WELCOME TO THE HOMEPAGE OF Dr. P. YOGEESWARI

 

        

Recently Shifted to BITS-Pilani, Hyderabad Campus

 

 

          Mailing Address:

        Dr. P. Yogeeswari

    Assistant Professor & Group Leader,

                      Pharmacy Group,

                      Warden, Meera Bhawan (Girls Hostel),

                      Nucleus Member, Research & Consultancy Division

                      Birla Institute of Technology & Science- Pilani, Hyderabad Campus

                                         Jawahar Nagar, Shameerpet Mandal, R.R. District,

                                                   Pin-500078, INDIA

                                         Telephone: +91-9010202833 (O)

                                                              +91-9705932091(R)

 Email: [email protected]; [email protected]

 

 

Favorite Quote:

“There are two kinds of people; those who do the work and those who take the credit.

Try to be in the first group; there is less competition.”

- Indira Gandhi

The most dynamic women of the twentieth century

Education

Ph. D. (Medicinal Chemistry), Banaras Hindu University, Varanasi, India, 2001.

Master of Pharmacy (Medicinal Chemistry), Banaras Hindu University, India, 1998.

Bachelor of Pharmacy, The Tamilnadu Dr. M.G.R. Medical University, Chennai, India, 1996 (State Topper, Gold medalist).

Details of Professional Experience

Involved in Research since1997

Involved in Teaching since 1998

Details of employment (past & present)

Served as Lecturer at Ultra College of Pharmacy, Madurai, Tamilnadu, India,  for 10 months in 1998.

Serving Birla Institute of Technology & Science, Pilani, Rajasthan, India,  as Lecturer since March 2001 and as Assistant Professor since Feb 2005.

Research Activities

Research Area

The major thrust of my research lies at the crossroads of chemistry, and biology. My current research efforts are focused in the anticonvulsant drug design based on molecular modeling, structure-based drug design, and rational approach like pharmacophore-based design and virtual database screening for development of new drugs. My group is currently working on three general drug development areas with the focus aimed at the elucidation of the mechanisms of novel anticonvulsant, antitubercular, and  compounds useful for the trreatment of neuropathic pain.

The research is also focused in determining the molecular mechanism of certain anticonvulsant compounds and antiallodynic agents in the rat brain. Our work focuses on the design of novel antiallodynic and antihyperalgesic agents for the treatment of neuropathic pain and computer-aided design of novel antimycobacterials.

Drug Discovery, Design and Synthesis of

Anticonvulsants (Prodrugs, Aryl semicarbazones & Heterocylic compounds)

Anticancer compounds (Metal complexes of Aryl thiosemicarbazones, Quinolones, Semicarbazones & Prodrugs)

Newer Drugs for Neuropathic Pain treatment

Molecular Modeling and Docking Studies on

Anticonvulsants

Anti-HIV agents

Antitubercular agents

NeuroPharmacology, Toxicology, and Enzyme Inhibition Studies covering

Collaborative Research Scientist at

National Institute of Health, Bethesda, USA

National Cancer Institute, USA

National Institute of Mental Health and Neurosciences, Bangalore, India

Indian Institute of Science, Bangalore, India.

Department of Ophthalmology & Visual Science, University of Illinois, Chicago, USA

 

Research funding Received

 

 

Grant agency

Title of the project and Reference number

Duration,

 

Amount

DST SERC FAST TRACK UNDER YOUNG SCIENTIST SCHEME

 

(PRINCIPAL INVESTIGATOR)

DESIGN OF NEW ANTICONVULSANTS: SYNTHESIS AND PHARMACOLOGICAL EVALUATION OF ARYL SEMICARBAZONES AND ITS ANALOGUES 

 2004-2007

 Rs. 4.58 lacs

COUNCIL OF INDUSTRIAL & SCIENTIFIC RESEARCH

 (PRINCIPAL INVESTIGATOR) SYNTHESIS AND NEUROPHARMACOLOGY OF 4-AMINOBUTYRIC ACID ANALOGUES

2005-2008

Rs. 8.96 lacs
UNIVERSITY GRANTS COMMISSION

 (PRINCIPAL INVESTIGATOR)      DESIGN AND SYNTHESIS OF NEWER GABA ANALOGUES FOR TREATING CNS DISORDERS

2007-2010 

 Rs. 8.11 lacs
DEPARTMENT OF BIOTECHNOLOGY

 (CO-INVESTIGATOR)                  VIRTUAL CENTRE OF EXCELLENCE FOR TUBERCULOSIS RESEARCH

(In collaboration with Indian Institute of Science, Bangalore & The Foundation for Medicial Research, Mumbai)

2008-2012 

 Rs. 39.6 lacs

(Total 10.0667 crore project)
COUNCIL OF INDUSTRIAL & SCIENTIFIC RESEARCH

 (CO-INVESTIGATOR)      DEVELOPMENT OF NEW GENERATION QUINOLONE MOLECULES AGAINST MYCOBACTERIUM TUBERCULOSIS

2005-2008

Rs. 7.96 lacs

INDIAN COUNCIL OF MEDICAL RESEARCH

       (CO-INVESTIGATOR)             DESIGN AND SYNTHESIS OF NOVEL NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS FOR THE TREATMENT OF AIDS AND OPPORTUNISTIC INFECTIONS ASSOCIATED WITH AIDS INCLUDING TUBERCULOSIS TUBERCULOSIS

2006-2009 

 Rs. 10 lacs

                                

Research Students

Ph.D.:

  1. Ms. Shalini Mehta on “SYNTHESIS AND STRUCTURE-ACTIVITY RELATIONSHIP OF NEW ARYL AND HETEROARYL SEMICARBAZONES AS ANTICONVULSANTS”- Completed.

  2. Presently guiding Mr. J.Vaigunda Raghavendran (UGC Junior Research Fellow) on "DESIGN OF GABA ANALOGUES AS ANTICONVULSANTS - SYNTHESIS & NEUROPHARMACOLOGY"- Completed.

  3. Presently guiding Mr. A.S.K. Reddy (CSIR Senior Research Fellow)  on "SYNTHESIS AND NEUROPHARMACOLOGY OF 4-AMINOBUTYRIC ACID ANALOGUES"

  4. Presently guiding Mr. Arvind Semwal (UGC Senior Research Fellow) on "PHARMACOLOGICAL INTERVENTIONS TO IDENTIFY POTENTIAL DRUG CANDIDATES FOR THE TREATMENT OF NEUROPATHIC PAIN"

  5. Presently guiding Mr. Pritesh Bhat (DBT Junior Research Fellow) on " DESIGN OF VARIOUS NEW ENZYME INHIBITORS AS ANTIMYCOBACTERIAL AGENTS USING IN-SILICO HIGH THROUGHPUT SCREENING"

 

M.Pharm projects: 30

 

B.Pharm Project students: 66

 

Professional Recognition, Awards, Fellowships Received

  1. Recipient of "YOUNG PHARMACY TEACHER OF THE YEAR 2007" awarded by the Association of Pharmacy Teachers of India.

  2. Editorial Advisory Board Member of an international journal, "Recent Patents on CNS Drug Discovery" published by Bentham Science Publishers (USA & The Netherlands).

