnancies, five had adverse outcomes, including syndactyly,
cortical blindness, intrauterine fetal death, prematurity, and rash
in the newborn. Adverse outcomes occurred in cases with infection
during each of the trimesters.
Although B burgdorferi could not be
implicated directly in any of the adverse outcomes, the frequency of
such outcomes warrants further surveillance and studies of pregnant
women with Lyme disease.
NLM PUBMED CIT. ID: 2423719 NLM CIT. ID: 86227939
SOURCE:
JAMA 1986 Jun 27;255(24):3394-6
TITLE:
Fetal outcome in murine Lyme disease.
AUTHORS:
Silver RM; Yang L; Daynes RA; Branch DW; Salafia CM; Weis JJ
AUTHOR AFFILIATION:
Department of Obstetrics and Gynecology, University of Utah School of
Medicine, Salt Lake City 84132.
ABSTRACT:
Lyme disease is an inflammatory syndrome caused by infection with
Borrelia burgdorferi. Although this syndrome has important
implications for human pregnancy, little is known about gestational
infection with B. burgdorferi.
Fetal death occurred in 33 of 280
gestational sacs (12%) in 39 C3H/HeN female mice infected by
intradermal injection of B. burgdorferi 4 days after mating (acute
infection), compared with 0 of 191 sacs in 25 control mice (P =
0.0001). Forty-six percent of acutely infected mice suffered at least
one fetal death, compared with none of the control animals (P =
0.0002).
There were no fetal deaths in 18 C3H/HeN mice infected 3
weeks prior to mating (chronic infection). A sensitive PCR technique
detected B. burgdorferi DNA in the uteri of acutely infected mice but
did not detect DNA in the uteri of controls or chronically infected
mice. Spirochete DNA was only rarely detected in fetal tissues, and
its presence was not required for fetal death. The inclusion of an
internal competitive PCR target indicated that the lack of B.
burgdorferi sequences in fetal DNA was not due to the presence of a
PCR inhibitor. Histologic analysis of gestational tissues from
infected animals demonstrated nonspecific pathology consistent with
fetal death.
These findings indicate an association between murine
fetal death and acute infection with B. burgdorferi early in
gestation but not with chronic infection. Our data suggest that fetal
death is due to a maternal response to infection rather than fetal
infection. These findings could provide an explanation for
observations in humans in which sporadic cases of fetal death in
women infected with B. burgdorferi during pregnancy have been
reported, while previous infection has not been associated with fetal
death.
NLM PUBMED CIT. ID: 7806385 NLM CIT. ID: 95105028
SOURCE:
Infect Immun 1995 Jan;63(1):66-72
TITLE:
Intrauterine transmission of Borrelia burgdorferi in dogs.
AUTHORS:
Gustafson JM; Burgess EC; Wachal MD; Steinberg H
AUTHOR AFFILIATION:
Department of Medical Sciences, University of Wisconsin-Madison,
School of Veterinary Medicine 53706.
ABSTRACT:
To determine whether intrauterine transmission of Borrelia burgdorferi
could exist in dogs, 10 female Beagles were inoculated intradermally
with approximately 1,000 B burgdorferi on day 1 of proestrus;
inoculation was repeated every 2 weeks during the gestation period.
Ten female control Beagles were similarly inoculated with
phosphate-buffered saline solution. Prior to the start of the study,
all females and 3 males used for breeding were seronegative for B
burgdorferi on the basis of results of the indirect fluorescent
antibody test and immunoblot (western analysis. Similarly, results of
culture of blood for B burgdorferi were negative. All 20 of the
females were bred naturally. Blood samples were collected weekly for
serologic testing and culture. Blood samples were obtained from live
pups on day 1 of life, then weekly until pups were 6 weeks old when
they were euthanatized. Tissues were obtained for culture and testing
by use of polymerase chain reaction (PCR). Of 10
spirochete-inoculated (SI) females, 8 became infected with B
burgdorferi as evidenced by spirochete culture results and/or
PCR-detected B burgdorferi DNA in the tissues of females or their
pups.
Of the 10 SI females, 8 delivered litters (3 to 7 pups) that
had at least 1 neonatal or 6-week-old pup with B burgdorferi
DNA-positive tissues (by PCR), and spirochetes were cultured from
tissues from pups of 2 litters.
(ABSTRACT TRUNCATED AT 250 WORDS)
NLM PUBMED CIT. ID: 8323057 NLM CIT. ID: 93311737
SOURCE:
Am J Vet Res 1993 Jun;54(6):882-90
TITLE:
Borrelia burgdorferi infection in dairy cows, rodents, and birds from four Wisconsin dairy farms.