  3. Editorial Board Member of an international journal "International Journal of Biomedical Sciences" published by Master publishing group, USA.

  4. Best Paper in Podium presentation was awarded in the 11th APTI national Convention held in September 1-3, 2006 at Bangalore for the paper entitled "Synthesis of 4-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-N-(substituted phenyl)butanamides possessing antiallodynic and antihyperalgesic activities in two rat models of neuropathic pain".

  5. Recipient of "Young Scientist" award by Department of Science & Technology, Government of India under Fast track Funding scheme.

  6. Biographical profile included in the prestigious registry of the 7th edition of “Marquis Who’s Who in Science and Engineering”, 2003-2004 USA and regularly updated.

  7. Biographical profile included in the prestigious registry of the 1th edition of “Marquis Who’s Who in Asia”, 2006-2007 USA.

  8. Life Member of Association of Pharmacy Teachers of India.

  9. Life Member, Indian Pharmacological Society.

  10. Member, International Brain research Organization.

  11. Recipient of “Sevaratna” Dr. R.Venkatesalu Gold Medal for securing First rank in B.Pharm of The Tamilnadu Dr. M.G.R. Medical University.

  12. Recipient of Tamilnadu Pharmacy Scientific Trust, Chennai Gold Medal for Topper in B.Pharmacy in the Tamilnadu State.

  13. Recipient of First Prize award in Tamilnadu State for B.Pharmacy awarded by The Tamilnadu Pharmacy Council, Chennai.

  14. Awarded Junior Fellowship by the UGC during the period 1996-1998.

  15. Awarded Senior Research Fellowship by the UGC during the period 2000-2001.

  16. Member, Canadian Pharmaceutical society.

 

List of Significant Publications   

 

  1. S.N.Pandeya, P.Yogeeswari, D.Sriram, G.Nath; synthesis and antimicrobial activity of N-Mannich bases of 3-[N’-sulphadoximino] Isatin and its methyl derivative, Boll. Chim. Farm. 137(8), 321-324, 1998.
  2. S.N. Pandeya, P.Yogeeswari, D. Sriram, E. De Clercq, C. Pannecouque, M. Witvrouw; Synthesis and Screening for Anti-HIV activity of some N-Mannich bases of isatin derivatives, Chemotherapy, 45, 192-196, 1999.
  3. S.N.Pandeya, P. Yogeeswari, J.P. Stables, Synthesis and anticonvulsant activity of 4-bromophenyl substituted aryl semicarbazones, Eur. J. Med. Chem., 35, 879-886, 2000.
  4. S.N.Pandeya, P. Yogeeswari, E.A.Sausville, A.B.Mauger, V.L.Narayanan, Synthesis and antitumour activity of some aryl semicarbazones, Sci. Pharm. 68, 369-377, 2000.
  5. S.N. Pandeya, D. Sriram, P.Yogeeswari, S. Ananthan; Antituberculous activity of Norfloxacin Mannich bases with Isatin derivatives, Chemotherapy, 47, 266-269, 2001.
  6. S.N.Pandeya, D. Sriram, P. Yogeeswari, J.P. Stables; Anticonvulsant and Neurotoxicity evaluation of 5-(un)-substituted isatinimino derivatives, Pharmazie, 56, 875-878, 2001.
  7. S.N.Pandeya, P. Yogeeswari, E.A.Sausville, A.B.Mauger, V.L.Narayanan, Synthesis and antitumour evaluation of 4-bromophenyl semicarbazones, Arzneim. Forschung/ Drug Res., 52, 103-108, 2002.
  8. P.Yogeeswari, D.Sriram, L.R.J. Suniljit, S.S.Kumar, J.P.Stables; Anticonvulsant and neurotoxicity evaluation of some 6-chlorobenzothiazolyl-2-thiosemicarbazones, Eur. J. Med. Chem., 37, 231-236, 2002.
  9. D.Sriram, P.Yogeeswari, S.N.Pandeya, S. Ananthan; Antituberculous activity of isatin derivatives, Sci. Pharm., 70, 73-79, 2002.
  10. S.N.Pandeya, P.Yogeeswari, D.Sriram, G.Nath; Synthesis, Antibacterial and antifungal activities of N-Mannich bases of 3-[N2-pyrimethaminylimino] isatin, Ind. J. Pharm. Sci., 64, 209-212, 2002.
  11. D.Sriram, P.Yogeeswari, Towards the Design and Development of Agents with Broad Spectrum Chemotherapeutic Properties for the Effective Treatment of HIV / AIDS, Curr. Med. Chem. 10, 1909-1915, 2003
  12. P.Yogeeswari, D.Sriram, V.Saraswat, J.Vaigunda Ragavendran, M.Mohan Kumar, S.Murugesan, R.Thirumurugan, J.P.Stables, Synthesis and Anticonvulsant and Neurotoxicity Evaluation of N4 –Phthalimido Phenyl (Thio) Semicarbazides, Eur. J. Pharm. Sci., 20, 341-346, 2003.
  13. D. Sriram, P. Yogeeeswari, N. Srichakravarthy, Tanushree Ratan Bal,  Synthesis of Stavudine Amino acid Ester Prodrugs with Broad-Spectrum Chemotherapeutic Properties for the Effective Treatment of HIV/AIDS, Bioorg. Med. Chem. Lett., 14, 1085-1087,  2003.
  14. P.Yogeeswari, D.Sriram, A.Brahmandam, I.Sridharan, R.Thirumurugan and J.P. Stables, Synthesis of novel aryl semicarbazones as anticonvulsants with GABA-mediated mechanism, Med. Chem. Res., 12, 57-68, 2003.
  15. D. Sriram, V. S. Rao, K. V. G. Chandrasekhar and P. Yogeeswari, Progress in the research of artemisinin and its analogues as anti-malarials: an update, Nat. Prod. Res., 18, 503-527, 2004.  
  16. D. Sriram, K. Jyothi Mallika and P. Yogeeswari, Synthesis of Tetrahydro-2H-[1, 3, 5] thiadiazine-5-(4-pyridylcarboxamido)-2-thione with antitubercular activity, Sci. Pharm., 75, 35-41, 2004.
  17. P.Yogeeswari, D.Sriram, R.Thirumurugan, R.Kavya, S.Samuel, J.P.Stables, 3-Chloro-2-methylphenyl semicarbazones: Synthesis and anticonvulsant activity, Eur. J. Med. Chem., 39, 729-734, 2004.
  18. P. Yogeeswari, D. Sriram, S.N. Pandeya, J.P. Stables, 4-Sulphamoylphenyl semicarbazones with anticonvulsant activity, IL Farmaco, 59, 609-613, 2004.
  19. D.Sriram, P.Yogeeswari, Antituberculous activity of semicarbazone derivatives, Bioorg Med. Chem. Lett., 14, 3923-3924, 2004.
  20. P. Yogeeswari, J. Vaigunda Ragavendran, R. Thirumurugan, A. Saxena, D. Sriram, Ion channels as important targets for antiepileptic drug design, Curr. Drug Targets, 5, 589-602, 2004.
  21. D. Sriram, T. R. Bal, P. Yogeeswari, Design, synthesis and biological evaluation of novel non- nucleoside HIV-1 reverse transcriptase inhibitors with broad-spectrum chemotherapeutic properties, Bioorg. Med. Chem., 12, 5865-5873, 2004.
  22. P. Yogeeswari, D. Sriram, S. Mehta, D. Nigam, M. Mohan Kumar, S. Murugesan, J.P. Stables, Anticonvulsant and neurotoxicity evaluation of some 6-substituted benzothiazolyl-2-thiosemicarbazones, Farmaco, 60, 1-5, 2005.
  23. P. Yogeeswari, D. Sriram, J.V. Raghavendran, R. Thirumurugan, The GABA shunt: An attractive and potential therapeutic target in the treatment of epileptic disorders, Curr. Drug Metabolism, 6, 127-139, 2005.
  24. D. Sriram, P. Yogeeswari, R.Thirumurugan, T. R. Bal,  Camptothecin and its analogues: A review on their chemotherapeutic potential. Nat. Prod. Res., Preview published, 2005.
  25. P. Yogeeswari and D. Sriram, Betulinic acid and its derivatives: A review on their biological properties, Curr. Med. Chem., 12, 656-666, 2005.
  26.  P.Yogeeswari, D.Sriram, V.Veena, R.Kavya, K.Rakhra, S.Mehta, J.VaigundaRagavendran, R.Thirumurugan, J.P.Stables, Synthesis of Novel Aryl semicarbazones as Potential Anticonvulsant Agents, Biomed. Pharmacother., 59, 51-55,  2005.
  27. D. Sriram, P.Yogeeswari, A.N. Nagappa, Combinatorial Synthesis of Some HIV-1 Reverse Transcriptase and Protease Inhibitors, Comb. Chem. High Throughput Screen., 8(6), 377-385, 2005.
  28. D. Sriram, T. R. Bal, P. Yogeeswari, Aminopyrimidinimino isatin analogues: Design and synthesis of novel non- nucleoside HIV-1 reverse transcriptase inhibitors with broad-spectrum anti-microbial properties, Med. Chem., 1, 277-285, 2005.
  29. D. Sriram, T. R. Bal, P. Yogeeswari, Newer aminopyrimidinimino isatin analogues as non-nucleoside HIV-1 reverse transcriptase inhibitors for HIV and other opportunistic infections of AIDS: Design, synthesis and biological evaluation, Farmaco, 60, 377-384, 2005.
  30. D. Sriram, P. Yogeeswari, T.G. Ashok Kumar, Microwave-assisted synthesis, and anti-YFV activity of 2, 3-diaryl-1, 3-thiazolidin-4-ones, J. Pharm. Pharm. Sci., 8, 429-466, 2005.
  31. D. Sriram, P. Yogeewari and K. Madhu, Synthesis and in-vitro antimycobacterial activity of some isonicotinyl hydrazones, Bioorg. Med. Chem. Lett.,  15, 4502-4505, 2005.
  32. T.R. Bal, B. Anand, P. Yogeeswari, D. Sriram, Synthesis and evaluation of anti-HIV activity of isatin b-thiosemicarbazone derivatives, Bioorg. Med. Chem. Lett., 15, 4451-4455,  2005.
  33. P. Yogeeswari, D. Sriram, R. Thirumurugan, J.V. Ragavendran, K. Sudhan, Roheeth Kumar, J. Stables, Discovery of N-(2,6-dimethylphenyl) substituted semicarbazonesas anticonvulsants: Hybrid pharmacophore-based design, J. Med. Chem., 48, 6202-6211, 2005.