AUTHORS:
Burgess EC; Wachal MD; Cleven TD
AUTHOR AFFILIATION:
Department of Medical Science, University of Wisconsin, School of
Veterinary Medicine, Madison 53706.
ABSTRACT:
A combination of culture and subsequent spirochete identification with
the polymerase chain reaction technique was used to identify cows,
rodents, and birds infected with Borrelia burgdorferi. Animals were
trapped on four Wisconsin dairy farms during the summer of 1990.
Farms 1 and 2 were located in counties nonendemic for Lyme disease
and Farms 3 and 4 were located in counties endemic for Lyme disease.
The results of the rodent and bird samples were as follows given as
the number yielding organisms number tested: Farm 1, 1/17 Mus
musculus and 2/52 Peromyscus domesticus; Farm 2, 4/49 M. musculus,
1/2 P. maniculatus, 1/1 P. leucopus, and 1/35 P. domesticus; Farm 3,
0/27 M. musculus, 0/5 P. leucopus, 0/12 P. maniculatus and, 3/58 P.
domesticus; and Farm 4, 1/24 M. musculus, 2/19 P. leucopus, 1/12
Microtus pennsylvanicus, and 0/17 P. domesticus.
One P. leucopus and
one M. musculus from Farm 2 were pregnant and fetal tissues from both
were positive.
Cow blood sample results were as follows: Farm 1, 7/47
in July, and 2/45 in August; Farm 2, 0/28 in August and 0/23 in
October; Farm 3, 0/13 in July and 1/18 in August 29; and Farm 4, 3/45
in August. Ticks were found on rodents on Farm 4 and on one bird on
Farm 3. Spirochetemic cows, rodents, and birds were found in non-Lyme
endemic counties suggesting that alternate modes of transmission
other than by ticks may be important.
Transplacental transmission was
shown in M. musculus and P. leucopus.
NLM PUBMED CIT. ID: 8362496 NLM CIT. ID: 93369938
SOURCE:
Vet Microbiol 1993 May;35(1-2):61-77
TITLE:
Borrelia sp. infection in coyotes, black-tailed jack rabbits and desert cottontails in southern Texas.
AUTHORS:
Burgess EC; Windberg LA
AUTHOR AFFILIATION:
Department of Medical Sciences, School of Veterinary Medicine,
University of Wisconsin, Madison 53706.
ABSTRACT:
Coyotes (Canis latrans) from southern Texas were sampled for
antibodies to Borrelia burgdorferi from 1980 to 1986; black-tailed
jack rabbits (Lepus californicus) and desert cottontails (Sylvilagus
audubonii) were sampled in 1986. Coyote fetuses, adult coyote
kidneys, and black-tailed jack rabbit and desert cottontail kidneys
were cultured for B. burgdorferi in 1986. Results of indirect
immunofluorescent antibody (IFA) tests for B. burgdorferi in coyotes
were as follows (number positive at a dilution of greater than or
equal to 1:128/number tested): 1980 (0 of 30), 1981 (0 of 21), 1982
(0 of 53), 1983 (0 of 78), 1984 (47 of 97), 1985 (20 of 88), and 1986
(42 of 80). Eight of 26 black-tailed jack rabbits and two of seven
desert cottontails tested in 1986 had IFA titers to B. burgdorferi of
greater than or equal to 1:128.
Borrelia burgdorferi was isolated
from one of five coyote fetuses, three of 31 adult coyote kidneys,
and two of 10 black-tailed jack rabbit kidneys in 1986. These results
indicate that B. burgdorferi infection has been present in coyotes in
Texas, at least since 1984 and that transplacental transmission
occurs.
NLM PUBMED CIT. ID: 2644452 NLM CIT. ID: 89125773
SOURCE:
J Wildl Dis 1989 Jan;25(1):47-51
TITLE:
Borrelia burgdorferi infection in Wisconsin horses and cows.
AUTHORS:
Burgess EC
AUTHOR AFFILIATION:
School of Veterinary Medicine, University of Wisconsin, Madison 53706.
ABSTRACT:
Blood samples from Wisconsin horses and cows suspected of having
clinical disease due to Borrelia burgdorferi infection were submitted
by veterinary practitioners. All serum, milk, colostrum, and synovial
samples were tested for B. burgdorferi antibodies by
immunofluorescence. Whole blood, milk, colostrum, and synovial fluid
samples were cultured for B. burgdorferi. Records were kept on the
clinical signs of antibody-positive animals, date of sample, and
location of the animal by county. Of the samples tested for
antibodies 282/430 cow sera, 118/190 horse sera, 5/10 cow synovial
fluids, 3/6 horse synovial fluids, 2/3 cow colostrums, 0/44 cow milk
samples and
1 aborted fetus serum were antibody positive at a titer
of 1:128 or greater.