  34. D. Sriram, P. Yogeeswari, N. Srichakravarthy, T. R. Bal, Synthesis of zidovudine prodrugs with broad-spectrum chemotherapeutic properties for the effective treatment of HIV/AIDS, Biomed. Pharmacother. 59,  452-455, 2005.
  35. D. Sriram, P. Yogeeswari, N. Srichakravarthy, T. R. Bal, Nevirapine derivatives with broad spectrum chemotherapeutic properties for the effective treatment of HIV / AIDS, Biomed. Pharmacother., 59, 456-459, 2005.
  36. D. Sriram, P. Yogeeswari, T.G. Ashok Kumar, Microwave-assisted synthesis, anti-HIV activity of 2, 3-diaryl-1, 3-thiazolidin-4-ones, Ind. J. Pharm. Sci., 67, 496-499, 2005.
  37. D. Sriram, P. Yogeeswari, T.G. Ashok Kumar, Microwave Assisted Synthesis, Anti-HIV, and Anti-YFV Activities of Schiff Bases of N-Hydroxy-N1-Aminoguanidine tosylate, Ind. J. Pharm. Sci., 67, 493-496, 2005.
  38. D. Sriram, T. R. Bal, P. Yogeeswari, Aminopyrimidinimino isatin analogues: Design of novel non- nucleoside HIV-1 reverse transcriptase inhibitors with broad-spectrum chemotherapeutic properties, J. Pharm. Pharm. Sci., 8, 565-577, 2005.
  39. P. Yogeeswari, D. Sriram, R. Kavya, S. Tiwari, Synthesis and in-vitro cytotoxicity evaluation of gatifloxacin Mannich bases, Biomed. Pharmacother., 59, 501-510, 2005.
  40. D. Sriram, T. R. Bal, P. Yogeeswari, Design, synthesis and biological evaluation of novel non- nucleoside HIV-1 reverse transcriptase inhibitors with broad-spectrum antimicrobial properties: Aminopyrimidinimino isatin analogues, Med. Chem. Res., 14, 211-228, 2005.
  41. D. Sriram, P. Yogeeswari, Gayatri Gopal, Synthesis, anti-HIV and antitubercular activities of lamivudine prodrugs, Eur. J. Med. Chem., 40, 1373-1376, 2005.
  42. D. Sriram, P. Yogeeswari, R. Thirumurugan, P. Roheeth Kumar, Discovery of Newer Antitubercular Oxazolyl thiosemicarbazones, J. Med. Chem., 49, 3448-3450, 2006.
  43. P. Yogeeswari, J.V. Ragavendran, D. Sriram, An Update on GABA Analogs for CNS Drug Discovery, Recent Patent Rev. CNS Drug Discov., 1, 113-118, 2006.
  44. P. Yogeeswari, D. Sriram, J. Vaigunda Raghavendran, R. Thirumurugan, S. Induja, J.P. Stables, Synthesis and structure-activity relationship on anticonvulsant aryl semicarbazones, Med. Chem. 2, 55-62, 2006.
  45. D. Sriram, P. Yogeeswari, K. Madhu, Synthesis and in vitro antitubercular activity of some 1-[(4-sub)phenyl]-3-(4-{1-[(pyridine-4-carbonyl)hydrazono]ethyl}phenyl)thiourea, Bioorg. Med. Chem. Lett., 16, 876-878, 2006.
  46. P. Yogeeswari, D. Sriram, A. Saxena, R. Thirumurugan, J. Stables, 2,4-Dimethoxyphenyl semicarbazones with anticonvulsant activity against three animal models of seizure: Synthesis and Pharmacological evaluation, Bioorg. Med. Chem.,  14, 3106-3112, 2006.
  47. D. Sriram, P. Yogeeswari, R.V. Devakram, Synthesis, in vitro and in vivo antimycobacterial activities of diclofenac acid hydrazones and amides, Bioorg. Med. Chem., 14, 3113-3118, 2006.
  48. D. Sriram, P. Yogeeswari, S.P. Reddy, Synthesis of Pyrazinamide Mannich bases and its antitubercular properties,  Bioorg. Med. Chem. Lett., 16, 2113-2116, 2006.
  49. D. Sriram, P. Yogeeswari, N.S. Myneedu, V. Saraswat, Abacavir prodrugs: Microwave-assisted synthesis and their evaluation of anti-HIV activities, Bioorg. Med. Chem. Lett., 16, 2127-2129, 2006.
  50. D. Sriram, P. Yogeeswari, K. Meena, Design, synthesis, anti-HIV and antitubercular activities of isatin derivatives, Pharmazie, 61, 271-274, 2006.
  51. D. Sriram, A. Aubry, P. Yogeeswari, L.M. Fischer,Gatifloxacin derivatives: Synthesis, antimycobacterial activities, and inhibition of Mycobacterium tuberculosis DNA gyrase, Bioorg. Med. Chem. Lett., 16, 2982-2985, 2006.  
  52. P. Yogeeswari, R. Thirumurugan, D. Sriram, L.R.J. Suniljit, J. Vaigunda Raghavendran, R. Kavya, K. Rakhra, J.P. Stables,  Synthesis of some new semicarbazone derivatives as anticonvulsants with GABA- mediated mechanism, Acta Pharm., 56, 259-272, 2006.
  53. P. Yogeeswari, D. Sriram, R.Thirumurugan, T. R. Bal, Epibatidine and its analogues as nicotinic acetylcholine receptor agonist: An update. Nat. Prod. Res., 20, 497-505, 2006.
  54. M. Shaharyar, A.A. Siddiqui, M. Asharaf Ali, D. Sriram, P. Yogeeswari, Synthesis and in-vitro antimycobacterial activity of N1-Nicotinoyl-3-(4’-hydroxy-3’-methyl phenyl)-5-[(sub)phenyl]-2-pyrazolines, Bioorg. Med. Chem. Lett., 16, 3947-3949, 2006.
  55. S. Mehta, P. Yogeeswari, P. Rohheth Kumar, D. Sriram, J. P. Stables, Heteroaryl-substituted semicarbazones: Synthesis and anticonvulsant activity of N-(3-Methylpyridin-2-yl)-substituted semicarbazones, J. Het. Chem., 43, 1287-1293, 2006.
  56. D. Sriram, P. Yogeeswari, M.R.K. Kishore, Synthesis and anti-HIV activity of nevirapine prodrugs, Pharmazie, 61, 895-897, 2006.
  57. S. Mehta, P. Yogeeswari, D. Sriram, P. Kudyar, P. Roheeth Kumar, S. Induja, J.P. Stables, Quantum Mechanical Modeling of N4-(2, 5-Disubstituted phenyl) Semicarbazones: Synthesis and Anticonvulsant Activity of N4-(2, 5-dimethylphenyl/-2-fluoro-5-methyl phenyl) Semicarbazones, Med. Chem., 2, 617-626, 2006.
  58. D. Sriram, T. R. Bal, P. Yogeeswari, D.R. Radha, V. Nagaraja, Evaluation of antimycobacterial and DNA gyrase inhibition of fluoroquinolone derivatives, J. Gen. App. Microbiol., 52, 195-200, 2006.
  59. M. Shaharyar, M. Asharaf Ali, D. Sriram, P. Yogeeswari, Synthesis and antimicrobial activity of 3-(4'-hydroxy-3'methylphenyl)-5-[(substituted)phenyl]-4,5-dihydro-1H-1-pyrazolyl-4-pyridylmethanone derivatives, Acta Pol. Pharm.-Drug Res., 63, 491-496, 2006.
  60. Shalini, P. Yogeeswari, D. Sriram, S. Induja, Microwave-assisted Synthesis, Anticonvulsant activity and Quantum Mechanical modeling of N-(4-Bromo-3-methylphenyl)semicarbazones, J. Zhejiang Univ. Section B, 8, 45-55, 2007.
  61. J.V. Ragavendran, I. Vikram Reddy, P. Yogeeswari, D. Sriram, Synthesis of 4-{[(3Z)-2-oxo-1,2-dihydro-3H-indol-3-ylidene]amino}-N-substituted phenyl) butanamides possessing antiallodynic and antihyperalgersic activities in two rat models of neuropathic pain, Med. Chem. Res., 15, 225-226, 2007.
  62. D. Banerjee, T.R. Bal, P. Yogeeswari, D. Sriram, L. Sebastin, A. Desai, S.N. Madhusudhana, V. Ravi, Isatin derivatives inhibit Japanese encephalitis virus entry and replication in-vitro, Med. Chem. Res., 15, 133-135, 2007.
  63. P. Senthil Kumar, M. Dinakaran, P. Yogeeswari, D. Sriram, Synthesis and antitubercular activities of 1-(cyclopropyl/t-butyl/4-fluorophenyl)-1,4-dihydro-6-nitro-4-oxo-7-(substituted secondary amines)-1,8-naphthyridine-3-carboxylic acid, Med. Chem. Res., 15, 281-282, 2007.
  64. D. Sriram, P. Yogeeswari, N. Raveendra Babu, K.N. Purna, Synthesis and in-vitro anti-HIV activities of Didanosine prodrugs, J. Enzyme Inhib. Med. Chem., 22, 51-55, 2007.
  65. A.S.K. Reddy,  J.V. Ragavendran, P. Yogeeswari, D. Sriram, Pharmacological screening of candidate anticonvulsants in the animal model of febrile seizures, Med. Chem. Res., 15, 285-286, 2007.
  66. K.N. Purna, P. Dhakla, P. Senthil Kumar, P. Yogeeswari, D. Sriram, 5-Nitro-2-furaldehyde thiosemicarbazones: Synthesis and in-vitro antimycobacterial activities, Med. Chem. Res., 15, 223-224, 2007.
  67. M. Dinakaran, C. Yogesh, P. Yogeeswari, D. Sriram, Synthesis of various 7-substituted-1-t-butyl-1,4-dihydro-8-methyl-6-nitro-4-oxo quiniline-3-carboxylic acid, Med. Chem. Res., 15, 328, 2007.
  68. J. V. Ragavendran, D. Sriram, S.K. Patel, I. Vikram Reddy, N. Bharathwajan, J. Stables, P. Yogeeswari, Design and Synthesis of Anticonvulsants from a Combined Phthalimide-GABA –Anilide and Hydrazone Pharmacophore, Eur. J. Med. Chem., 42, 146-151, 2007.
  69. P. Yogeeswari, J.V. Ragavendran, D. Sriram, Neuropathic pain: Strategies in drug discovery and treatment, Expert Opinion on Drug Discovery, 2, 169-184, 2007.
  70. D. Sriram, P. Yogeeswari, Prathiba Dakhla, P. Senthil Kumar, Debjani Banerjee, N-Hydroxythiosemicarbazones: Synthesis and in-vitro antitubercular activity, Bioorg. Med. Chem. Lett., 17, 1888-1893, 2007.
  71. D. Sriram, P. Senthilkumar, M. Dinakaran, P. Yogeeswari, A. China, V. Nagaraja, Antimycobacterial Activities of Novel 1-(Cyclopropyl/tert-butyl/4-fluorophenyl)-1,4-dihydro- 6-nitro-4-oxo-7-(substituted secondary amino)-1,8-naphthyridine-3-carboxylic Acid, J. Med. Chem. 50, 6232-6239, 2007.
  72. P. Yogeeswari, J. Vaigunda Ragavendran, D. Sriram, Y. Nageswari, R. Kavya, N. Sreevatsan, K. Vanitha, J. Stables, Discovery of 4-Aminobutyric acid derivatives possessing anticonvulsant and antinociceptive activities: A Hybrid pharmacophore approach, J. Med. Chem. 50, 2459-2467, 2007.
  73. D. Sriram, P. Yogeeswari, M. Dinakaran, R. Thirumurugan, Antimycobacterial activity of novel 1-(5-cyclobutyl-1,3-oxazol-2-yl)-3-(sub)phenyl/pyridylthiourea endowed with high activity toward multi-drug resistant tuberculosis, J. Antimicrob. Chemother., 59, 1194-1196, 2007.
  74. P. Yogeeswari, D. Sriram, P. Sahitya, J.V. Ragavendran, V. Ranganadh, Synthesis and anticonvulsant activity of 4-(2-(2,6-dimethylphenylamino)-2-oxoethylamino)-N-(substituted)butanamides: A Pharmacophoric hybrid approach, Bioorg. Med. Chem. Lett., 17, 3712-3715, 2007.
  75. D. Sriram, P. Yogeeswari, G. Senchani, D. Banerjee, Newer Tetracycline derivatives: Synthesis, anti-HIV, antimycobacterial activities and inhibition of HIV-1 integrase, Bioorg. Med. Chem. Lett., 17, 2372-2375, 2007.
  76. R.R. Kumar, S. Perumal, P. Senthilkumar, P. Yogeeswari, D. Sriram, An atom efficient, solvent-free, green synthesis and antimycobacterial evaluation of 2-amino-6-methyl-4-aryl-8-[(E)-arylmethylidene]-5,6,7,8-tetrahydro-4H-pyrano[3,2-c]pyridine-3-carbonitriles, Bioorg. Med. Chem. Lett., 17, 6459-6462, 2007.
  77. P. Yogeeswari,  J. Vaigunda Ragavendran, D. Sriram, R. Kavya, K. Vanitha, N. Harshini, Newer N-phthaloyl GABA derivatives with antiallodynic and antihyperalgesic activities in both sciatic nerve and spinal nerve ligation models of neuropathic pain, Pharmacology, 81, 21-31, 2008.
  78. R.R. Kumar, S. Perumal, P. Senthilkumar, P. Yogeeswari, D. Sriram. Discovery of antimycobacterial spiro-piperidin-4-ones: an atom economic, stereoselective synthesis, and biological intervention. J. Med. Chem. 51, 5731-5735, 2008.
  79. M. Dinakaran, P. Senthilkumar, P. Yogeeswari, A. China, V. Nagaraja, D. Sriram. Synthesis, antimycobacterial activities and phototoxic evaluation of 5H-thiazolo[3,2-a]quinoline-4-carboxylic acid derivatives. Med. Chem. 4, 482-491, 2008.
  80. M. Dinakaran, P. Senthilkumar, P. Yogeeswari, A. China, V. Nagaraja, D. Sriram. Novel ofloxacin derivatives: synthesis, antimycobacterial and toxicological evaluation. Bioorg. Med. Chem. Lett., 18, 1229-1236, 2008.
  81. D. Sriram, P. Yogeeswari, M. Dinakaran, M. Sowmya. Synthesis, anti-HIV and antitubercular activities of nelfinavir diester derivatives. Biomed. Pharmacother., 62, 1-5, 2008.
  82. P. Senthilkumar, M. Dinakaran, D. Banerjee, R.V. Devakaram, P. Yogeeswari, A. China, V. Nagaraja, D. Sriram. Synthesis and antimycobacterial evaluation of newer 1-cyclopropyl-1,4-dihydro-6-fluoro-7-(substituted secondary amino)-8-methoxy-5-(sub)-4-oxoquinoline-3-carboxylic acids. Bioorg. Med. Chem., 16, 2558-2569, 2008.
  83. M. Dinakaran, P. Senthilkumar, P. Yogeeswari, A. China, V. Nagaraja, D. Sriram. Antimycobacterial activities of novel 2-(sub)-3-fluoro/nitro-5,12-dihydro-5-oxobenzothiazolo[3,2-a]quinoline-6-carboxylic acid. Bioorg Med Chem., 16, 3408-3418, 2008.
  84. M. Dinakaran, P. Senthilkumar, P. Yogeeswari, A. China, V. Nagaraja, D. Sriram. Antimycobacterial and phototoxic evaluation of novel 6-fluoro/nitro-4-oxo-7-(sub)-4H-[1,3]thiazeto[3,2-a]quinoline-3-carboxylic acid. Int. J. Antimicrob. Agents., 31, 337-344, 2008.
  85. L. Sebastian, A. Desai, M.N. Shampur, P. Yogeeswari, D. Sriram, Vasanthapuram R. N-Methylisatin-beta-thiosemicarbazone derivative (SCH 16) is an inhibitor of Japanese encephalitis virus infection in vitro and in vivo. Virol. J., 5:64, 2008.
  86. J.V. Ragavendran, D. Sriram, S. Kotapati, J. Stables, P. Yogeeswari. Newer GABA derivatives for the treatment of epilepsy including febrile seizures: A bioisosteric approach. Eur. J. Med. Chem., In Press, 2008.
  87. M. Shalini, P. Yogeeswari, D. Sriram, J.P. Stables, Cyclization of the semicarbazone template of aryl semicarbazones: Synthesis and anticonvulsant activity of 4,5-diphenyl-2H-1,2,4-triazol-3(4H)-one, Biomed. Pharmacother., In Press, 2007.
  88. D. Sriram, Debjanai Banerjee, P. Yogeeswari, Efavirenz Mannich bases: Synthesis, anti-HIV and anitubercular activities, J. Enzyme Inhib. Med. Chem., In Press, 2007.
  89. P. Senthil Kumar, M. Dinakaran, P. Yogeeswari, A. China, V. Nagaraja, D. Sriram, Antimycobacterial activities of novel fluoroquinolones, Biomed. Pharmacother., In Press, 2007.
  90. M. Dinakaran, P. Senthil Kumar, P. Yogeeswari, D. Sriram, Antitubercular activities of novel benzothiazolo naphthyridone carboxylic acid derivatives endowed with high activity toward multi-drug resistant tuberculosis, Biomed. Pharmacother., In Press, 2007.
  91. D. Sriram, P. Yogeeswari, D.Y. Priya, Antimycobacterial activity of novel N-(substituted)-2-isonicotinoylhydrazino carbothioamade endowed with high activitytowards INH-resistant tuberculosis, Biomed. Pharmacother., In Press, 2008.