Of samples cultured 7/156 cow bloods, 2/35 horse
bloods, 1/14 cow synovial fluids, 0/4 synovial fluids, 1/3 cow
colostrums, 0/44 cow milk, and 2/10 cow urine samples were B.
burgdorferi culture positive. For both cows and horses October and
May were the two peak months for the number of antibody-positive
samples. The most frequent clinical signs in antibody-positive horses
and cows were lameness and swollen joints, but many also had
stiffness, laminitis, abortions, and fevers. Not all
antibody-positive animals showed clinical signs. These findings show
that B. burgdorferi infection occurs in horses and cows and can cause
clinical illness in some but not all animals. Infection in cows and
horses occurs most frequently 1 month after the emergence of adult I.
dammini. Because spirochetes could be isolated from blood, synovial
fluid, colostrum, and urine, these animals could be important in
providing an infected blood meal for ticks and bringing B.
burgdorferi in direct contact with humans.
NLM PUBMED CIT. ID: 3190095 NLM CIT. ID: 89048796
SOURCE:
Ann N Y Acad Sci 1988;539:235-43
TITLE:
Seasonal prevalence of Borrelia burgdorferi in natural populations of white-footed mice, Peromyscus leucopus.
AUTHORS:
Anderson JF; Johnson RC; Magnarelli LA
ABSTRACT:
Borrelia burgdorferi, the etiologic agent of Lyme disease, was
isolated from 111 of 237 Peromyscus leucopus captured during all
seasons of the year.
Borreliae were cultured from tissues of the
spleen (101 mice), left kidney (76 mice), and right kidney (73 mice),
from blood (12 mice), and from one fetus.
Mice were infected during
the winter, when immature Ixodes dammini were inactive. The
prevalence of infection during the winter (less than or equal to 33%)
was more than twofold lower than that during the summer (ca. 75%), a
time when nymphal ticks are abundant. Overwintering, infected mice
are reservoir hosts for subadult ticks that begin feeding in early
spring. Twenty white-footed mice from which B. burgdorferi was
isolated from tissues of spleen or kidney but not from blood were
parasitized by larval I. dammini or Dermacentor variabilis which
harbored borreliae. We conclude that these mice were infectious to
feeding ticks, even though borreliae were not isolated from blood.
NLM PUBMED CIT. ID: 3624451 NLM CIT. ID: 87308743
SOURCE:
J Clin Microbiol 1987 Aug;25(8):1564-6
TITLE:
Update: Lyme disease and cases occurring during pregnancy--United States.
See full-text article at:
CDC MMWR: Lyme Disease and Cases Occurring during Pregnancy -- US, June 28, 1985
NLM PUBMED CIT. ID: 3925314 NLM CIT. ID: 85240257
SOURCE:
MMWR Morb Mortal Wkly Rep 1985 Jun 28;34(25):376-8, 383-4
[No abstract available.]
TITLE:
Neonatal skin lesions due to a spirochetal infection: a case of congenital Lyme borreliosis?
AUTHORS:
Trevisan G; Stinco G; Cinco M
AUTHOR AFFILIATION:
Institute of Dermatology, University of Trieste, Italy.
NLM PUBMED CIT. ID: 9352409 NLM CIT. ID: 98013686
SOURCE:
Int J Dermatol 1997 Sep;36(9):677-80
[No abstract available.]
TITLE:
[Pathology of pregnancy and the fetus in Lyme disease]
VERNACULAR TITLE:
Patologiia beremennosti i ploda pri bolezni Laima.
AUTHORS:
Elsukova LV; Korenberg EI; Kozin GA
NLM PUBMED CIT. ID: 7715559 NLM CIT. ID: 95231409
SOURCE:
Med Parazitol (Mosk) 1994 Oct-Dec;(4):59-62
[No abstract available.]
TITLE:
Lyme disease during pregnancy. ACOG Committee Opinion: Committee on Obstetrics: Maternal and Fetal Medicine. Number 99--November 1991.
AUTHORS:
NLM PUBMED CIT. ID: 1358705 NLM CIT. ID: 93050632
SOURCE:
Int J Gynaecol Obstet 1992 Sep;39(1):59-60
[No abstract available.]