    Expert Reviewer for the following International Journals

  Invited Talks delivered:

1. Drug design based on Molecular Hybridization and Integration - "International Symposium on Recent Advances in Drug Design & Delivery systems"  26-27th Feb, 2005, BITS, Pilani, India.

2. Drug discovery strategies forthe treatment of Neuropathic pain - "National Conference on Recent Trends of Research in Pharmaceutical Sciences" 7-8th Jan, 2008, Nathdwara, India.

Papers presented in National/International Conferences (My Research group)

  1. P. Senthil Kumar, M. Dinakaran, P. Yogeeswari, D. Sriram, A. China, V. Nagaraja, Synthesis and antimycobacterial activities of novel 6-nitoquinolones-3-carboxylic acid, 59 th Indian Pharmaceutical Congress,20-23rd December 2007, Varanasi, India.

  2. A. Sunil Kumar Reddy,  D. Sriram, V. Ranganadh, P. Yogeeswari, Synthesis  of newer N-spiro substituted GABA derivatives as anticonvulsants, 59th Indian Pharmaceutical Congress,20-23rd December 2007, Varanasi, India.

  3. Meena K. Purohit, Niloufer M, P. Senthil Kumar, P. Yogeeswari, D. Sriram, A facile microwave-assisted synthesis of novel 3,5-dinitrosalicylamides and their antimycobacterial activity, 59th Indian Pharmaceutical Congress,20-23rd December 2007, Varanasi, India.

  4. Niloufer M, Meena K. Purohit, P. Senthil Kumar, J. Vaigunda Ragavendran, M. Arjun, D. Sriram, P. Yogeeswari,  Synthesis, antiallodynic and antihyperalgesic activities of 5-(4-nitrophenyl)furoic 2-acid hydrazones in two in-vivo models of neuropathic pain, 59th Indian Pharmaceutical Congress,20-23rd December 2007, Varanasi, India.

  5. D. Sriram, M. Dinakaran, R.V. Devakaram, P. Yogeeswari, Synthesis and antimalarial activity of aromatic amino analogues of artemisinin, 58th Indian Pharmaceutical Congress, 1-3rd December 2006, Mumbai, India.

  6. A.S.K. Reddy, Y. Nageswari, S.K. Patel, D. Sriram, P. Yogeeswari, Newer GABA analogs as CNS agents: Synthetic integration of GABA in 1,2,4-triazol-2H-3-one, 58th Indian Pharmaceutical Congress, 1-3rd December 2006, Mumbai, India.

  7. P. Senthil kumar, M. Dinakaran, P. Yogeeswari, D. Sriram, Synthesis and in vitro antimycobacterial activity of some novel fluoroquinolones, 58th Indian Pharmaceutical Congress, 1-3rd December 2006, Mumbai, India.

  8. J.V. Ragavendran, I. Vikram Reddy, P. Yogeeswari, D. Sriram, Synthesis of 4-{[(3Z)-2-oxo-1,2-dihydro-3H-indol-3-ylidene]amino}-N-substituted phenyl) butanamides possessing antiallodynic and antihyperalgersic activities in two rat models of neuropathic pain, 3rd International Symposium on Current Trends In Drug Discovery Research CTDDR - 2007, 17 - 21st February 2007, Chandigarh, India.

  9. D. Banerjee, T.R. Bal, P. Yogeeswari, D. Sriram, L. Sebastin, A. Desai, S.N. Madhusudhana, V. Ravi, Isatin derivatives inhibit Japanese encephalitis virus entry and replication in-vitro, 3rd International Symposium on Current Trends In Drug Discovery Research CTDDR - 2007, 17 - 21st February 2007, Chandigarh, India.

  10. P. Senthil Kumar, M. Dinakaran, P. Yogeeswari, D. Sriram, Synthesis and antitubercular activities of 1-(cyclopropyl/t-butyl/4-fluorophenyl)-1,4-dihydro-6-nitro-4-oxo-7-(substituted secondary amines)-1,8-naphthyridine-3-carboxylic acid, 3rd International Symposium on Current Trends In Drug Discovery Research CTDDR - 2007, 17 - 21st February 2007, Chandigarh, India.

  11. A.S.K. Reddy,  J.V. Ragavendran, P. Yogeeswari, D. Sriram, Pharmacological screening of candidate anticonvulsants in the animal model of febrile seizures, 3rd International Symposium on Current Trends In Drug Discovery Research CTDDR - 2007, 17 - 21st February 2007, Chandigarh, India.

  12. K.N. Purna, P. Dhakla, P. Senthil Kumar, P. Yogeeswari, D. Sriram, 5-Nitro-2-furaldehyde thiosemicarbazones: Synthesis and in-vitro antimycobacterial activities, 3rd International Symposium on Current Trends In Drug Discovery Research CTDDR - 2007, 17 - 21st February 2007, Chandigarh, India.