TITLE:
Lyme disease: a review with emphasis on the pregnant woman.
AUTHORS:
Smith LG Jr; Pearlman M; Smith LG; Faro S
AUTHOR AFFILIATION:
Department of Obstetrics and Gynecology, Baylor College of Medicine,
Houston, Texas 77030.
NLM PUBMED CIT. ID: 2014072 NLM CIT. ID: 91194878
SOURCE:
Obstet Gynecol Surv 1991 Mar;46(3):125-30
[No abstract available.]
TITLE:
Lyme disease during pregnancy.
AUTHORS:
Edly SJ
AUTHOR AFFILIATION:
Department of Obstetrics and Gynecology, UMDNJ-Robert Wood Johnson
Medical School, New Brunswick 08903.
NLM PUBMED CIT. ID: 2200981 NLM CIT. ID: 90349122
SOURCE:
N J Med 1990 Jul;87(7):557-60
TITLE:
Lyme borreliosis during pregnancy.
AUTHORS:
Stiernstedt G
AUTHOR AFFILIATION:
Department of Infectious Diseases, Danderyd Hospital, Sweden.
NLM PUBMED CIT. ID: 2287925 NLM CIT. ID: 91142741
SOURCE:
Scand J Infect Dis Suppl 1990;71:99-100
[No abstract available.]
TITLE:
Lyme disease and pregnancy.
AUTHORS:
Cartter ML; Hadler JL; Gerber MA; Mofenson L
NLM PUBMED CIT. ID: 2758822 NLM CIT. ID: 89337701
SOURCE:
Conn Med 1989 Jun;53(6):341-2
[No abstract available.]
TITLE:
Borrelia burgdorferi in a newborn despite oral penicillin for Lyme borreliosis during pregnancy.
AUTHORS:
Weber K; Bratzke HJ; Neubert U; Wilske B; Duray PH
AUTHOR AFFILIATION:
Department of Medicolegal Medicine, Dermatology and Microbiology,
University of Munich, Federal Republic of Germany.
NLM PUBMED CIT. ID: 3130607 NLM CIT. ID: 88217405
SOURCE:
Pediatr Infect Dis J 1988 Apr;7(4):286-9
[No abstract available.]
TITLE:
[Lyme disease in pregnancy]
VERNACULAR TITLE:
Lymska nemoc v tehotenstvi.
AUTHORS:
Andrasova V; Svarovsky J; Matousek B
NLM PUBMED CIT. ID: 3370692 NLM CIT. ID: 88223439
SOURCE:
Cesk Gynekol 1988 Feb;53(1):39-41
[No abstract available.]
TITLE:
Stillbirth following maternal Lyme disease.
AUTHORS:
MacDonald AB; Benach JL; Burgdorfer W
NLM PUBMED CIT. ID: 3480464 NLM CIT. ID: 88095529
SOURCE:
N Y State J Med 1987 Nov;87(11):615-6
[No abstract available.]
TITLE:
Lyme disease during pregnancy.
AUTHORS:
Mikkelsen AL; Palle C
AUTHOR AFFILIATION:
Department of Gynecology and Obstetrics, Hvidovre Hospital, University
of Copenhagen, Denmark.
NLM PUBMED CIT. ID: 3425250 NLM CIT. ID: 88102547
SOURCE:
Acta Obstet Gynecol Scand 1987;66(5):477-8
[No abstract available.]
TITLE:
Human fetal borreliosis, toxemia of pregnancy, and fetal death.
AUTHORS:
MacDonald AB
NLM PUBMED CIT. ID: 3554838 NLM CIT. ID: 87208538
SOURCE:
Zentralbl Bakteriol Mikrobiol Hyg [A] 1986 Dec;263(1-2):189-200
[No abstract available.]
TITLE:
Leads from the MMWR. Update: Lyme disease and cases occurring during pregnancy.
NLM PUBMED CIT. ID: 4009904 NLM CIT. ID: 85237877
SOURCE:
JAMA 1985 Aug 9;254(6):736-7, 741
[No abstract available.]
TITLE:
Maternal-fetal transmission of the Lyme disease spirochete, Borrelia burgdorferi.
AUTHORS:
Schlesinger PA; Duray PH; Burke BA; Steere AC; Stillman MT
NLM PUBMED CIT. ID: 4003991 NLM CIT. ID: 85223525
SOURCE:
Ann Intern Med 1985 Jul;103(1):67-8
[No abstract available.]
Last updated on 23 June 2000 by
Art Doherty
Lompoc, California
[email protected]
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