  13. M. Dinakaran, C. Yogesh, P. Yogeeswari, D. Sriram, Synthesis of various 7-substituted-1-t-butyl-1,4-dihydro-8-methyl-6-nitro-4-oxo quiniline-3-carboxylic acid, 3rd International Symposium on Current Trends In Drug Discovery Research CTDDR - 2007, 17 - 21st February 2007, Chandigarh, India.

  14. P. Yogeeswari, Synthesis of 4-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)N-(substitutedphenyl)butanamides possessing antiallodynic and antihyperalgesic activities in two rat models of neuropathic pain, 11th APTI National Convention, 1-3 September, 2006. (WON THE BEST PAPER IN PODIUM SECTION)

  15. P. Yogeeswari, R. Kavya, V. Reddy, D. Sriram, Newer approaches in the design of Anticonvulsants effective in hyperthermia-induced febrile seizures, 6th Asian & Oceanian Epilepsy Congress, 16-19th Novemeber 2006, Kuala Lumpur, Malaysia.

  16. D. Sriram, S. Mehta, Discovery of lesser neurotoxic and effective anticonvulsant agents active in four animal models of seizure, 6th Asian & Oceanian Epilepsy Congress, 16-19th Novemeber 2006, Kuala Lumpur, Malaysia.

  17. V. Ragavendran, R. Kumar, P. Yogeeswari, Design of GABA uptake inhibitors: Synthesis and anticonvulsant properties, 6th Asian & Oceanian Epilepsy Congress, 16-19th Novemeber 2006, Kuala Lumpur, Malaysia.

  18. D. Sriram, M. Dinakaran, R.V. Devakaram, P. Yogeeswari, Synthesis and antimalarial activity of aromatic amino analogues of artemisinin, 58th Indian Pharmaceutical Congress, 1-3rd December 2006, Mumbai, India.

  19. A.S.K. Reddy, Y. Nageswari, S.K. Patel, D. Sriram, P. Yogeeswari, Newer GABA analogs as CNS agents: Synthetic integration of GABA in 1,2,4-triazol-2H-3-one, 58th Indian Pharmaceutical Congress, 1-3rd December 2006, Mumbai, India.

  20. P. Senthil kumar, M. Dinakaran, P. Yogeeswari, D. Sriram, Synthesis and in vitro antimycobacterial activity of some novel fluoroquinolones, 58th Indian Pharmaceutical Congress, 1-3rd December 2006, Mumbai, India.

  21. Rohit Nelli, P. Senthil Kumar, P. Yogeeswari, D. Sriram, Microwave-assisted synthesis of some novel 2-[3-(4-bromo-2-fluorobenzyl)-4-oxo-3,4-dihydrophthalazin-1-yl]-N-substituted amides, National Symposium on Challenges in Drug Discovery Research: Networking Opportunities between Academia & Industries, 7-8th April, 2006, Pilani, India.

  22. V. Ranganadh, P. Roheeth Kumar, M. Mallika, P. Yogeeswari, D. Sriram, Synthesis of copper complexes of thiosemicarbazones as antitumour agents, National Symposium on Challenges in Drug Discovery Research: Networking Opportunities between Academia & Industries, 7-8th April, 2006, Pilani, India.

  23. J.V. Ragavendran, R. Kavya, S.K. Patel, D. Sriram, P. Yogeeswari, Design and synthesis of 4-[(2-oxo-1,2-dihydro-3H-indol-3-ylidene)amino] butanmaides as 4-aminobutyric acid (GABA) mimetics,  National Symposium on Challenges in Drug Discovery Research: Networking Opportunities between Academia & Industries, 7-8th April, 2006, Pilani, India.

  24. Y. Nageswari, P. Sahithya, J.V. Ragavendran, D. Sriram, P. Yogeeswari, Synthesis and anticonvulsant evaluation of 2,6-dimethylphenylaminoacetylamino butanamides, National Symposium on Challenges in Drug Discovery Research: Networking Opportunities between Academia & Industries, 7-8th April, 2006, Pilani, India.

  25. M. Mallika, P. Yogeeswari, D. Sriram, Design and synthesis of gold (III) and platinum (III) complexes of aryl-substituted semicarbazones as antitumour agents, National Symposium on Challenges in Drug Discovery Research: Networking Opportunities between Academia & Industries, 7-8th April, 2006, Pilani, India.

  26. Jatinder Kaur, Simarjeet Kaur, P. Yogeeswari, D. Sriram, Pharmacophore modeling of COX-2 inhibitors, National Symposium on Challenges in Drug Discovery Research: Networking Opportunities between Academia & Industries, 7-8th April, 2006, Pilani, India.

  27. Debjani Banerjee, M. Dinakaran, P. Senthil Kumar, R.V. Devakaram, P. Yogeeswari, D. Sriram, Synthesis and Antibacterial evaluation of Phenothiazine derivatives, National Symposium on Challenges in Drug Discovery Research: Networking Opportunities between Academia & Industries, 7-8th April, 2006, Pilani, India.

  28. Bhargava, P. Senthil Kumar, P. Yogeeswari, D. Sriram, Synthesis of certain 7-substituted fluoroquinolones, National Symposium on Challenges in Drug Discovery Research: Networking Opportunities between Academia & Industries, 7-8th April, 2006, Pilani, India.

  29. Y. Nageswari, J.V. Ragavendran, D. Sriram, P. Yogeeswari, Design and Synthesis of 4-(1,3-Dioxoisoindolin-2-yl)butane hydrazones as anticonvulsant pharmacophoric hybrids, 2nd International Symposium on Drug Discovery & Process Research, 10-12th Feb, 2006, Belgaum, India.

  30. J.V. Ragavendran, S.K. Patel, D. Sriram, P. Yogeeswari, Design and Synthesis of Newer amino derivatives of 4-aminobutyric acid as anticonvulsants, 2nd International Symposium on Drug Discovery & Process Research, 10-12th Feb, 2006, Belgaum, India.

  31. R. Kavya, J.V. Ragavendran, D. Sriram, P. Yogeeswari, Pharmacological evaluation of the analgesic efficacy of candidate anticonvulsant compounds in neuropathic pain models, 2nd International Symposium on Drug Discovery & Process Research, 10-12th Feb, 2006, Belgaum, India.

  32. M. Shalini, J.V. Ragavendran, P.R. Kumar, D. Sriram, P. Yogeeswari, Quantum mechanical modeling of aryl semicarbazones as anticonvulsants, 2nd International Symposium on Drug Discovery & Process Research, 10-12th Feb, 2006, Belgaum, India.

  33. P. Yogeeswari, J.V. Ragavendran, Animal models of seizures, '6th EMBL International Predoc Symposium "Animal Models - Tips and Tricks from Nature", 11-13th May 2005, Rome, Italy.

  34. P. Yogeeswari, Drug design based on Molecular hybridization and integration, International Symposium on Recent Advances in drug design and delivery systems, 26-27th Feb, 2005, BITS, Pilani, India.

  35. D. Sriram, T.R. Bal, P. Yogeeswari, Aminopyrimidinimino isatin analogues: Design and synthesis of novel non-nucleoside HIV-1 reverse transcriptase inhibitors with broad spectrum Antimicrobial properties, National Symposium on Futiritic trends in Pharmacotherapeutics and formulation development, Banaras Hindu University, Varanasi, March 4-5th, 2005.

  36. P. Yogeeswari, D. Sriram, P. Roheeth Kumar, Development of Anticonvulsant leads by integrating structure-based drug design and database screening, National Symposium on Futiritic trends in Pharmacotherapeutics and formulation development, Banaras Hindu University, Varanasi, March 4-5th, 2005.

  37. R.V. Devakaram, N.S. Myneedu, P. Yogeeswari, D. Sriram, Microwave-assisted synthesis and anti-YFV activity of 2,3-diaryl-1,3-thiazolidin-4-ones, International Symposium on Recent Advances in drug design and delivery systems, 26-27th Feb, 2005, BITS, Pilani, India.

  38. P.R. kumar, G.A. Nilkanth, P. Yogeeswari, Rational approach for the design of a central nervous system active chemical library, International Symposium on Recent Advances in drug design and delivery systems, 26-27th Feb 2005, BITS, Pilani, India.

  39. K. Srikanth, V. Ranganadh, D.R.K. Vyas, B. Murali Krishna, P. Yogeeswari, D. Sriram, Design of anticonvulsant drug database, International Symposium on Recent Advances in drug design and delivery systems, 26-27th Feb, 2005, BITS, Pilani, India.

  40. V.N.R. Pavan Kumar, P. Yogeeswari, D. Sriram, T.R. Bal, QSAR studies on Non-Nucleoside reverse transcriptase inhibitors belonging to phenylethylthiazolylthiourea, International Symposium on Recent Advances in drug design and delivery systems, 26-27th Feb, 2005, BITS, Pilani, India.

  41. P. Kudyar, P. Yogeeswari, M. Shalini, D. Sriram, Synthesis of 2,5-dimethylphenyl substituted semicarbazones as anticonvulsants, International Symposium on Recent Advances in drug design and delivery systems, 26-27th Feb, 2005, BITS, Pilani, India.

  42. K. Purna Nagasree, P. Yogeeswari, D. Sriram, Newer isonicotinoyl hydrazones: Synthesis and in-vitro antimycobacterial activity, International Symposium on Recent Advances in drug design and delivery systems, 26-27th Feb, 2005, BITS, Pilani, India.

  43. J. V. Ragavendran, P. Yogeeswari, R. Thirumurugan, D. Sriram, In-vitro and ex-vivo enzyme inhibition studies on some BITS anticonvulsant compounds, International Symposium on Recent Advances in drug design and delivery systems, 26-27th Feb, 2005, BITS, Pilani, India.

  44. M. Shalini, P. Yogeeswari, D. Sriram, J. P. Stables, Synthesis of some 4,5-(substituted diphenyl)-2H-1,2,4-triazole-3(4H)-one derivatives and their anticonvulsant properties, International Symposium on Recent Advances in drug design and delivery systems, 26-27th Feb, 2005, BITS, Pilani, India.

  45. R. Kavya, S. Tiwari, P. Yogeeswari, D. Sriram, Synthesis and in-vitro cytotoxicity evaluation of gatifloxacin Mannich bases, International Symposium on Recent Advances in drug design and delivery systems, 26-27th Feb, 2005, BITS, Pilani, India.

  46. T.R. Bal, P. Yogeeswari, D. Sriram, Aminopyrimidinimino isatin analogues: Design and synthesis of novel non-nucleoside HIV-1 reverse transcriptase inhibitors with broad spectrum Antimicrobial properties, International Symposium on Recent Advances in drug design and delivery systems, 26-27th Feb, 2005, BITS, Pilani, India.

  47. R. Kavya, R. Thirumurugan, D. Sriram, P. Yogeeswari; “Pharmacological Evaluation of aryl(heteroaryl) semi(thio)carbazones for CNS activity” 55th Indian Pharmaceutical congress, Chennai, December 19-21, 2003.

  48. J. Vaigunda Ragavendran, R. Thirumurugan, I. Sridharan, D. Sriram, P. Yogeeswari; “4-amino butyrate amino transferase (GABA-T) inhibition as a possible mechanism of some novel anticonvulsant aryl semicarbazones”, 55th Indian Pharmaceutical Congress, Chennai, December, 19-21, 2003.

  49.  R. Thirumurugan, D. Sriram, P. Yogeeswari; “Design and synthesis of novel aryl semicarbazone derivatives as anticonvulsants with GABA and glycine mediated mechanism”, International symposium on drug discovery and process research, Shivaji University, Kolhapur – 416004, January 23-25, 2003.

  50. T. R. Bal, D. Sriram, P. Yogeeswari, Non-nucleoside reverse transcriptase inhibitors for the treatment of AIDS, International symposium on Emerging trends in Genomics and Proteomics education and research, BITS, Pilani, Jan 12-13th, 2003.

  51. K. Jyothi Mallika, R. Thirumurugan, N.S. Chakravarthy, P. Yogeeswari, D. Sriram; “Tetrahydro-2H-1,3,5-thiadiazine-5-(4-Pyridyl carboxamide)-2-thione derivatives as prodrugs for isoniazid : synthesis and Antituberculous Activity”, 54th Indian Pharmaceutical Congress, Pune, December, 13-15, 2002.

  52. I. Sridharan, B. Archana, R. Thirumurugan, P. Yogeeswari, D. Sriram; “γ-Aminobutyric acid (GABA) level studies on novel anticonvulsant compounds in rat brain tissue preparation”, 54th Indian Pharmaceutical Congress, Pune, December 13-15, 2002.

    

                        Academic Activities:

 

    BOOK

Textbook on  Medicinal Chemistry -

 Released by Pearson Education Singapore Ltd. released in Jan 2007.

www.pearsoned.co.in/dsriram

 

Courses Handled / Handling

 

Higher Degree Courses

 

Advanced Medicinal Chemistry

Computer-Aided Drug Design

Advanced Pharmacology

Chemistry of Macromolecules

 

            First Degree Courses

 

Natural Drugs

Chemistry of Organic Compounds

Medicinal Chemistry

Phytochemistry

Pharmaceutical Analysis

Measurement Techniques-I (Chemistry)

 

Family Details

My Husband Dr. D.Sriram &

Our Sons RAGHAV, Y.S and VAISHNAV, Y.S.

 

 

 

 

 

YOUNG PHARMACY TEACHER OF THE YEAR 2007 AWARD Presented by Association of Pharmacy Teachers of India

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Last updated 27th November, 2008

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